Results 1 to 10 of about 76,131 (263)
Exosomes and Atherogenesis [PDF]
Frontiers in Cardiovascular Medicine, 2021 Myocardial infarction and ischemic stroke are the leading causes of mortality worldwide. Atherosclerosis is their common pathological foundation. It is known that atherosclerosis is characterized by endothelial activation/injury, accumulation of inflammatory immune cells and lipid-rich foam cells, followed by the development of atherosclerotic plaque ...
Bingbing Lin +5 more
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Scientific Reports, 2022 Improved risk stratification of patients suspected of prostate cancer prior to biopsy continues to be an unmet clinical need. ExoDx Prostate (IntelliScore) “EPI” is a non-invasive urine test utilizing RNA from exosomes to provide a risk score that ...
Alexander Kretschmer +18 more
doaj +1 more source
Exosomes and Exosomal miRNA in Respiratory Diseases [PDF]
Mediators of Inflammation, 2016 Exosomes are nanosized vesicles released from every cell in the body including those in the respiratory tract and lungs. They are found in most body fluids and contain a number of different biomolecules including proteins, lipids, and both mRNA and noncoding RNAs.
Shamila D. Alipoor +5 more
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npj Microgravity, 2022 Molecular profiling to characterize the effects of environmental exposures is important from the human health and performance as well as the occupational medicine perspective in space exploration.
Sudipto K. Chakrabortty +11 more
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Pharmaceutics, 2022 According to clinical studies, statins improve the efficacy of programmed death-1/programmed death-ligand 1 (PD-1/PD-L1) blockade therapy for breast cancer; however, the underlying mechanisms are unclear.
Eun-Ji Choe +5 more
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Cells, 2021 Ovarian cancer (OC) is one of the most diagnosed gynecological cancers in women. Due to the lack of effective early stage screening, women are more often diagnosed at an advanced stage; therefore, it is associated with poor patient outcomes.
Priyakshi Kalita-de Croft +4 more
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A SARS-CoV-2 antigen rapid diagnostic test for resource limited settings
Scientific Reports, 2021 Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is the causative agent of COVID-19 disease. RT-qPCR has been the primary method of diagnosis; however, the required infrastructure is lacking in many developing countries and the virus has ...
Erica Frew +8 more
doaj +1 more source
EMBnet.journal, 2020 Extracellular vesicles have been the focus of a large number of studies in the past five years. Exosomes, a subgroup of extracellular vesicles, are of particularly high interest because they partake in a wide number of biological pathways. Produced by a variety of cells, exosomes have an important role in both physiological and pathological conditions.
Mitsis, Thanasis +6 more
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BMC Urology, 2020 Background Initial prostate biopsy often fails to identify prostate cancer resulting in patient anxiety, especially when clinical features such as prostate specific antigen (PSA) remain elevated, leading to the need for repeat biopsies.
James McKiernan +8 more
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The Role of Exosomes and Exosomal MicroRNA in Cardiovascular Disease [PDF]
Frontiers in Cell and Developmental Biology, 2021 Exosomes are small vesicles (30–150 nm in diameter) enclosed by a lipid membrane bilayer, secreted by most cells in the body. They carry various molecules, including proteins, lipids, mRNA, and other RNA species, such as long non-coding RNA, circular RNA, and microRNA (miRNA). miRNAs are the most numerous cargo molecules in the exosome.
Dongdong Zheng +9 more
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