Results 31 to 40 of about 88,162 (311)

Exosomes

open access: yesAnnual Review of Biochemistry, 2019
Exosomes are small, single-membrane, secreted organelles of ∼30 to ∼200 nm in diameter that have the same topology as the cell and are enriched in selected proteins, lipids, nucleic acids, and glycoconjugates. Exosomes contain an array of membrane-associated, high-order oligomeric protein complexes, display pronounced molecular heterogeneity, and are ...
Pegtel, D. Michiel, Gould, Stephen J.
openaire   +2 more sources

Exosome Mimetics-Loaded Hydrogel Accelerates Wound Repair by Transferring Functional Mitochondrial Proteins

open access: yesFrontiers in Bioengineering and Biotechnology, 2022
Loading human umbilical mesenchymal stem cell (hUMSC) derived exosomes onto hydrogel scaffolds is a strategy for rapid wound healing. The clinical application of exosomes is hindered by low production, and exosome mimetics could be substituted for ...
Jie Zhu   +12 more
doaj   +1 more source

Exosomes derived from human adipose tissue-derived mesenchymal stem cells alleviate atopic dermatitis

open access: yesStem Cell Research & Therapy, 2018
Exosomes are nano-sized vesicles (30–200 nm) constantly released by almost all cells. The ability of exosomes to travel between cells and deliver their cargo, which includes lipids, proteins, and nucleic acids, makes them an appealing cell-free therapy ...
Byong Seung Cho   +3 more
doaj   +1 more source

Recent advances of emerging microfluidic chips for exosome mediated cancer diagnosis

open access: yesSmart Materials in Medicine, 2021
Recent technological advances in the field of microfluidic chips have provided great opportunities to boost the development of exosome-based cancer diagnosis.
Le Wang   +4 more
doaj   +1 more source

Exosomes in cancer

open access: yes, 2021
Exosomes are small extracellular vesicles released by cells under physiological and pathological conditions. There is emerging evidence associating exosomes with tumorigenesis. They carry cargo (DNA, RNA, miRNA and protein) pertaining to the cell of origin and play a key role in intercellular communication, influencing several cellular processes ...
Müller Bark, Juliana   +3 more
openaire   +4 more sources

The mRNA encoding the yeast ARE-binding protein Cth2 is generated by a novel 3 ' processing pathway [PDF]

open access: yes, 2008
Microarray analyses of mRNAs over-expressed in strains lacking the nuclear exosome component Rrp6 identified the transcript encoding the ARE-binding protein Cth2, which functions in cytoplasmic mRNA stability.
Bohnsack, Markus T.   +2 more
core   +1 more source

Modeling exosome complexes from cross-link MS data [PDF]

open access: yes, 2015
<p>This repository contains the modeling scripts, the ensemble of models, and the results of the analysis for the modeling of the <em>S.cerevisiae</em> exosome complex (named exo10, comprising of Rrp40, Rrp4, Csl4, Rrp45, Rrp46, Rrp42 ...
Shi, Yi   +19 more
core   +3 more sources

Human urinary exosomes in bladder cancer patients : properties, concentrations and possible clinical application [PDF]

open access: yes, 2015
OBJECTIVE: High grade bladder cancer is extremely aggressive. Early detection is thus an important challenge. De- velopment of non-invasive diagnostic tools particularly using urine samples could be of importance in the diagnosis and surveillance of ...
Mullen, Peter   +11 more
core   +1 more source

Skin Brightening Efficacy of Exosomes Derived from Human Adipose Tissue-Derived Stem/Stromal Cells: A Prospective, Split-Face, Randomized Placebo-Controlled Study

open access: yesCosmetics, 2020
Studies have shown that stem cells and their derivatives, including conditioned media (CM), have inhibitory effects on skin pigmentation. However, evidence supporting the skin brightening effect of exosomes derived from stem cells is lacking.
Byong Seung Cho   +14 more
doaj   +1 more source

Exosomes are natural carriers of exogenous siRNA to human cells in vitro [PDF]

open access: yes, 2013
© 2013 Shtam et al. Background: Exosomes are nano-sized vesicles of endocytic origin that are involved in cell-to-cell communication including shuttle RNA, mainly mRNA and microRNA.
Varfolomeeva, EY   +5 more
core   +1 more source

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