Results 61 to 70 of about 2,409 (117)

NF-KappaB65380;p38 MAPK和JNK通路在运动神经损伤 引起的大鼠病理性疼痛中的作用及机制

Zhongshan Daxue xuebao. Yixue kexue ban, 2009
【目的】 探讨肿瘤坏死因子α(TNF-α)激活的下游信号转导途径-核转录因子kappaB (NF-κB)65380; JNK和p38 MAPK是否参与运动神经损伤引起的大鼠病理性疼痛的形成,并探讨其可能机制65377;【方法】 采用痛行为学测试和免疫荧光组织化学方法,观察鞘内注射NF-κB 抑制剂(PDTC)65380; p38 MAPK 抑制剂(SB203580)和JNK 抑制剂(SP600125)对腰5脊神经前根切断(L5-VRT)大鼠机械性痛过敏及腰5背根神经节(DRG)内电压门控钠通道(Nav1.
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迷走背核的中枢传入来源及其肽能递质

Zhongshan Daxue xuebao. Yixue kexue ban, 1990
用辣根过氧化物酶(HRP)逆行结合免疫组化定位的双标法,观察大鼠迷走背核(DMN)的中枢传入来源和位于这些神经通路的肽能递质。(1)将麦芽凝集素结合HRP(WGA-HRP)注入DMN脑区后,见HRP逆行标记细胞位于:①脑干:孤束核、三叉神经脊束核、小细胞网状核、外侧网状核、中缝隐核、中缝苍白核、臂旁核、被盖背核及蓝斑;②边缘前脑:下丘脑室旁核(PVH)、杏仁中央核、终纹床核和岛叶皮质(IC)。(2)部分切片继续进行免疫组化反应,观察HRP和肽共存的双标细胞。在PVH的尾侧部见辣根过氧化物酶-催产素 ...
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白细胞介素６参与介导大鼠运动神经损伤所致的病理性疼痛

Zhongshan Daxue xuebao. Yixue kexue ban, 2012
【目的】 检测选择性切断腰５脊神经前根（Ｌ５-ＶＲＴ）术后脊髓背角内ＩＬ-６的异常表达并评价其对运动神经损伤所致机械性痛觉过敏的影响。【方法】 在不损伤感觉传入的情况下，Ｌ５-ＶＲＴ制备大鼠机械性痛过敏模型，采用Ｗｅｓｔｅｒｎ ｂｌｏｔ和免疫荧光组织化学方法检测ＩＬ-６在脊髓背角的表达水平并进行细胞定位，通过痛行为学测试观察蛛网膜下腔内注射ＩＬ-６中和抗体对Ｌ５-ＶＲＴ 大鼠机械性痛过敏的影响。分组：ｓｈａｍ组、Ｌ５-ＶＲＴ组，ｎ ＝ ５；ｖｅｈｉｃｌｅ＋ Ｌ５-ＶＲＴ、ＩＬ-６ ...
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[Temporal changes of chronic postsurgical pain in mice: the regulatory role of CX3CL1 in the dorsal root ganglion]. [PDF]

Nan Fang Yi Ke Da Xue Xue Bao
Zhao B, Lü Z, Ji D, Tian S, Wu Y, Li X, Zhou J, Fang J, Liang Y.   +8 more
europepmc   +1 more source

[Effectiveness comparison of transforaminal endoscopy and unilateral biportal endoscopy for far lateral lumbar disc herniation]. [PDF]

Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi
Zhang J, Feng B, Xu Z, Tian L, Dai G, Wang K, Hu P.   +6 more
europepmc   +1 more source

[Effectiveness of all-arthroscopic gastrocnemius aponeurosis release and Achilles tendon insertion debridement in treatment of Haglund's disease]. [PDF]

Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi
Jia R, Xue Y, Kong D, Zhang Y, Sun G.
europepmc   +1 more source

[Rehabilitation guidelines and specifications for traumatic spinal cord injury (2025 edition)]. [PDF]

Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi
Professional Committee Of Spine And Spinal Cord Injury Rehabilitation China Association Of Rehabilitation Of Disabled Persons, Professional Committee Of Spine Chinese Association Of Rehabilitation Medicine, The Second Medical-Rehabilitation Integration Working Committee Chinese Association Of Rehabilitation Medicine, Spine And Spinal Cord Injury Repair Study Group The Third Professional Committee Of Neurorestoratology Chinese Medical Doctor Association.   +3 more
europepmc   +1 more source

[State-of-the-art in peripheral nerve injury diagnosis and therapy]. [PDF]

Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi
Sun J, Chen L.
europepmc   +1 more source

[Risk factor analysis of excessive resection of facet joint after large-channel spinal endoscopic depression for degenerative lumbar diseases]. [PDF]

Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi
Yan T, Zeng J, Lin X, Li T, Wu C.
europepmc   +1 more source

[Clinical study on functional perforator flap with sensory reconstruction for repairing complex defects on limbs]. [PDF]

Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi
Tang L, Huang S, Zhang J, Zhou X.
europepmc   +1 more source