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Intracellular coassembly boosts the anti-inflammation capacity of dexamethasone [PDF]

open access: yesNanoscale, 2017
An intracellular coassembly strategy was developed to boost the anti-inflammation capacity of dexamethasone.
Wei Tang   +4 more
openaire   +3 more sources
Some of the next articles are maybe not open access.

Rutin-Loaded Stimuli-Responsive Hydrogel for Anti-Inflammation

ACS Applied Materials & Interfaces, 2022
An active flavonoid compound rutin was incorporated into a guanosine phenylborate hydrogel (GBR) by a stimuli-responsive borate ester linkage for the treatment of inflammatory bowel disease (IBD). The components and morphology of the drug delivery system were characterized by NMR, UV-vis spectroscopy, and AFM.
Hongyue Wang   +6 more
openaire   +2 more sources

Neutrophil‐targeted engineered prodrug nanoparticles for anti‐inflammation

The FASEB Journal, 2020
Abstract Inflammation response is a defense to infection induced by invading pathogen or tissue injury. However, exaggerated inflammation may cause autoimmune or inflammatory disorders, such as acute respiratory distress syndrome, sepsis, stroke and rheumatoid arthritis.
Jinping, Shi, Juan, Li
openaire   +2 more sources

ART for Anti-inflammation

2015
Chronic/acute synovitis, an early phase of RA, can be experimentally induced in mice by autoantigen/bacterial antigen challenging and live bacterial feeding. While a donor of NO replicates the modeling of synovitis, an inhibitor of NOS blocks the progression of synovitis, suggesting inflammation-triggered NO burst represents an etiological cause of ...
openaire   +1 more source

Effect of food on kinetics of the nonsteroidal anti‐inflammative, alclofenac

Clinical Pharmacology & Therapeutics, 1978
Two clinical studies were conducted on the kinetics of alclofenac in healthy adult male volunteers. The first involved 32 subjects, each of whom received a single oral 500‐mg dose of alclofenac as an aqueous suspension to study the oral pharmacokinetics of the drug.
L T, Sennello, R C, Sonders, N, Friedman
openaire   +2 more sources

Anti-inflammation and Antifibroblastic Actions of Interleukin-1 Blockers

Journal of Ocular Pharmacology and Therapeutics, 1998
Interleukin-1 (IL-1) blockers, CK 127 and CK 129, were found to inhibit IL-1-induced posterior uveitis very effectively at 3-10 mg/kg i.p. and were more potent than prednisolone which required at least 20 mg/kg i.p. to achieve the same level of anti-uveitis action.
G C, Chiou   +3 more
openaire   +2 more sources

Anti-inflammation furanoditerpenoids from Caesalpinia minax Hance

Phytochemistry, 2015
Cassane skeletons are rare in nature, but often possess valuable medicinal properties. A furanoditerpenoid with an unusual A-seco-rearranged cassane skeleton, neocaesalminin A, and five furanoditerpenoids were isolated from seeds of Caesalpinia minax Hance, along with six known cassane derivatives, 7-O-acetyl-bonducellpin C, caesalmin F, caesalmin C, ζ-
Dong, Ruijuan   +6 more
openaire   +2 more sources

Estrogen Neuroprotection and Anti-Inflammation Actions in the Hippocampus

2020
Abstract The steroid hormone 17β-estradiol (E2) is neuroprotective in several neurodegenerative conditions, including cerebral ischemia, traumatic brain injury, and Alzheimer’s disease (AD). This chapter focuses on the evidence supporting a neuroprotective role of E2 in the hippocampus in cerebral ischemia and AD and reviews various ...
Roshni D. Thakkar   +4 more
openaire   +1 more source

The anti-inflammation pharmacodynamics of lithium: Therapy of bipolar disorder

Journal of Psychopharmacology
Bipolar disorder is a severe mental disorder that necessitates effective long-term treatment strategies. Clinically, lithium has demonstrated favorable outcomes in managing this condition. The inflammatory theory posits that bipolar disorder is influenced by an inflammatory response, and lithium is thought to mitigate this disorder by inhibiting such ...
Yuyang Zhou   +4 more
openaire   +2 more sources

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