Results 61 to 70 of about 38,945 (161)
Cancer Heterogeneity and Cancer Cell Plasticity: Molecular Mechanisms and Precision Therapy
MedComm, Volume 7, Issue 7, July 2026.Tumor progression is driven by heterogeneity occurring across multiple biological scales. At the molecular level, tumor cells exhibit alterations across distinct omics layers, including genomic mutations, epigenomic reprogramming, transcriptional changes, and proteomic remodeling, collectively shaping tumor cell phenotypes and functional states.
Hanwen Hu +5 more
wiley +1 more source
Rare Metals, Volume 45, Issue 7, July 2026.ABSTRACT Tumor metastasis and recurrence are major reasons for the difficulty in curing cancer. Although some immunotherapy methods have been developed, they are still limited by immunosuppression, resulting in limited therapeutic efficacy against tumors.
Chen Ye +4 more
wiley +1 more source
Research progress of Ruyi Jinhuang Powder in the treatment of pressure injuries (如意金黄散治疗压力性损伤的研究进展)
中西医结合护理Pressure injury (PI) is a common skin problem that occurs most often in patients who are bedridden or have limited mobility, seriously affecting the quality of life of patients.
ZHU Yuxin (朱雨昕) +2 more
doaj +1 more source
, 2004 本发明涉及结构式I和结构式II人参皂苷苷元衍生物3β，12β-二羟-20(21)，24(25)-二烯-达玛烷[dammar-3β，12β-dihydroxyl-20(21)，24(25)-diene，简称Δ20(21)-PPD]和3β，6α，12β-三羟-20(21)，24(25)-二烯-达玛烷[dammar-3β，6α，12β-trihydroxyl-20(21)，24(25)-diene，简称Δ20(21)-PPT]，特别是涉及以Δ20(21)-PPD或和Δ20(21)-PPT以及含有Δ20(21)-
杨凌, 王秀丽, 李鹏, 何克江
core
, 2001 肿瘤转移在肿瘤发展进程中具有十分重要的作用。恶性肿瘤患者很少死于原发癌，绝大多数死于肿瘤转移。目前对于肿瘤转移的机理了解甚少，也缺乏有效的控制和治疗手段。１９９５年Dong犤１犦首次发现的肿瘤转移抑制基因KAI１以及近年来对其机理的研究取得了新进展，研究表明该基因只对肿瘤转移产生抑制作用，而对肿瘤形成没有影响。本文拟就KAI１基因与肿瘤转移抑制的相关性作一综述。１KAI１基因的发现与定位前列腺癌在美国的死亡率较高，其发病率更是高得惊人。在７０－８０岁死于其它原因的男性中，有５０％患有局限性的前列腺肿瘤 ...
张鸣青, 吴乔, 陈玉强
core
中西医结合护理Objective To investigate the effect of Traditional Chinese Medicine (TCM) nursing techniques on improving insomnia symptoms in cancer patients. Methods A literature search was conducted through CNKI, VIP, Wanfang Data, PubMed, Web of Science, Cochrane ...
LIN Haiqing (林海青) +5 more
doaj +1 more source
, 2005 本发明涉及具有抗肿瘤活性的低极性人参皂苷组合物，根据制备方法及其活性特点，将低极性人参皂甙分为七组，本发明特别是涉及二醇I组与其余六组低极性人参皂甙中任何一组或多组低极性人参皂甙的混合物。所述的组合物充分发挥各种低极性人参皂甙的特点，使抗癌活性显著增强，组合物具有诱导肿瘤细胞分化、诱导肿瘤细胞凋亡、抑制肿瘤生长、逆转肿瘤多药耐药性、抑制肿瘤新生血管生成、抑制肿瘤的浸润和转移、增强机体免疫力和降低化疗药物毒副作用等抗肿瘤活性，极具开发潜力 ...
杨凌, 何克江
core
中西医结合护理With the transformation of medical model, patients have higher requirements for clinical nursing services. Humanistic care is the core content of modern nursing, which can enhance the nurse-patient relationship and improve the patient treatment ...
TANG Qian (唐倩) +4 more
doaj +1 more source
, 2016 本发明涉及主动靶向型抗脑肿瘤药物及其制备方法。具体地，本发明公开了一种复合物，所述复合物包括：纳米载体，所述纳米载体的粒径小于200nm；和靶分子，所述靶分子偶联于所述纳米载体的表面，并与血脑屏障上的神经肽受体Y1和脑肿瘤细胞上的神经肽受体Y2均具有高的亲和性。本发明还公开了包含所述复合物的组合物及其制法和用途。所述复合物或所述组合物可有效跨越血脑屏障进入脑部，且可与脑肿瘤细胞高特异性结合，从而将抗肿瘤药物靶向输送至肿瘤细胞内，有效提高细胞内的药物浓度 ...
吴爱国, 田宇辰, 李娟
core
, 2017 目的描述林州地区食管癌、贲门癌患者在住院治疗期间社会支持、焦虑及抑郁状况。方法采用临床心理评定量表中社会支持评价量表(SSRS)、焦虑自评量表(SAS)与抑郁自评表(SDS)对80例食管癌患者,32例贲门癌患者和80例健康对照进行心理调查。结果调查发现,肿瘤患者普遍存在严重的心理问题,食管癌患者焦虑、抑郁发生率分别为31.25%、85.00%,焦虑及抑郁得分为(42.03±9.83)分、(61.78±8.56)分,贲门癌患者焦虑、抑郁发生率为43.80%、93.80 ...
管晨滔 +8 more
core +1 more source