Results 61 to 70 of about 26,866 (168)

Biodegradable Mg Alloys: Enhancing Anti‐tumor Immunity in Cancer Therapy

open access: yesRare Metals, Volume 45, Issue 4, April 2026.
ABSTRACT Magnesium (Mg) alloys, as biodegradable metallic materials with excellent biocompatibility and mechanical properties, demonstrate significant advantages. In the field of immunotherapy, they present a promising potential option for enhancing therapeutic outcomes and hold broad prospects for application.
Can Feng   +8 more
wiley   +1 more source

Progress of Traditional Chinese Medicine in the treatment of chemotherapy-induced hiccup (肿瘤化疗相关性呃逆的中医治疗进展)

open access: yes中西医结合护理
In people with cancer, certain chemotherapy drugs can have hiccups as a side effect, seriously affecting the quality of life. According to the Traditional Chinese Medicine theory, the chemotherapy-induced hiccup is associated with Zangfu, blood stasis ...
GAO Juan (高娟)   +3 more
doaj   +1 more source

Polydopamine-Functionalized Graphene Oxide: A Versatile Nanocarrier for Chemotherapy and Photothermal Therapy [PDF]

open access: yes, 2015
光热治疗是一种新型的肿瘤治疗技术,与传统的治疗手段相比,其具有独特的优点,如侵入性低、恢复时间短及并发症发生率小,而将光热治疗与传统的化学药物治疗结合在一个体系里,使热和化疗药物同时作用于肿瘤部位,能够更有效的杀死癌细胞。 石墨烯作为一种二维碳纳米材料,具有超高的比面积和强的近红外光吸收能力,在药物输送与光热治疗方面有着潜在的应用价值。然而,目前的研究中,石墨烯主要是通过π-π堆叠和疏水性相互作用装载疏水性药物,无法实现对那些与之无相互作用的亲水性药物的装载 ...
张馨元
core  

Pathomics Signature for Prognosis and CA19‐9 Interception in Pancreatic Ductal Adenocarcinoma: A Real‐Life, Multi‐Center Study

open access: yesAdvanced Science, Volume 13, Issue 16, 18 March 2026.
This study develops a deep learning‐based pathomics model to predict survival outcomes in pancreatic cancer patients. The CrossFormer architecture analyzes routine H&E‐stained tissue slides, identifying key prognostic features including stromal patterns, cellular characteristics, and immune infiltration.
Qiangda Chen   +22 more
wiley   +1 more source

Efficacy of Lithospermum oil gauze wet compress in preventing and treatment of mechanical phlebitis after PICC catheters placement in patients with malignant lymphoma (紫草油纱湿敷防治恶性淋巴瘤患者PICC置管机械性静脉炎的效果观察)

open access: yes中西医结合护理
Objective To investigate the efficacy of Lithospermum oil gauze wet compress in preventing and treatment of mechanical phlebitis caused by peripherally inserted central catheter(PICC) catheters placement in patients with malignant lymphoma.
WANG Shijuan (王石娟)   +5 more
doaj   +1 more source

Tumor‐infiltrating B cells participate in shaping the immunosuppressive microenvironment in solid tumors

open access: yesInternational Journal of Cancer, Volume 158, Issue 5, Page 1156-1165, 1 March 2026.
Abstract Tumor‐infiltrating B cells (TIBs) exhibit dual roles in the tumor microenvironment (TME) of solid tumors. While they can enhance anti‐tumor immunity through antibody production and immune activation, certain subsets—such as regulatory B cells (Bregs) and immunosuppressive plasma cells—contribute to immune evasion by secreting inhibitory ...
Zhitong Li   +5 more
wiley   +1 more source

Nanodrug delivery in reversing multidrug resistance in breast cancer cells [PDF]

open access: yes, 2016
乳腺癌细胞产生多药耐药(Multidrugresistance,MDR)是乳腺癌化疗失败最主要的原因之一,深入研究拮抗或逆转乳腺癌多药耐药有着重要的理论和临床意义。紫杉醇(Paclitaxel,PTX)是目前临床上广泛应用的广谱抗癌药物。临床广泛使用的紫杉醇制剂(商品名“泰素”)毒副反应严重,超敏反应强烈,无明显靶向性,可诱发多药耐药,因此紫杉醇新制剂研究是当前国际国内的热点问题。 本文旨在研制出具有良好临床适应性、可逆转肿瘤多药耐药的紫杉醇纳米制剂,并使其具有磁靶向和光动力治疗的多重功能。首先 ...
王颖君
core  

Preoperative VEGFR‐TKI Plus ICI Therapy Facilitates 3D‐Guided Cytoreductive Nephron‐Sparing Surgical Feasibility and Immune Remodeling in Advanced Renal Cell Carcinoma

open access: yesMed Research, Volume 2, Issue 1, Page 89-105, March 2026.
Preoperative VEGFR‐TKI plus ICI therapy in advanced ccRCC normalizes tumor vasculature, enhances CD8⁺ T/B cell infiltration, and promotes TLS maturation, leading to profound tumor microenvironment remodeling. These immunologic changes improve the feasibility of 3D reconstruction‐guided robotic cytoreductive nephron‐sparing surgery, resulting in reduced
Wenhao Xu   +10 more
wiley   +1 more source

Expression and Clinical Relevance of uPA and ET-1 in Non-small Cell Lung Cancer [PDF]

open access: yes, 2011
Background and objective uPA and ET-1 proteins have been reported to be up-regulated in some of human cancers. The aim of this study is to investigate the alteration and clinical relevance of uPA and ET-1 protein levels in non-small cell lung cancer ...
Boshi WANG   +7 more
core  

Engineering a Tumor‐Targeted MgH2@Lip/PD‐L1 Nanoplatform for Synergistic Hydrogen Therapy and Immune Activation

open access: yesRare Metals, Volume 45, Issue 3, March 2026.
ABSTRACT Lung cancer remains the leading cause of cancer‐related deaths worldwide, yet immune checkpoint blockade (ICB) is often compromised by an immunosuppressive tumor microenvironment (TME) with acidosis, hypoxia, and poor T cell infiltration. Here, we develop a TME‐responsive nanoplatform (MgH2@Lip/PD‐L1) that couples hydrogen gas therapy with PD ...
Xuyu Gu   +5 more
wiley   +1 more source

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