Results 31 to 40 of about 324,602 (155)

DiabetesWise: An innovative approach to promoting diabetes device awareness Diabetes wise:提高糖尿病器械认知度的创新方法

open access: yesJournal of Diabetes, Volume 15, Issue 7, Page 597-606, July 2023., 2023
Highlights About a third of participants requested diabetes device prescriptions with 3 months of being invited to interact with DiabetesWise. Many factors predicted prior CGM use but diabetes distress was the only predictor of requesting a prescription after interacting with DiabetesWise.
Jessie J. Wong   +8 more
wiley   +1 more source

Relative contributions of fasting and postprandial glucose increments, glycemic variability, and non‐glycemic factors to HbA1c in individuals with type 1 diabetes 基于1型糖尿病患者的空腹和餐后血糖增量、血糖变异性和非血糖因素对HbA1C的相对贡献

open access: yesJournal of Diabetes, Volume 15, Issue 6, Page 465-473, June 2023., 2023
Highlights Evidence for contribution of basal and postprandial glucose increments and glycemic variability to glycated hemoglobin (HbA1c) among adults with type 1 diabetes (T1D) is limited. In this study, after analyzing a total of 169 550 sensor‐derived data in 2409 meals recorded from 102 T1D adults, we found that basal hyperglycemia (BHG) was four ...
Yongwen Zhou   +9 more
wiley   +1 more source

β‐Cell glucokinase expression was increased in type 2 diabetes subjects with better glycemic control 血糖控制较好的2型糖尿病患者β细胞葡萄糖激酶表达增加

open access: yesJournal of Diabetes, Volume 15, Issue 5, Page 409-418, May 2023., 2023
Highlights A significant upregulation of glucokinase (GCK) expression was found in type 2 diabetes (T2D) subjects with adequate glucose control, but such increase was undetected in T2D with poor glycemic control. A strong positive correlation between GCK levels and spliced X‐box binding protein 1 (XBP1s)/activating transcription factor 4 (ATF4 ...
Jingwen Liu   +6 more
wiley   +1 more source

Effectiveness, safety, initial optimal dose, and optimal maintenance dose range of basal insulin regimens for type 2 diabetes: A systematic review with meta‐analysis 基础胰岛素治疗2型糖尿病的有效性、安全性、初始最佳剂量和最佳维持剂量范围:一项meta分析的系统综述

open access: yesJournal of Diabetes, Volume 15, Issue 5, Page 419-435, May 2023., 2023
Highlights This is a systematic review and meta‐analysis. MEDLINE, EMBASE, Web of Science, and the Cochrane Library were searched from January 2000 to February 2022. Among 11,163 citations retrieved, 35 publications met the pre‐planned criteria. The five basal insulins are effective for insulin‐naive adult patients with T2DM. Glargine U‐300, degludec U‐
Yingying Luo   +20 more
wiley   +1 more source

Effects of neprilysin and neprilysin inhibitors on glucose homeostasis: Controversial points and a promising arena 脑啡肽酶和脑啡肽酶抑制剂对葡萄糖稳态的影响:一个有争议的观点和有前景的领域

open access: yesJournal of Diabetes, Volume 15, Issue 5, Page 397-408, May 2023., 2023
Highlights Neprilysin (NEP) inhibitors may lead to beneficial effects through inhibition of NEP, which involves impairment of glucose homeostasis through modulation of insulin resistance and the development of pancreatic β cell dysfunction as observed in type 2 diabetes mellitus.
Faisal Holil AlAnazi   +8 more
wiley   +1 more source

Sleeve gastrectomy improved microvascular phenotypes from obesity cohort, detected with optical coherence tomography angiography 通过光学相干断层扫描血管成像检测发现袖状胃切除术改善肥胖队列的微血管表型

open access: yesJournal of Diabetes, Volume 15, Issue 4, Page 313-324, April 2023., 2023
Highlights Different microvascular phenotypes were detected by noninvasive optical coherence tomography angiography (OCTA) in metabolically healthy obesity and metabolic syndrome patients. Baseline blood pressure and insulin status may be key determinants for vascular benefit from bariatric surgery.
Yaying Chen   +11 more
wiley   +1 more source

Development and validation of risk prediction models for large for gestational age infants using logistic regression and two machine learning algorithms 使用Logistic回归和两种机器学习算法开发和验证大于胎龄儿风险预测模型

open access: yesJournal of Diabetes, Volume 15, Issue 4, Page 338-348, April 2023., 2023
Highlights The logistic regression model consisted of seven commonly used clinical indicators (including lipid profile) and gestational diabetes mellitus subtypes, with an area under the curve (AUC) of 0.760 for the training set and 0.748 for the internal validation set.
Ning Wang   +11 more
wiley   +1 more source

U‐shaped association between serum IGF2BP3 and T2DM: A cross‐sectional study in Chinese population 血清IGF2BP3与2型糖尿病的U型关联:一项中国人群横断面研究

open access: yesJournal of Diabetes, Volume 15, Issue 4, Page 349-361, April 2023., 2023
Highlights This is the first cross‐sectional study of the association between serum IGF2BP3 levels and odds of T2DM in high‐risk Chinese population. Two upregulated (IGF2BP2 and IGF2BP3) and 5 downregulated (METTL3, ALKBH1, YTHDF2, YTHDF3, and HNRNPC) m6A‐related genes could contribute to the occurrence of T2DM.
Xiaoying Wu   +11 more
wiley   +1 more source

肠促胰素在PCOS中的作用和机制 [PDF]

open access: yes, 2022
肠道菌群与疾病的关系为近年研究热点之一,肠-脑轴可能参与肥胖、糖尿病、多囊卵巢综合征(PCOS)等代谢相关疾病的发病机制。肠道菌群种类数量庞大,肠-脑轴的神经分泌调节机制尚不清楚,肠道菌群影响下丘脑-垂体-卵巢轴(HPO)的作用靶点难以准确定位。肠道内分泌激素近期受到关注,肠促胰素包括胰高血糖素样肽-1(GLP-1)和葡萄糖依赖性促胰岛素多肽(GIP)。这两种肠源性激素均可促进胰岛素的释放并降低血糖。目前国内外有关肠促胰素与HPO轴的研究较少,肠促胰素对PCOS的影响尚不明确。本文将综述该领域的研究进展,
李琳, 潘孟茹
core   +1 more source

复方威灵仙颗粒对高尿酸血症患者血尿酸和胰岛素抵抗的影响 [PDF]

open access: yes, 2017
目的观察复方威灵仙颗粒对高尿酸血症(HUA)患者血尿酸(UA)临床疗效及胰岛素抵抗的影响。方法 HUA患者63例,随机分成复方威灵仙颗粒组31例和别嘌呤醇组32例,在基础治疗的基础上,分别给予复方威灵仙颗粒(1剂/d,2次/d)及别嘌呤醇片(100 mg/次,3次/d),8 w为1个疗程。观察治疗前后血UA及临床疗效、空腹血糖(FPG)、空腹胰岛素(FINS)及胰岛素抵抗指数。结果复方威灵仙颗粒组与别嘌呤醇组治疗后的血UA均较治疗前有明显下降(P〈0.01),治疗总有效率分别为86.7%与90 ...
冯桂贞, 吕崇山, 罗艾君
core   +1 more source

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