Results 31 to 40 of about 76,131 (263)

Exosome and Exosomal MicroRNA: Trafficking, Sorting, and Function

open access: yesGenomics, Proteomics & Bioinformatics, 2015
Abstract Exosomes are 40–100 nm nano-sized vesicles that are released from many cell types into the extracellular space. Such vesicles are widely distributed in various body fluids. Recently, mRNAs and microRNAs (miRNAs) have been identified in exosomes, which can be taken up by neighboring or distant cells and subsequently modulate ...
Jian Zhang 0017   +6 more
openaire   +3 more sources

Quantification of Exosomes [PDF]

open access: yesJournal of Cellular Physiology, 2017
Exosomes are released by cells as self‐contained vesicles with an intact lipid bilayer that encapsulates a small portion of the parent cell. Exosomes have been studied widely as information‐rich sources of potential biomarkers that can reveal cellular physiology.
Erik H, Koritzinsky   +3 more
openaire   +2 more sources

The role of the Arabidopsis Exosome in siRNA-independent silencing of heterochromatic loci. [PDF]

open access: yesPLoS Genetics, 2013
The exosome functions throughout eukaryotic RNA metabolism and has a prominent role in gene silencing in yeast. In Arabidopsis, exosome regulates expression of a "hidden" transcriptome layer from centromeric, pericentromeric, and other heterochromatic ...
Jun-Hye Shin   +5 more
doaj   +1 more source

Ascorbate peroxidase‐mediated in situ labelling of proteins in secreted exosomes

open access: yesJournal of Extracellular Vesicles, 2022
The extracellular vesicle exosome mediates intercellular communication by transporting macromolecules such as proteins and ribonucleic acids (RNAs). Determining cargo contents with high accuracy will help decipher the biological processes that exosomes ...
Byung Rho Lee   +7 more
doaj   +1 more source

RNA-binding protein Mub1 and the nuclear RNA exosome act to fine-tune environmental stress response

open access: yesLife Science Alliance, 2022
Comparative RNA interactome capture identifies potential regulators of RNA metabolism in fission yeast and reveals RNA exosome–dependent buffering of stress-responsive gene expression networks.
Adrien Birot   +7 more
doaj   +1 more source

Role of Exosomes and Exosomal microRNAs in Cancer

open access: yesFuture Science OA, 2020
A growing body of evidence indicates that exosomes play a critical role in the cell-cell communication process. Exosomes are biological nanoparticles with an average diameter of 30-100 nm in size and are produced by almost all cell types in the human body; however, cancer cells contain higher concentrations of exosomes than healthy cells.
openaire   +3 more sources

Cryo-self-assembled silk fibroin sponge as a biodegradable platform for enzyme-responsive delivery of exosomes

open access: yesBioactive Materials, 2022
Although advances in protein assembly preparation have provided a new platform for drug delivery during tissue engineering, achieving long-term controlled exosome delivery remains a significant challenge. Diffusion-dominated exosome release using protein
Muyang Sun   +11 more
doaj   +1 more source

No ESCRTs for Exosomes

open access: yesScience, 2008
Two pathways within endosomes use specific protein complexes or membrane domains to direct cargo for degradation or secretion from cells.
Marsh, M., van Meer, G.
openaire   +3 more sources

Nanopillar and nanohole fabrication via mixed lithography

open access: yesMaterials Research Express, 2020
We report a fabrication method for the production of nanopillar (NP) or nanohole (NH) arrays together with a micrometer-sized structure within a single layer.
Seung Hee Baek   +7 more
doaj   +1 more source

Finding the Exosome [PDF]

open access: yes, 2010
We describe the events surrounding the identification of the exosome complex and the subsequent early development of the field. Like many scientific discoveries, the initial identification and characterization ofthe exosome was based on a combination of skill, good fortune--and the availability of cutting edge technology.
Mitchell, Phil, Tollervey, David
openaire   +4 more sources

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