Results 31 to 40 of about 115,399 (299)

RNA-binding protein Mub1 and the nuclear RNA exosome act to fine-tune environmental stress response

open access: yesLife Science Alliance, 2022
Comparative RNA interactome capture identifies potential regulators of RNA metabolism in fission yeast and reveals RNA exosome–dependent buffering of stress-responsive gene expression networks.
Adrien Birot   +7 more
doaj   +1 more source

EXOSC10 is required for RPA assembly and controlled DNA end resection at DNA double-strand breaks [PDF]

open access: yes, 2019
The exosome is a ribonucleolytic complex that plays important roles in RNA metabolism. Here we show that the exosome is necessary for the repair of DNA double-strand breaks (DSBs) in human cells and that RNA clearance is an essential step in homologous ...
Bonath, Franziska   +7 more
core   +2 more sources

Performance Evaluation of BD FACSPrestoTM Near-Patient CD4 Counter for Monitoring Antiretroviral Therapy in HIV-Infected Individuals in Primary Healthcare Clinics in Thailand

open access: yesDiagnostics, 2022
HIV viral load is more reliable tool for monitoring treatment throughout the course of HIV/AIDS, but the test may be expensive in resource-limited settings. Therefore, enumeration of CD4 T-lymphocyte count remains important in these settings.
Kasama Sukapirom   +5 more
doaj   +1 more source

Nanopillar and nanohole fabrication via mixed lithography

open access: yesMaterials Research Express, 2020
We report a fabrication method for the production of nanopillar (NP) or nanohole (NH) arrays together with a micrometer-sized structure within a single layer.
Seung Hee Baek   +7 more
doaj   +1 more source

The link between gestational diabetes and cardiovascular diseases: potential role of extracellular vesicles

open access: yesCardiovascular Diabetology, 2022
Extracellular vesicles are critical mediators of cell communication. They encapsulate a variety of molecular cargo such as proteins, lipids, and nucleic acids including miRNAs, lncRNAs, circular RNAs, and mRNAs, and through transfer of these molecular ...
Valeska Ormazabal   +4 more
doaj   +1 more source

The Effects of Exosomes on the Regeneration of Rat Calvaria [PDF]

open access: yes, 2020
Periodontal disease is a bacterial induced chronic inflammatory condition that occurs in a susceptible host, affecting the teeth, gingiva, periodontal ligament, and alveolar bone.
Beitz, Jill T
core   +1 more source

An optimized exosome production strategy for enhanced yield while without sacrificing cargo loading efficiency

open access: yesJournal of Nanobiotechnology, 2022
Background Exosome mediated mRNA delivery is a promising strategy for the treatment of multiple diseases. However, the low yield of exosomes is a bottleneck for clinical translation.
Rongxin Zhang   +8 more
doaj   +1 more source

Cryo-self-assembled silk fibroin sponge as a biodegradable platform for enzyme-responsive delivery of exosomes

open access: yesBioactive Materials, 2022
Although advances in protein assembly preparation have provided a new platform for drug delivery during tissue engineering, achieving long-term controlled exosome delivery remains a significant challenge. Diffusion-dominated exosome release using protein
Muyang Sun   +11 more
doaj   +1 more source

Exosomes containing HIV protein Nef reorganize lipid rafts potentiating inflammatory response in bystander cells. [PDF]

open access: yes, 2019
HIV infection has a profound effect on "bystander" cells causing metabolic co-morbidities. This may be mediated by exosomes secreted by HIV-infected cells and containing viral factors.
Brichacek, Beda   +15 more
core   +3 more sources

A new landscape of host–protozoa interactions involving the extracellular vesicles world [PDF]

open access: yes, 2018
This version is free to view and download for private research and study only. Not for re-distribution, re-sale or use in derivative works. © Cambridge University Press 2018Extracellular vesicles (EVs) are released by a wide number of cells including ...
Bruno Gavinho   +11 more
core   +2 more sources

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