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肿瘤治疗用重组内皮抑素CHO细胞的微囊化研究

, 2007
微囊化基因工程细胞移植是一种新兴的肿瘤抗血管治疗方法，如果将此技术应用到临床研究，就需要制备大量的细胞活性良好、重组蛋白表达量高的生物微胶囊，然而由于目前生物微胶囊规模化制备和培养技术还不成熟，阻碍了其在临床治疗中的推广与应用。本论文以重组CHO细胞为模型，探索了微囊化重组细胞制剂规模化制备方法及其在肿瘤治疗中应用的可行性。 微囊化重组CHO细胞体外和体内都能迅速生长和表达内皮抑素，并且体外可以抑制牛主动脉血管内皮细胞增殖，体内可以抑制鸡胚尿囊膜血管生成。 确定了移植用微囊化重组细胞制剂的最佳条件 ...
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[Radiotherapy for SMARCA4-deficient Pulmonary Neoplasms: 
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Zhongguo Fei Ai Za Zhi
Gu Y, Gao R, Fan X, Ge X.
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[Clinical strategies and indication expansion of interventional ultrasonography ablative therapy for hepatic tumors]. [PDF]

Zhonghua Gan Zang Bing Za Zhi
Liang YG, Wang HY, Zhao QY, Jiang TA.
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[Current status and prospects of family financial toxicity in childhood malignancies]. [PDF]

Zhongguo Dang Dai Er Ke Za Zhi
Wu ST, Wang CL, Shi DR.
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Ferroptosis and tumor immunity. [PDF]

Zhong Nan Da Xue Xue Bao Yi Xue Ban
Tao Q, Liu N, Chen J, Wu J, Li J, Chen X, Peng C.   +6 more
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[The application of surgical robots in head and neck tumors]. [PDF]

Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi
Huang X, He Q, Wang D, Yan J, Wang Y, Liu X, Zheng C, Xu Y, Bai Y, Li C, Sun R, Wang X, Xiang M, Wang Y, Lu X, Tao L, Song M, Liang Q, Zhang X, Hu Y, Chen R, Liu Z, Liang F, Han P.   +23 more
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[Research Progress on the Role and Mechanisms of PYCR1 
in Tumorigenesis and Progression]. [PDF]

Zhongguo Fei Ai Za Zhi
Meng Y, Yang Z, Feng H, Li H, Li B.
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[Combined Analysis of Dyslipidemia and Tumor Markers for the Diagnosis of Gastric Cancer]. [PDF]

Sichuan Da Xue Xue Bao Yi Xue Ban
Lu J, Xu R, Li T, Zheng B, Li M.
europepmc   +1 more source

[Multi-modal tumor boundary clustering recognition based on artificial intelligence virtual cells and near-infrared surgical field]. [PDF]

Sheng Wu Yi Xue Gong Cheng Xue Za Zhi
Li W, Wang T, Yang X, Zhou F.
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[Bifunctional biomaterials: An innovative strategy for synergistic bone tumor therapy and bone regeneration]. [PDF]

Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi
Feng W, Chang B, Wang C, Fan B.
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