Results 71 to 80 of about 26,866 (168)
A study about the impact of overpression of Oct4 and Sox2 gene on gastric cancer cell biology and oncology characteristics [PDF]
目的:通过构建过表达干细胞因子Oct4和Sox2的胃癌SGC7901细胞株,研究过表达干细胞因子Oct4和Sox2对SGC7901胃癌细胞干细胞特性、肿瘤学特性、及生物学特性的影响,并探讨Oct4及Sox2在肿瘤细胞中的作用机制。 方法:1.构建携带Sox2基因的重组质粒,慢病毒载体感染SGC7901-OCT4细胞株得到SGC7901-OCT4-SOX2稳转细胞株。2.利用荧光定量PCR、western–bloting检测过表达Oct4及Sox2的胃癌SGC7901细胞中胃癌干细胞标志基因表达情况。3 ...
李文鹏
core
Ovarian Cancer and High Body‐Mass Index: A Global Burden of Disease Database Study From 1990 to 2021
ABSTRACT Background Excess adiposity has been recognized as a significant modifiable risk factor for ovarian cancer (OC), but the epidemiology of OC attributable to high BMI remain largely unknown. Methods Utilizing comprehensive data from the Global Burden of Disease 2021 study, this investigation quantifies the epidemiological impact of elevated body
Xiaolong Li +4 more
wiley +1 more source
ABSTRACT Background Neoadjuvant therapies, including chemotherapy (NACT), chemoradiotherapy (NACRT), and chemoimmunotherapy (NACIT), are standard for locally advanced gastric cancer (LAGC). Pathological response is a key surrogate for treatment effectiveness, but its correlation with long‐term outcomes across modalities remains unclear.
Yongfeng Zhu +9 more
wiley +1 more source
Research progress of Ruyi Jinhuang Powder in the treatment of pressure injuries (如意金黄散治疗压力性损伤的研究进展)
Pressure injury (PI) is a common skin problem that occurs most often in patients who are bedridden or have limited mobility, seriously affecting the quality of life of patients.
ZHU Yuxin (朱雨昕) +2 more
doaj +1 more source
The Expression and Biological Significance of PD-L1 on Lung Cancer Cell Lines [PDF]
Background and objective Tumor-associated PD-L1 expression was recently shown to promote T-cell apoptosis and proposed as a potential mechanism of immune evasion by tumors. On the basis of the ability of tumor-associated PD-L1 to mediate activated T-cell
Cheng CHEN +6 more
core
<正>从世界范围看,头颈部恶性肿瘤的发病率较高,口腔恶性肿瘤属于头颈部肿瘤,位居全身恶性肿瘤的第六位。在我国,口腔颌面部的恶性肿瘤以鳞状细胞癌最为多见,占80%以上。口腔癌(OSCC)转移是导致患者死亡的主要原因,在肿瘤转移的过程中,肿瘤细胞诱导血管的形成、肿瘤细胞黏附能力的变化、破坏细胞外基质(ECM),肿瘤细胞的运动能力和逃避免疫监视对肿瘤的转移也起了重要作用。
高瑞琪, 姜智雯, 秦高伟, 刘新
doaj
Sugar-targeted theranostics for research on localization of tumors [PDF]
随着癌症发病率和死亡率的日益提高,发展一种辅助癌症治疗的技术具有重要的临床意义。手术切除是治疗癌症的首选方式之一。医生在进行手术切除时常因为无法精确定位肿瘤而造成肿瘤的多切或少切,继而导致肿瘤的复发。为此,人们积极探索光学探针来辅助医生分辨肿瘤。为了获得高的信噪比,光学探针需要与一些靶向基团连接,常用的靶向基团有抗体、叶酸、多肽及核酸适配体等。而糖分子作为一种靶向基团用于术中肿瘤的成像却不曾有研究。肝细胞癌往往形成4-8cm时才能出现一定的特征,所以人们无法发现微小尺寸的肝癌病灶。目前临床上 ...
吴选俊
core
Effects of Rh-endostar in Combination with Radiotherapy on Rats with Lung Cancer [PDF]
Background and objective Radiation sensitivity is closely related to tissue oxygen, and rh-endostatin can induce the high level of oxygen content in tumor by "normalizing" tumor angiogenesis which is associated with radiotherapy sensitivity.
Changhu LI +5 more
core
With the transformation of medical model, patients have higher requirements for clinical nursing services. Humanistic care is the core content of modern nursing, which can enhance the nurse-patient relationship and improve the patient treatment ...
TANG Qian (唐倩) +4 more
doaj +1 more source
TACE with Ar-He Cryosurgery Combined Minimal Invasive Technique for the Treatment of Primary NSCLC in 139 Cases [PDF]
Background and objective TACE, Ar-He target cryosurgery and radioactive seeds implantation are the mainly micro-invasive methods in the treatment of lung cancer.
Dongmei LI +5 more
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