Results 21 to 30 of about 3,781,173 (304)

Inflammation‐Controlled Anti‐Inflammatory Hydrogels

Advanced Science, 2023
While autoregulative adaptation is a common feature of living tissues, only a few feedback‐controlled adaptive biomaterials are available so far. This paper herein reports a new polymer hydrogel platform designed to release anti‐inflammatory molecules in
Tina Helmecke, Dominik Hahn, Nadine Matzke, Lisa Ferdinand, Lars Franke, Sebastian Kühn, Gunter Fischer, Carsten Werner, Manfred F. Maitz   +8 more
doaj   +1 more source

Protein acetylation and related potential therapeutic strategies in kidney disease

Pharmacological Research, 2023
Kidney disease can be caused by various internal and external factors that have led to a continual increase in global deaths. Current treatment methods can alleviate but do not markedly prevent disease development.
Xiang-yu Li, Ju-tao Yu, Yu-hang Dong, Xiao-yu Shen, Rui Hou, Man-man Xie, Jie Wei, Xiao-wei Hu, Ze-hui Dong, Run-run Shan, Juan Jin, Wei Shao, Xiao-ming Meng   +12 more
doaj   +1 more source

Circular RNA circPSD3 alleviates hepatic fibrogenesis by regulating the miR-92b-3p/Smad7 axis

Molecular Therapy: Nucleic Acids, 2021
Recently, circular RNAs (circRNAs) have been frequently reported to be involved in hepatocellular carcinoma (HCC) development and progression. However, the role of circRNAs in hepatic fibrosis (HF) is still unclear.
Fang-tian Bu, Yan Zhu, Xin Chen, Ao Wang, Ya-fei Zhang, Hong-mei You, Yang Yang, Ya-ru Yang, Cheng Huang, Jun Li   +9 more
doaj   +1 more source

Anti-hyperalgesic and anti-inflammatory activity of Alternanthera maritima extract and 2″-O-α-L-rhamnopyranosylvitexin in mice

, 2015
Alternanthera maritima are used in Brazilian popular medicine for the treatment of inflammatory and infectious diseases. Species of Alternanthera have demonstrated biological activities in previous scientific studies.
Arena, Arielle Cristina [UNESP], Aquino, Diana Figuereido de Santana, Salvador, Marcos José, Kassuya, Candida Aparecida Leite, Piccinelli, Ana Claudia, Arena, Arielle Cristina, Soares, Fabíola Lacerda Pires   +6 more
core   +1 more source

Inhibiting corneal neovascularization by sustainably releasing anti-VEGF and anti-inflammation drugs from silica-thermogel nanohybrids

, 2021
Corneal neovascularization (CNV) is one of the main factors that induce blindness worldwide. To effectively inhibit CNV, a novel nanohybrid has been developed by incorporating anti-VEGF bevacizumab (BEV)-loaded mesoporous silica nanoparticles (BEV@MSN ...
Ning Lyu, Chang Huang, Xu, ZP, Xinghuai Sun, Fan, X, Jun Xiang, Sun, J, Xiangyu Fan, Huang, C, Xiang, J, Xu, J, Yujin Zhao, Zhi Ping Xu, Zhao, Y, Lyu, N, Sun, X, Jianguo Sun, Jianjiang Xu   +17 more
core   +1 more source

Effects of Amentoflavone on Anti-inflammation and Cytoprotection [PDF]

Asian Journal of Beauty and Cosmetology, 2016
목적: 본 연구의 목적은 amentoflavone의 항염증 및 세포 보호 효과를 확인하여 화장품, 의약품 원료로서의 가능성을 검증하는데 있다 . 방법: Amentoflavone의 항염증 효과를 확인하기 위하여, qRT-PCR를 이용하여 TNF-α, IL-6와 같은in flammatory cytokine의 발현량을 측정하였다. 그리고 NF-κB의 발현량을 확인하기 위해 NF-κB rpomoter luciferase assay를 수행하였다.
Songjeong Lee, Hyo Sun Han, In-Sook An, Kyu Joong Ahn   +3 more
openaire   +1 more source

The role of lncRNA in the pathogenesis of chronic obstructive pulmonary disease

Heliyon, 2023
Chronic obstructive pulmonary disease (COPD) is characterized by progressive and irreversible airflow obstruction with abnormal lung function. Because its pathogenesis involves multiple aspects of oxidative stress, immunity and inflammation, apoptosis ...
Jing Xie, Yongkang Wu, Qing Tao, Hua Liu, Jingjing Wang, Chunwei Zhang, Yuanzhi Zhou, Chengyan Wei, Yan Chang, Yong Jin, Zhen Ding   +10 more
doaj   +1 more source

Antioxidant and anti-inflammatory function of Eupatorium adenophora Spreng leaves (EASL) on human intestinal Caco-2 cells treated with tert-butyl hydroperoxide

Scientific Reports
Chronic non-communicable diseases (CNCDs) pose a significant public health challenge. Addressing this issue, there has been a notable breakthrough in the prevention and mitigation of NCDs through the use of antioxidants and anti-inflammatory agents.
Li Zheng-qiang, Ni Jun, Zhu Xin-yu, Zhang Chao-zhi, An Rui, Yang Xu, She Rong, Yang Xiao-yan   +7 more
doaj   +1 more source

Pediatric Idiopathic Multicentric Castleman Disease Is Often Severe But Responsive to Siltuximab

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Idiopathic multicentric Castleman disease (iMCD) is a potentially fatal immunologic disorder marked by widespread lymphadenopathy and inflammation. Siltuximab, an interleukin‐6 (IL‐6) inhibitor, is the only FDA‐approved treatment for adult patients with iMCD.
Bridget Austin, Sheila K. Pierson, Kelley C. Dacus, Mateo Sarmiento Bustamante, Saishravan Shyamsundar, Larissa Borys, Kayla McHugh, Abiola Irvine, Yoojin Jo, Adam Bagg, Mary Jo Lechowicz, Daisy Alapat, Amy Chadburn, Megan S. Lim, Gordan Srkalovic, Frits van Rhee, David C. Fajgenbaum, Joshua D. Brandstadter   +17 more
wiley   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source