Isatis tinctoria L. combined with costimulatory molecules blockade prolongs survival of cardiac allografts in alloantigen-primed mice [PDF]
, 2011 目的：这项研究的目标一是检测板蓝根化合物K对异型抗原预致敏小鼠脾脏中记忆性T细胞的体外同种反应性增殖强度的影响，目标二是检测K与效应性T细胞共刺激阻断剂联用，对二次同种异体心脏移植物存活时间的影响。目标三是探讨化合物K对二次同种异体心脏移植物可能的保护机制。 方法：皮肤移植小鼠再次心脏移植构建小鼠预致敏同种异体心脏移植模型，后联合应用板蓝根化合物K和共刺激通路阻断剂，观察移植物生存期的改变，并从记忆性T细胞和记忆性B细胞两个角度探讨其可能的作用机制。 结果：1、在体外试验中 ...
康向朋
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Study on the Effects and Mechanisms of Recombinant Human Prothymosin α in Metabolism of Glucose and Lipid [PDF]
, 2010 目前，人们正越来越多地食用高糖高脂食品。大量临床研究表明，长期食用高糖高脂食品将引起肥胖症，而肥胖将导致机体糖耐量作用下降，引发胰岛素抵抗，最终诱发2型糖尿病。更为严重的是，糖尿病将引发如酮症酸中毒、脑血管疾病、肾病等其它并发症。如何预防和治疗糖尿病及其并发症已经成为医学界关注的焦点。糖尿病的基本特征是胰岛β细胞的结构和功能受损，导致机体胰岛素分泌不足。依赖外供给胰岛素是目前主要的治疗方案，然而通过防止胰岛β细胞凋亡和促进胰岛β细胞分裂的角度进行研究，将是预防和治疗糖尿病的新途径。 经研究证实 ...
吴汉洲
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Zhongshan Daxue xuebao. Yixue kexue ban, 1994 低剂量重组人类生长激素（ＨＧＨ）与人类绝经期促性腺激素（ＨＭＧ）合用于体外受精与胚胎移植（ＩＶＦ－ＥＴ）超排卵周期中，反应欠佳的不育患者，发现能促进卵子成熟，提高受精率，增加移植胚胎数。明显改善妊娠率，但未能影响卵泡的增补及减少诱发排卵所需ＨＭＧ的剂量和用药时间。血清ＩＧＦ－１水平在使用外源性生长激素（ＧＨ）期间明显升高，而对照组无类似变化，证实低剂量ＧＨ在本研究中的使用是有效的。
doaj
[Research progress on the donor cell sources of pancreatic islet transplantation for treatment of diabetes mellitus]. [PDF]
Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi, 2018 Zhu H +7 more
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Mesenchymal stem cell conditioned medium improves hypoxic injury to protect islet graft function. [PDF]
Zhong Nan Da Xue Xue Bao Yi Xue BanChen J +6 more
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[A Study on the Association Between Various Insulin Resistance Assessment Indices and IVF-ET Outcomes in Patients With Polycystic Ovary Syndrome]. [PDF]
Sichuan Da Xue Xue Bao Yi Xue BanLiu Y, Hu Z, Han J, Gao R, Qin L.
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[Recent Research Progress and Prospects on Periodontitis Affecting Systemic Comorbidities via the Oral-Gut Axis]. [PDF]
Sichuan Da Xue Xue Bao Yi Xue BanZhang S, Li Y, Yang Z, Huang H, Pan Y.
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[Research advances in neuromodulation techniques for blood glucose regulation and diabetes intervention]. [PDF]
Sheng Wu Yi Xue Gong Cheng Xue Za Zhi, 2023 Liu H, Wang W.
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[Human umbilical cord mesenchymal stem cell grafting alleviates inflammatory response in type 1 diabetic mice by suppressing M1 macrophage polarization through Chi3l1]. [PDF]
Nan Fang Yi Ke Da Xue Xue BaoLiu X, Xu Y, Sheng H, Liu H.
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[Research progress on the multidimensional regulation of gut microbiota on metabolism, immunity, and inflammatory response in metabolic associated fatty liver disease]. [PDF]
Zhonghua Gan Zang Bing Za ZhiWu ST, Lu XL.
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