目的探讨白细胞介素1A(IL-1A)多态性与神经胶质瘤的相关性。方法采用聚合酶链反应-限制性片段长度多态性检测154例神经胶质瘤患者和195例正常对照组IL-1A多态性。结果 IL-1A+4845G/T位点:与GG基因型相比,GT/TT基因型显著增加了神经胶质瘤的发病风险(GT/TT与GG相比:χ2=5.94,P=0.015)。与G等位基因相比,T等位基因显著增加了神经胶质瘤的发病风险(χ2=5.97,P=0.015)。未发现IL-1A-889C/T多态性频率分布在对照组和神经胶质瘤组之间存在显著差异 ...
岩亮, 舒云
doaj
目的观察苯乙酸(PA)诱导分化胶质瘤细胞C6过程中,同源盒基因HoxA1,A2,A3和HoxA4基因mRNA水平表达的变化。方法应用逆转录PCR(RT-PCR)及图像分析法,分组检测原代培养的大鼠星形胶质细胞及应用PA前后胶质瘤细胞C6中HoxA,A2,A3和HoxA4基因mRNA水平表达。结果HoxA1和A4基因在正常大鼠脑组织中弱表达,在胶质瘤C6细胞中存在明显表达;HoxA2基因在正常大鼠脑组织中未见表达,在胶质瘤C6细胞中存在明显表达 ...
田宇 +4 more
doaj
[Research Progress in Imaging Investigation of TERT Promoter Mutations in Gliomas]. [PDF]
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[circ_EPHB4 synergizes with YTHDF3 to promote glioma progression <i>via</i> m<sup>6</sup>A-dependent stabilization of Wnt3]. [PDF]
Jin C, Liu J, Liu B, Fei X, Liao Y.
europepmc +1 more source
Clinical features of 28 cases of anti-leucine-rich glioma-inactivated protein 1 encephalitis and anti-contactin-associated protein-like 2 encephalitis. [PDF]
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Wu Y, Lin L, Wu S.
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[Circ_EPHB4 regulates temozolomide sensitivity in glioma cells through the miR-424-5p/Wnt3 axis]. [PDF]
Liao Y, Liu J, Liu B, Fei X, Jin C.
europepmc +1 more source
[Establishment of an Engineered Bacterial Membrane Biomimetic Nanodrug Delivery System and Its Role in the Treatment of Glioma]. [PDF]
Zhao Y +9 more
europepmc +1 more source
[Establishment of a mouse model bearing orthotopic temozolomide-resistant glioma]. [PDF]
Shi L +8 more
europepmc +1 more source

