Results 51 to 60 of about 94,365 (207)

Nanopillar and nanohole fabrication via mixed lithography

open access: yesMaterials Research Express, 2020
We report a fabrication method for the production of nanopillar (NP) or nanohole (NH) arrays together with a micrometer-sized structure within a single layer.
Seung Hee Baek   +7 more
doaj   +1 more source

RNA-binding protein Mub1 and the nuclear RNA exosome act to fine-tune environmental stress response

open access: yesLife Science Alliance, 2022
Comparative RNA interactome capture identifies potential regulators of RNA metabolism in fission yeast and reveals RNA exosome–dependent buffering of stress-responsive gene expression networks.
Adrien Birot   +7 more
doaj   +1 more source

Distinct roles of non-canonical poly(A) polymerases in RNA metabolism [PDF]

open access: yes, 2009
Trf4p and Trf5p are non-canonical poly(A) polymerases and are part of the heteromeric protein complexes TRAMP4 and TRAMP5 that promote the degradation of aberrant and short-lived RNA substrates by interacting with the nuclear exosome. To assess the level
Schenk, L.   +27 more
core   +1 more source

Separation of distinct exosome subpopulations: isolation and characterization approaches and their associated challenges

open access: yes, 2021
Exosomes are nano-sized extracellular vesicles that serve as a communications system between cells and have shown tremendous promise as liquid biopsy biomarkers in diagnostic, prognostic, and even therapeutic use in different human diseases.
Bose, Sudeep   +5 more
core   +1 more source

The link between gestational diabetes and cardiovascular diseases: potential role of extracellular vesicles

open access: yesCardiovascular Diabetology, 2022
Extracellular vesicles are critical mediators of cell communication. They encapsulate a variety of molecular cargo such as proteins, lipids, and nucleic acids including miRNAs, lncRNAs, circular RNAs, and mRNAs, and through transfer of these molecular ...
Valeska Ormazabal   +4 more
doaj   +1 more source

Differential expression of exosomal microRNAs in prefrontal cortices of schizophrenia and bipolar disorder patients [PDF]

open access: yes, 2013
Exosomes are cellular secretory vesicles containing microRNAs (miRNAs). Once secreted, exosomes are able to attach to recipient cells and release miRNAs potentially modulating the function of the recipient cell.
Andrea Schmitt   +49 more
core   +1 more source

Cryo-self-assembled silk fibroin sponge as a biodegradable platform for enzyme-responsive delivery of exosomes

open access: yesBioactive Materials, 2022
Although advances in protein assembly preparation have provided a new platform for drug delivery during tissue engineering, achieving long-term controlled exosome delivery remains a significant challenge. Diffusion-dominated exosome release using protein
Muyang Sun   +11 more
doaj   +1 more source

An optimized exosome production strategy for enhanced yield while without sacrificing cargo loading efficiency

open access: yesJournal of Nanobiotechnology, 2022
Background Exosome mediated mRNA delivery is a promising strategy for the treatment of multiple diseases. However, the low yield of exosomes is a bottleneck for clinical translation.
Rongxin Zhang   +8 more
doaj   +1 more source

Exosomes and exosomal miRNAs in cardiovascular protection and repair [PDF]

open access: yesVascular Pharmacology, 2015
Cell-cell communication between cardiac and vascular cells and from stem and progenitor cells to differentiated cardiovascular cells is both an important and complex process, achieved through a diversity of mechanisms that have an impact on cardiovascular biology, disease and therapeutics.
Emanueli, Costanza   +3 more
openaire   +3 more sources

Exosome-delivered circRNA circSYT15 contributes to cisplatin resistance in cervical cancer cells through the miR-503-5p/RSF1 axis

open access: yes, 2023
The development of chemotherapy resistance is a major obstacle for cervical cancer (CC) patients. Exosome-mediated transfer of circular RNAs (circRNAs) was found to have relevance to the CC.
Zhen Xu (92379)   +8 more
core   +1 more source

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