Results 31 to 40 of about 26,866 (168)

Status quo and influencing factors of cancer-related cognitive impairment in patients with bone metastasis (骨转移瘤患者癌症相关认知功能障碍现状及影响因素分析)

open access: yes中西医结合护理
Objective To explore the status quo and influencing factors of cancer-related cognitive impairment (CRCI)in patients with bone metastasis. Methods From December 2023 to December 2024, 139 patients with bone metastasis in Chongqing cancer hospital were ...
ZHAO Lingling (赵玲玲)   +3 more
doaj   +1 more source

Nursing of a patient with gastroparesis syndrome after gastrectomy for gastric cancer treated with Traditional Chinese Medicine ointment massage and acupoint application (中药膏摩联合穴位贴敷治疗1例胃癌术后并发胃瘫综合征患者的护理体会)

open access: yes中西医结合护理, 2022
This paper summarized the nursing management for a patient with gastroparesis syndrome after gastrectomy for gastric cancer treated with Traditional Chinese Medicine (TCM) ointment massage and acupoint application.
ZHAO Baoya (赵保亚)   +3 more
doaj   +1 more source

Functions of Periostin in pre-metastatic immunosuppressive niches of breast tumor metastasis [PDF]

open access: yes, 2016
在肿瘤发生发展过程中,肿瘤细胞及其相关间质细胞向肿瘤微环境中分泌大量促癌细胞因子以及趋化因子,促使骨髓来源的免疫抑制细胞(myeloid-derivedsuppressorcells,MDSCs)向远处靶器官浸润,形成免疫抑制微环境,为肿瘤细胞的转移提供有利条件,从而促进肿瘤细胞的转移。在乳腺癌肿瘤组织中,细胞外基质蛋白Periostin主要由肿瘤相关成纤维细胞分泌,并参与调控肿瘤的发生发展过程。然而,关于Periostin蛋白在MDSCs介导的转移前微环境形成中的功能尚不清楚 ...
熊珊珊
core  

Quantum Dots for Biomedical Biosensing, NIR‐II Bioimaging, and Phototherapy: Materials Design, Signal Transduction, and Translational Barriers

open access: yesAdvanced Science, EarlyView.
This review outlines bottom‐up and biomimetic fabrication strategies of quantum dots, and highlights their emerging applications in biosensing, multimodal bioimaging, and intelligent cancer theranostics. It further discusses key translational barriers and future perspectives for advancing QD‐based nanomedicine toward clinical implementation.
Jie Ju   +5 more
wiley   +1 more source

Analysis of current status and influencing factors on quality of life in patients with spinal metastases (脊柱转移瘤患者生存质量现状及影响因素分析)

open access: yes中西医结合护理
Objective To explore the status quo and influencing factors of quality of life in patients with spinal metastases. Methods From January 2024 to November 2024, 143 patients with spinal metastasis in Chongqing cancer hospital were selected by the ...
XIE Chunhua (谢春花)   +2 more
doaj   +1 more source

Preparation and Characterization of Anti-Neuropilin2 Monoclonal Antibody and Its Preliminary Application [PDF]

open access: yes, 2016
研究背景和目的 Neuropilin2(NRP2)是一种多功能的新型受体,在神经系统发育、心血管系统、免疫系统及淋巴管生成等过程中发挥重要作用。最新研究表明,NRP2受体广泛表达于肿瘤细胞表面,与肿瘤血管形成以及肿瘤的发生发展、凋亡、粘附、侵袭和转移等生物学行为密切相关。多种肿瘤细胞均高表达NRP2,提示NRP2可能成为一种新型肿瘤标志物。NRP2通过多种机制调控肿瘤进展,NRP2-b1b2是其发挥作用的重要结构域,NRP2-b1b2结构域可以结合配体Ⅲ型Semaphorin和VEGF ...
杨芸
core  

Breaking through tradition: A new study on the 125I seeds implantation assisted by the puncture angle guidance device

open access: yesPrecision Medical Sciences, EarlyView.
This study showed the puncture angle guide device assisted 125I seeds implantation is safe and feasible. Compared with the manual deployment of needles, the puncture time, the number of puncture needle adjustments, and the number of intraoperative CT scans are significantly reduced, which can be used in clinical applications.
Yufeng Zhang   +7 more
wiley   +1 more source

Research on the effect of DHA on glucose metabolism in human lung cancer cells and its anti-tumor mechanism [PDF]

open access: yes, 2015
研究背景及目的: 肺癌是人类最常见的恶性肿瘤之一,尽管近年来治疗取得了很大进展,治疗效果仍然较差。癌细胞具有偏向通过糖酵解方式来进行糖代谢获得能量的代谢特征使得肿瘤细胞能够比正常细胞具有更强的葡萄糖代谢能力,为肿瘤细胞的快速增殖与生长提供了能量来源,也使其具备更强的凋亡抵抗能力。天然产物凭借其来源广泛、类型多样、不良反应小,具有开发为化疗药物增效减毒辅助药物的潜力等特点备受关注。双氢青蒿素是青蒿叶中分离的有效抗疟成分,体内代谢活性产物为双氢青蒿素。药物学研究证实青蒿素类药物具有抗疟、抗血吸虫 ...
米彦军
core  

Age‐Associated Targetable Genomic Alterations and PD‐L1 Expression in 2509 Patients With Pulmonary Ground‐Glass Opacities

open access: yesCancer Medicine, Volume 15, Issue 5, May 2026.
ABSTRACT Aim To investigate the landscape of targetable genomic alterations and programmed cell death ligand 1 (PD‐L1) expression in pulmonary ground‐glass opacities (GGOs) and their association with age. Methods A total of 2509 patients with GGOs were retrospectively analyzed.
Wen‐Fang Tang   +16 more
wiley   +1 more source

基于直线加速器的海马体保护性全脑放疗的剂量学优化

open access: yesFushe yanjiu yu fushe gongyi xuebao
本研究使用双弧容积旋转调强放射治疗(VMAT)技术,探寻海马体剂量最低的多叶准直器角度并分析其原因,为临床治疗计划提供参考。随机选择10例脑转移瘤行全脑放疗的患者,为每位患者制作多个不同对称多叶准直器角度组合的海马体保护性全脑放疗(HA-WBRT)计划。在满足计划靶区(PTV)和危及器官的剂量学要求的前提下限制海马体的剂量。分析这些计划靶区的适形性指数、均匀性指数、D2%、D98%、机器跳数、治疗时间等靶区参数和海马体、晶状体、眼球、视神经和视交叉等危及器官的剂量,来评估不同多叶准直器计划的优劣 ...
王 宇, 许 德颖, 刘 云峰, 于 亮
doaj   +1 more source

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