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六维床在头、胸、腹部肿瘤常规直线加速器放射治疗中的摆位误差回顾性分析
Fushe yanjiu yu fushe gongyi xuebao回顾性分析基于加速器六维床摆位的肿瘤患者的CBCT（Cone-Beam CT，CBCT）图像，比较患者的摆位误差数据，分析肿瘤患者六维床放射治疗中分次内摆位误差的数据，研究六维床对不同位置肿瘤产生的摆位效果差异。选取2020年3月至2023年9月于本中心接受放疗的肿瘤患者85例，分成脑瘤、肺癌、直肠癌和乳腺癌。统计4组患者在左右、头脚、腹背6个自由度（X、Y、Z和Rx、Ry、Rz）的首次和分次内摆位误差。采用双样本异方差t检验对比分析不同瘤种在各个方向上的分次内摆位误差 ...
万 宝 +8 more
doaj +1 more source
The effects of axon guidance factor Slit3 on metastasis of human fibrosarcoma [PDF]
, 2015 我们通过在纤维肉瘤细胞HT1080过表达Slit3基因，分析Slit3对肿瘤细胞侵袭转移作用.Transwell侵袭实验中，Slit3过表达后抑制HT1080的迁移侵袭，在裸鼠皮下成瘤实验中，肿瘤体积明显变小、重量明显降低，Slit3过表达后抑制HT1080肿瘤细胞的侵袭转移。此外肿瘤切片HE染色后发现GFP组有病灶点，而slit3过表达则少见，这个结果说明，Slit3显著抑制HT1080细胞转移。slit3过表达后MMP2,MMP9的表达明显降低，而MMP3，MMP13表达量上调 ...
刘咏梅
core
Annual Review of Systemic Medical Treatment for Colorectal Cancer in 2025
Cancer Innovation, Volume 5, Issue 2, April 2026.Tissue biopsy and molecular profilingenable precise patient stratification into distinct molecular subtypes, which guides the selection of precision treatment. Furthermore, longitudinal liquid biopsies facilitate serial ctDNA monitoring for MRD detection and continuous surveillance.
Zengzhi Cai +3 more
wiley +1 more source
中西医结合护理Objective To evaluate the effect of auricular thumbtack needle embedding combined with Traditional Chinese Medicine(TCM) five-element music therapy on anxiety, depression, and sleep quality in patients with malignant lymphoma during the chemotherapy ...
HUANG Silin (黄思霖) +4 more
doaj +1 more source
Design, Synthesis and Evaluation of Novel Benzamide Derivatives as Antitumor Agents [PDF]
, 2016 肿瘤作为威胁人类身体健康的一种重大疾病，其治疗一直被全世界所重视。随着研究的不断深入，研究发现肿瘤是复杂的疾病，其生长和存活不仅仅依赖于一种受体或一种信号通路。单一靶点药物不能阻断肿瘤的所有信号通路，而联合用药又有可能影响药物的吸收和代谢，甚至造成更加严重的药物不良反应。因此，多靶点抗肿瘤药物随之诞生，它能够同时作用于某一肿瘤的多个靶点从而产生多种药理活性。相较于单一靶点而言，具有避免药物相互影响、作用全面、不良反应少等优势。 本文以课题组前期研究中发现的化合物HJ-47和YSM-14为先导化合物 ...
黄志宁
core
Policies and reporting guidelines for small biopsy specimens of mediastinal masses [PDF]
, 2014 目前，胸腺恶性肿瘤治疗方案大多是根据术\ud 后病理确定，然而，多数临床治疗决策需要在术前\ud 通过活检小标本的病理报告来制定。所以，术前活\ud 检小标本的正确获取和病理解读对治疗决策的制定\ud 显得非常重要[1]。这些标本包括细针活检标本，带\ud 芯穿刺活检标本和手术切取活检标本[2-7]。由于胸\ud 腺肿瘤的病理诊断对组织的获取方法和获取量都有较高\ud 的要求，加之对病理的描述也没有统一的标准，使得小\ud 标本在诊断胸腺瘤方面存在诸多问题。为此，ITMIG在\ud ...
Marchevsky, A +7 more
core +3 more sources
Cancer Medicine, Volume 15, Issue 4, April 2026.ABSTRACT Disorders of lipid metabolism contribute to the occurrence and progression of hematological malignancies, including chronic lymp hocytic leukemia (CLL). The objective of this study was to investigate the association between serum lipid levels and prognosis in patients with CLL.
Weiran Lv +9 more
wiley +1 more source
中西医结合护理To summarize the experience of hospice care with Traditional Chinese Medicine characteristics in the end-stage of a patient with small cell lung cancer with multiple systemic metastases.
LU Meiling (卢美玲)
doaj +1 more source
MedComm, Volume 7, Issue 4, April 2026.ABSTRACT The value of microbial metabolites in prognosis and treatment response prediction in patients with nasopharyngeal carcinoma (NPC) remains unclear. Here, through the untargeted metabolomic analysis of plasma in 48 paired NPC patients with or without tumor relapse, we identified distinct circulating metabolite atlases between NPC patients with ...
Jun‐Yan Li +16 more
wiley +1 more source
EFNA4 Effecting On EphA2 Regulates Cell Adhesion And Metastasis In Breast Cancer [PDF]
, 2016 实验背景：肿瘤细胞对临近组织和器官的侵袭与远端转移，一直是肿瘤研究的热点。酪氨酸受体蛋白及其配体家族Ephs和Ephrins之间的作用被证实能够调控多种肿瘤细胞的形态，细胞骨架，进而影响细胞的迁移与转移。前期通过荧光定量RT-PCR，我们发现相对于正常组织来源的细胞系，EFNA4在乳腺癌和肝癌细胞系中表达较低。同时在建立的高低侵袭ZR-75-30乳腺癌细胞系中，EFNA4具有表达差异，而EFNA4在肿瘤中的作用鲜有报道。 实验方法与结果：在体外实验中 ...
王恒
core