Results 31 to 40 of about 1,390 (162)
胎盘植入是一种异常的胎盘附着形式,是导致产妇产后大出血的主要原因之一。近年来,随着剖宫产率的增高,胎盘植入(placenta accrete)的发生率也逐渐升高。广义的胎盘植入根据胎盘绒毛侵入子宫肌层深度分为3类:粘连性胎盘植入(placenta accrete vera)、植入性胎盘植入(placenta increta)、穿透性胎盘植入(placenta perccreta)[1 ...
姚立英, 李增彦
doaj
ABSTRACT Objective A soluble fms‐like tyrosine kinase‐1 (sFlt‐1)‐to‐placental growth factor (PlGF) ratio cut‐off of 38 is currently considered optimal for ruling out pre‐eclampsia (PE); however, implementation of this ratio in clinical practice is limited.
M. N. Nan +15 more
wiley +1 more source
Effect of Neu5Ac supplementation on learning and memory in weanling rats and rat pups [PDF]
研究背景:新生儿生长发育对营养物质有特殊的要求,任何营养素的匮乏对机体的正常生长和器官结构功能的发育都有深远影响,对脑发育的影响尤为重要。早期营养对大脑的结构和功能有着不可逆转的影响,一旦错过大脑发育的关键期,产生的缺陷后天将无法弥补。新生儿期营养素的缺乏会影响其认知功能。 N-乙酰神经氨酸(N-acetylneuraminicacids,Neu5Ac)是人体中最常见的唾液酸。Neu5Ac在人体中普遍存在,在脑组织及母乳中含量较高;唾液酸作用于神经元细胞膜及突触,在神经系统中产生重要作用 ...
卞冬生
core
ABSTRACT Objective Globally, one in four pregnant women is classified as overweight or obese, based on their prepregnancy body mass index (BMI). Obese pregnant women are at increased risk of adverse pregnancy outcomes and long‐term cardiovascular disease that occurs earlier in life.
M. Charakida +6 more
wiley +1 more source
【目的】通过了解胎盘病理变化与胎儿感染HBV 的关系, 探讨胎儿感染的机理。【方法】测量160 例足月妊娠 孕妇胎盘大小、质量、脐长, 并进行大体病理学检查。分组包括30 例胎儿感染组、胎儿血指标阴性者80 例为阴性对照组、正常 孕妇50 例为正常组。对其中61 例HBV 携带者孕妇胎盘进行详细的组织病理学观察(包括胎儿感染组28 例及对照组33 例), 分级诊断分析, 用PCR、ELISA 法检测胎儿血HBV DNA 和HBsAg 。【结果】①胎儿感染组平均胎盘体积为(638 ±179 ...
刘颖琳, 刘新质
doaj
Prediction of pre‐eclampsia using maternal hemodynamic parameters at 12 + 0 to 15 + 6 weeks
ABSTRACT Objectives To compare the maternal hemodynamic profile at 12 + 0 to 15 + 6 weeks' gestation in women who subsequently developed pre‐eclampsia (PE) and those who did not, and to assess the screening performance of maternal hemodynamic parameters for PE in combination with the Fetal Medicine Foundation (FMF) triple test, including maternal ...
X. Wang +9 more
wiley +1 more source
Functions of Periostin in pre-metastatic immunosuppressive niches of breast tumor metastasis [PDF]
在肿瘤发生发展过程中,肿瘤细胞及其相关间质细胞向肿瘤微环境中分泌大量促癌细胞因子以及趋化因子,促使骨髓来源的免疫抑制细胞(myeloid-derivedsuppressorcells,MDSCs)向远处靶器官浸润,形成免疫抑制微环境,为肿瘤细胞的转移提供有利条件,从而促进肿瘤细胞的转移。在乳腺癌肿瘤组织中,细胞外基质蛋白Periostin主要由肿瘤相关成纤维细胞分泌,并参与调控肿瘤的发生发展过程。然而,关于Periostin蛋白在MDSCs介导的转移前微环境形成中的功能尚不清楚 ...
熊珊珊
core
ABSTRACT Objective Accurate differentiation between placenta accreta spectrum (PAS) and uterine‐scar dehiscence with underlying non‐adherent placenta is often challenging, even for PAS experts, both prenatally and intraoperatively. We investigated the use of standardized two‐dimensional grayscale ultrasound and Doppler imaging markers in ...
T. Adu‐Bredu +3 more
wiley +1 more source
ABSTRACT Objective To compare the diagnostic performance of different manufacturers' immunoassays for the soluble fms‐like tyrosine kinase‐1 (sFlt‐1)‐to‐placental growth factor (PlGF) ratio with that of a point‐of‐care (PoC) test for glycosylated fibronectin (GlyFn) in women with suspected pre‐eclampsia (PE).
I. Y. M. Wah +7 more
wiley +1 more source
Study on the effects of down-regulating Annexin A3 expression on biological behaviors of lung adenocarcinoma and its molecular mechanism [PDF]
肺癌是我国第一大癌症,其发病率和死亡率均居恶性肿瘤之首,严重危害人类健康。肺癌按组织学类型可分为鳞癌、腺癌、小细胞癌和大细胞癌。近年来,肺腺癌(lungadenocarcinoma,AdC)的发病率呈逐步上升趋势,且患者死亡率高、预后极差。癌细胞易转移是肺腺癌患者预后差的主要原因,因此,探寻肺腺癌转移的分子机制及其新的治疗靶标,对于提高肺腺癌患者预后意义重大。我们前期研究中,采用定量蛋白质组学技术鉴定出AnnexinA3(Anxa3)为一个新的肺腺癌转移相关分子 ...
刘青青
core

