Results 21 to 30 of about 3,888 (160)

Impact on glucometric variables and quality of life of the advanced hybrid closed‐loop system in pediatric and adolescent type 1 diabetes 高级混合闭环系统对儿童和青少年1型糖尿病患者血糖指标和生活质量的影响

Journal of Diabetes, Volume 15, Issue 8, Page 699-708, August 2023., 2023
Highlights This study is the first to evaluate the efficacy of the closed‐loop system MiniMed 780G in children aged 6 to 17 years with type 1 diabetes previously receiving continuous subcutaneous insulin infusion and intermittent continuous glucose monitoring. This shows early results, with improvement in time in range and all hyperglycemia times, from
Alfonso Lendínez‐Jurado, Ana Gómez‐Perea, Ana B. Ariza‐Jiménez, Leopoldo Tapia‐Ceballos, Icía Becerra‐Paz, María F. Martos‐Lirio, Fernando Moreno‐Jabato, Isabel Leiva‐Gea   +7 more
wiley   +1 more source

A Review of micro RNAs changes in T2DM in animals and humans miRNAs在2型糖尿病人类和动物中的变化

Journal of Diabetes, Volume 15, Issue 8, Page 649-664, August 2023., 2023
Highlights MicroRNAs (miRNAs) are overexpressed in inflammation, insulin resistance, and type 2 diabetes mellitus (T2DM). Many types of miRNAs are changed during the T2DM progression. miRNAs have a potential role as a biomarker in T2DM diagnosis. Abstract Type 2 diabetes mellitus (T2DM) and its associated complications have become a crucial public ...
Mohammad Reza Afsharmanesh, Zeinab Mohammadi, Azad Reza Mansourian, Seyyed Mehdi Jafari   +3 more
wiley   +1 more source

DiabetesWise: An innovative approach to promoting diabetes device awareness Diabetes wise:提高糖尿病器械认知度的创新方法

Journal of Diabetes, Volume 15, Issue 7, Page 597-606, July 2023., 2023
Highlights About a third of participants requested diabetes device prescriptions with 3 months of being invited to interact with DiabetesWise. Many factors predicted prior CGM use but diabetes distress was the only predictor of requesting a prescription after interacting with DiabetesWise.
Jessie J. Wong, Ananta Addala, Sarah J. Hanes, Sara Krugman, Diana Naranjo, Sierra Nelmes, Kyle Jacques Rose, Molly L. Tanenbaum, Korey K. Hood   +8 more
wiley   +1 more source

Relative contributions of fasting and postprandial glucose increments, glycemic variability, and non‐glycemic factors to HbA1c in individuals with type 1 diabetes 基于1型糖尿病患者的空腹和餐后血糖增量、血糖变异性和非血糖因素对HbA1C的相对贡献

Journal of Diabetes, Volume 15, Issue 6, Page 465-473, June 2023., 2023
Highlights Evidence for contribution of basal and postprandial glucose increments and glycemic variability to glycated hemoglobin (HbA1c) among adults with type 1 diabetes (T1D) is limited. In this study, after analyzing a total of 169 550 sensor‐derived data in 2409 meals recorded from 102 T1D adults, we found that basal hyperglycemia (BHG) was four ...
Yongwen Zhou, Mao Zheng, Hongrong Deng, Xueying Zheng, Sihui Luo, Daizhi Yang, Xiaodong Mai, Wen Xu, Jinhua Yan, Jianping Weng   +9 more
wiley   +1 more source

β‐Cell glucokinase expression was increased in type 2 diabetes subjects with better glycemic control 血糖控制较好的2型糖尿病患者β细胞葡萄糖激酶表达增加

Journal of Diabetes, Volume 15, Issue 5, Page 409-418, May 2023., 2023
Highlights A significant upregulation of glucokinase (GCK) expression was found in type 2 diabetes (T2D) subjects with adequate glucose control, but such increase was undetected in T2D with poor glycemic control. A strong positive correlation between GCK levels and spliced X‐box binding protein 1 (XBP1s)/activating transcription factor 4 (ATF4 ...
Jingwen Liu, Hui Fu, Fuyun Kang, Guang Ning, Qicheng Ni, Weiqing Wang, Qidi Wang   +6 more
wiley   +1 more source

Effects of neprilysin and neprilysin inhibitors on glucose homeostasis: Controversial points and a promising arena 脑啡肽酶和脑啡肽酶抑制剂对葡萄糖稳态的影响:一个有争议的观点和有前景的领域

Journal of Diabetes, Volume 15, Issue 5, Page 397-408, May 2023., 2023
Highlights Neprilysin (NEP) inhibitors may lead to beneficial effects through inhibition of NEP, which involves impairment of glucose homeostasis through modulation of insulin resistance and the development of pancreatic β cell dysfunction as observed in type 2 diabetes mellitus.
Faisal Holil AlAnazi, Hayder M. Al‐kuraishy, Ali I. Al‐Gareeb, Athanasios Alexiou, Marios Papadakis, Hanan A. Ogaly, Yousef Abud Alanazi, Hebatallah M. Saad, Gaber El‐Saber Batiha   +8 more
wiley   +1 more source

Sleeve gastrectomy improved microvascular phenotypes from obesity cohort, detected with optical coherence tomography angiography 通过光学相干断层扫描血管成像检测发现袖状胃切除术改善肥胖队列的微血管表型

Journal of Diabetes, Volume 15, Issue 4, Page 313-324, April 2023., 2023
Highlights Different microvascular phenotypes were detected by noninvasive optical coherence tomography angiography (OCTA) in metabolically healthy obesity and metabolic syndrome patients. Baseline blood pressure and insulin status may be key determinants for vascular benefit from bariatric surgery.
Yaying Chen, Yanyang Liu, Lin Cong, Ailin Liu, Xiangyuan Song, Wenting Liu, Rong Hua, Qiwei Shen, Yikai Shao, Yiwen Xue, Qiyuan Yao, Yuyan Zhang   +11 more
wiley   +1 more source

Development and validation of risk prediction models for large for gestational age infants using logistic regression and two machine learning algorithms 使用Logistic回归和两种机器学习算法开发和验证大于胎龄儿风险预测模型

Journal of Diabetes, Volume 15, Issue 4, Page 338-348, April 2023., 2023
Highlights The logistic regression model consisted of seven commonly used clinical indicators (including lipid profile) and gestational diabetes mellitus subtypes, with an area under the curve (AUC) of 0.760 for the training set and 0.748 for the internal validation set.
Ning Wang, Haonan Guo, Yingyu Jing, Yifan Zhang, Bo Sun, Xingyan Pan, Huan Chen, Jing Xu, Mengjun Wang, Xi Chen, Lin Song, Wei Cui   +11 more
wiley   +1 more source

U‐shaped association between serum IGF2BP3 and T2DM: A cross‐sectional study in Chinese population 血清IGF2BP3与2型糖尿病的U型关联:一项中国人群横断面研究

Journal of Diabetes, Volume 15, Issue 4, Page 349-361, April 2023., 2023
Highlights This is the first cross‐sectional study of the association between serum IGF2BP3 levels and odds of T2DM in high‐risk Chinese population. Two upregulated (IGF2BP2 and IGF2BP3) and 5 downregulated (METTL3, ALKBH1, YTHDF2, YTHDF3, and HNRNPC) m6A‐related genes could contribute to the occurrence of T2DM.
Xiaoying Wu, Wei Wang, Shujin Fan, Lili You, Feng Li, Xiaoyun Zhang, Hongshi Wu, Juying Tang, Yiqin Qi, Wanting Feng, Li Yan, Meng Ren   +11 more
wiley   +1 more source

Study on the mechanism of FBXW7 protects against insulin resistance via regulating FetuinA protein level [PDF]

, 2016
目的：FBXW7属于SCF类泛素连接酶E3，可调控脂质代谢关键转录因子和胰岛功能相关蛋白的泛素化降解。FetuinA是一类参与机体糖脂代谢调控的重要肝脏因子，与胰岛素抵抗发生密切相关，但在肥胖状态下肝脏中蛋白水平异常升高机制不得而知。本研究拟探究FBXW7在肥胖状态下对FetuinA蛋白水平调节机制，有助于进一步完善肥胖致胰岛素抵抗机制。 方法：本课题结合高脂饮食诱导的HFD肥胖小鼠模型和正常饮食诱导的ob/ob小鼠肥胖模型，检测小鼠糖脂代谢相关指标，采用Real-timePCR和ELISA ...
刘祺
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