Results 21 to 30 of about 3,952 (169)

Multiple pregnancy with complete hydatidiform mole and coexisting normal fetus: systematic review and meta‐analysis of clinical outcomes from non‐randomized studies

open access: yesUltrasound in Obstetrics &Gynecology, Volume 67, Issue 3, Page 272-282, March 2026.
ABSTRACT Objective Complete hydatidiform mole and coexisting normal fetus (CHMCF) is a rare condition for which there is significant heterogeneity in diagnosis, counseling and management of complications. The objective of this study was to summarize the prevalence of clinical outcomes in reported cases of CHMCF.
N. Salmeri   +8 more
wiley   +1 more source

Relationship between abnormal symptoms of Prader-Willi syndrome model --Snord116 deletion mice and Ghrelin signaling pathway [PDF]

open access: yes, 2016
Prader–Willi综合症是以进食异常和血液Ghrelin异常升高为特征的遗传肥胖症。其病因是Snord116SnoRNA群的表达缺失。我们构建的Snord116del小鼠模型表现出贪食和血液Ghrelin升高等PWS症状。此次研究中,我们繁育野生型(WT)、Snord116del(SW)、Ghrl-/-(WG)、Ghsr-/-(WR)小鼠,并制备[Snord116del,Ghrl-/-](SG)和[Snord116del,Ghsr-/-](SR)双敲除小鼠,对其生长发育 ...
甘利芬
core  

胎儿肠扭转的产前超声诊断及临床预后探讨 [PDF]

open access: yes, 2021
目的探讨胎儿肠扭转的产前超声特征及临床预后。方法回顾性分析2017年6月至2021年3月在广东省妇幼保健院超声科进行产前超声检查、超声提示肠扭转或产后证实肠扭转的17例胎儿的超声表现及临床资料,以肠管扩张合并漩涡征或血管螺旋征为诊断肠扭转的标准,并随访胎儿出生后手术病理或引产后尸体解剖结果,追踪其临床预后。结果17例孕妇年龄介于24~40岁,中位数29(26~33)岁;初次诊断肠扭转的孕周介于24~33周,中位数26(24~31)周。17例胎儿在妊娠过程中均出现肠管扩张,16例存在漩涡征 ...
万志彬   +7 more
core   +1 more source

Fetoscopic laser ablation vs standard management for Type‐II and Type‐III vasa previa

open access: yesUltrasound in Obstetrics &Gynecology, Volume 67, Issue 3, Page 320-328, March 2026.
ABSTRACT Objective The standard management (SM) for vasa previa (VP) includes antepartum inpatient admission at 28–32 weeks' gestation followed by Cesarean delivery at 34–37 weeks. Case reports and case series have reported on fetoscopic laser ablation (FLA) as an alternative management approach for Types‐II and ‐III VP.
S. Backley   +11 more
wiley   +1 more source

The establishment of Elispot-based neutralization assay for HCMV and its application in epidemiological study [PDF]

open access: yes, 2013
人巨细胞病毒(humancytomegalovirus,HCMV)的感染在全球普遍存在。HCMV感染一般以潜伏状态存在,当机体免疫力低下时,则易发生再激发感染,引起严重甚至威胁生命的感染性疾病。在自然感染过程中,HCMV可感染包括淋巴细胞,上皮细胞以及内皮细胞在内的多种类型的细胞。HCMV体外培养体系的宿主细胞主要是上皮细胞及成纤维细胞。传统的基于细胞病变的TCID50以及空斑形成减少实验检测样本中和滴度的方法,存在周期长,操作繁杂,主观因素影响大的缺点,不适合大样本量的临床研究 ...
赵利利
core  

Cost–benefit analysis of first‐trimester pre‐eclampsia screening: comparison of multivariable Gaussian algorithm with and without placental growth factor

open access: yesUltrasound in Obstetrics &Gynecology, Volume 67, Issue 2, Page 162-167, February 2026.
ABSTRACT Objective Pre‐eclampsia (PE) is a leading cause of maternal and neonatal morbidity and mortality worldwide. Early identification of high‐risk pregnancies in the first trimester allows preventive treatment with low‐dose aspirin. This study aimed to evaluate whether multivariable Gaussian algorithm‐based PE screening strategies, with and without
E. Bonacina   +10 more
wiley   +1 more source

乙肝病毒携带者孕妇胎盘病理学

open access: yesZhongshan Daxue xuebao. Yixue kexue ban, 2002
【目的】通过了解胎盘病理变化与胎儿感染HBV 的关系, 探讨胎儿感染的机理。【方法】测量160 例足月妊娠 孕妇胎盘大小、质量、脐长, 并进行大体病理学检查。分组包括30 例胎儿感染组、胎儿血指标阴性者80 例为阴性对照组、正常 孕妇50 例为正常组。对其中61 例HBV 携带者孕妇胎盘进行详细的组织病理学观察(包括胎儿感染组28 例及对照组33 例), 分级诊断分析, 用PCR、ELISA 法检测胎儿血HBV DNA 和HBsAg 。【结果】①胎儿感染组平均胎盘体积为(638 ±179 ...
刘颖琳, 刘新质
doaj  

内分泌扰乱化学品对动物的影响和作用机制 [PDF]

open access: yes, 2000
介绍了内分泌扰乱化学品 (EDCs)的作用机制及其对野生动物影响的研究进展。内分泌化学品可能与性激素受体、甲状腺素受体和其他受体 (如芳烃受体 )结合 ,也可能通过影响动物体内激素的代谢而对动物的生长发育起调控作用。各实验室的重复实验不支持环境雌激素之间存在协同作用的结论。已报道过的人体和野生动物生殖缺陷中具有充分证据的暴露 -效应关系的实例为数不多。尽管野生鱼类变性是英国河流中的一个普遍现象 ,但进一步的实验证明污水处理场出水中的天然和合成雌激素足以引起鱼类的变性反应 ...
邱东茹,吴振斌,贺锋
core  

Undetected cases after implementation of first‐trimester anomaly scan in low‐risk population: insights from the IMITAS study

open access: yesUltrasound in Obstetrics &Gynecology, Volume 67, Issue 1, Page 27-33, January 2026.
ABSTRACT Objective To assess the effectiveness of the first‐trimester anomaly scan (FTAS) performed as part of a centrally steered national screening program in The Netherlands by investigating false‐negative cases with a fetal structural anomaly that was not detected at the FTAS.
K. Bronsgeest   +18 more
wiley   +1 more source

Generation and Characterization of HCMV Specific Human Antibody to Explore Antibody Response Profile in HCMV Naturally Infected Individuals [PDF]

open access: yes, 2015
人巨细胞病毒(Humancytomegalovirus,HCMV)是一种常见的疱疹病毒,在人群中普遍感染,儿童感染率约为10%-40%,成人为50%-90%,大部分感染者为无临床症状的健康人。但机体免疫功能低下的人群如器官移植患者及AIDS病人,更易发生HCMV病毒的新发或复发感染,引起致命疾病如肺炎、肝炎、脑炎等,从而导致器官移植失败及术后死亡;同时HCMV病毒也是宫内感染中危害最大的病毒之一,感染率占怀孕妇女的0.5%-2%,尤其是在发展中国家较为常见,孕妇感染后自身多无明显症状或轻微症状 ...
夏琳
core  

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