Results 11 to 20 of about 76,131 (263)
Extracellular Vesicles—New Players in Cell-to-Cell Communication in Gestational Diabetes Mellitus
Biomedicines, 2022 Research in extracellular vesicles (EVs) has contributed to a better understanding of physiological and pathophysiological conditions. Biologically active cargo, such as miRNAs and proteins, is critical in many different biological processes.
Carlos Palma +2 more
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Cell, 2005 In the nucleus of eukaryotic cells, RNA decay in the 3'-5' direction is carried out by a complex of exonucleases called the exosome. Surprisingly, the purified exosome shows only weak activity in vitro. Two papers in this issue of Cell, by LaCava et al. (2005) and Wyers et al. (2005), and a third report by Vanacova et al.
Jensen, Torben Heick, Moore, Claire
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Journal of the American Society of Nephrology, 2015 Acute kidney injury, AKI, is relatively common in the hospital setting, and beyond the identification of the underlying cause and supportive measures, little can be done to facilitate healing of the compromised kidney.
Jessica, Rossol-Allison +1 more
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Extracellular vesicles from plasma have higher tumour RNA fraction than platelets
Journal of Extracellular Vesicles, 2020 In addition to Circulating Tumour Cells (CTCs), cell-free DNA (cfDNA) and Extracellular Vesicles (EVs), the notion of “Tumour-Educated Platelets” (TEP) has recently emerged as a potential source of tumour-derived biomarkers accessible through blood ...
Kay Brinkman +6 more
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Cells, 2020 Exosomes are nano-sized vesicles that serve as mediators for cell-to-cell communication. With their unique nucleic acids, proteins, and lipids cargo compositions that reflect the characteristics of producer cells, exosomes can be utilized as cell-free ...
Dae Hyun Ha +11 more
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Frontiers in Immunology, 2022 Mesenchymal stem cell small extracellular vesicles (MSC-sEVs) are a priority for researchers because of their role in tissue regeneration. sEVs act as paracrine factors and carry various cargos, revealing the state of the parent cells and contributing to
Yuting Tang +9 more
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Frontiers in Immunology, 2014 Recent studies have highlighted the importance of cross-talk between our immune systems and our gut microbiota, the complex community of over 100 trillion commensal microorganisms (bacteria, archaea, fungi, and protozoans) that resides in the human gastrointestinal tract and which numbers about 10 times the total cells in the human body (1).
Smythies, Lesley E., Smythies, John R.
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Future Science OA, 2021 Exosomes are a new horizon in modern therapy, presenting exciting new opportunities for advanced drug delivery and targeted release. Exosomes are small extracellular vesicles with a size range of 30-100 nm, secreted by all cell types in the human body and carrying a unique collection of DNA fragments, RNA species, lipids, protein biomarkers ...
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EMBO reports, 2007 The correct processing, quality control and turnover of cellular RNA molecules is crucial to many aspects of cell physiology. The exosome—a large molecular assembly with exoribonuclease activity—has emerged as a crucial component in many, if not most, stages of RNA metabolism, including degradation and maturation of ribosomal RNA, RNA quality control ...
Sophia, Hartung, Karl-Peter, Hopfner
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Hybrid exosomes, exosome-like nanovesicles and engineered exosomes for therapeutic applications
Journal of Controlled Release, 2023 Exosomes are endosome-derived nanovesicles involved in cellular communication. They are natural nanocarriers secreted by various cells, making them suitable candidates for diverse drug delivery and therapeutic applications from a material standpoint. They have a phospholipid bilayer decorated with functional molecules and an enclosed parental matrix ...
Jagannath, Mondal +6 more
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