[<i>Jiangzhi Quban</i> Recipe improves type 2 diabetes mellitus complicated with hyperlipidemia by multi-target regulation of the inflammation-metabolism network: network pharmacology analysis and clinical validation]. [PDF]
Nan Fang Yi Ke Da Xue Xue BaoLi Z +6 more
europepmc +1 more source
基于MALDI-TOF-MS的脂质组学研究——鲫鱼受镉暴露的潜在生物标志物
以含镉（Cd）500μg/L水体中养殖0,10,20 d的3组鲫鱼为研究对象,测定鱼肉中Cd含量,借助HPLC与MALDI-TOF-MS离线联用技术得到鱼肉磷脂图谱,并采用偏最小二乘判别分析法（PLS-DA）针对图谱数据开展模式识别分析.结果表明,在20 d暴露期内,鱼肉中Cd含量呈持续上升趋势,而磷脂酰胆碱（PC）含量在暴露10 d后显著低于正常水平（未受镉暴露）（p〈0.05）,暴露20 d后基本恢复到正常水平.PLS-DA分析实现了3组样本的组间判别 ...
吴仁安 +3 more
core +1 more source
[Formononetin downregulates P53/SAT1/ACSL4 pathway-mediated ferroptosis to improve hypoxic-ischemic brain injury in neonatal mice]. [PDF]
Nan Fang Yi Ke Da Xue Xue BaoGuo T +8 more
europepmc +1 more source
Zhongguo shiyan zhenduanxue目的 探讨老年糖尿病患者内脏脂肪面积、骨密度和骨代谢指标水平及意义。方法 选取2021年6月至2022年8月在四川大学华西医院就诊的老年糖尿病患者160例作为观察组，选取同期健康体检老年人160例作为对照组，检查两组内脏脂肪面积、骨密度、Ⅰ型胶原羧基端肽β特殊序列（β-CTX）、总Ⅰ型前胶原氨基端延长肽（TPⅠNP）和骨钙素（OC）水平。分析老年糖尿病患者内脏脂肪面积、骨密度和骨代谢指标水平与患者临床特征的关系，及内脏脂肪面积与骨密度、骨代谢指标间相关性。结果 观察组内脏脂肪面积、β ...
胡婕, 练夏夷, 白莉, 王静
doaj
[Characterization of liver macrophage subsets in different mouse models of metabolic associated steatohepatitis]. [PDF]
Zhonghua Gan Zang Bing Za ZhiXia EZ +8 more
europepmc +1 more source
[Total and regional fat-to-muscle mass ratio and risk of incident benign ovarian neoplasm]. [PDF]
Beijing Da Xue Xue Bao Yi Xue BanLi H, Huang T, Wang L.
europepmc +1 more source
野生动物学报褐色脂肪组织（brown adipose tissue，BAT）是哺乳动物重要的适应性产热器官。BAT内有丰富的线粒体和多种脂质成分。线粒体形态的维持，包括融合与分裂，与产热效率密切相关，影响细胞能量代谢，而脂质代谢在提供产热底物中扮演核心角色。BAT产热能力在冬眠哺乳动物的深冬眠和阵间觉醒期间存在快速且显著的周期性变化，然而其中的调节机制尚不明确。本综述从线粒体动力学和脂质成分变化的角度综合了当前对BAT产热机制的理解，探讨了哺乳类冬眠动物BAT线粒体形态和脂质成分在冬眠和非冬眠状态下的变化 ...
陈欣钰, 付有涛, 杨明, 邢昕
doaj
[EVA1A overexpression improves non-alcoholic fatty liver disease in mice by regulating lipid metabolism and promoting lipophagy]. [PDF]
Nan Fang Yi Ke Da Xue Xue BaoXu J +8 more
europepmc +1 more source
[Recent Advances in the Interorgan Regulatory Roles of Adipose Tissue]. [PDF]
Sichuan Da Xue Xue Bao Yi Xue BanLi Z, Xu C, Xu R, Zhou C, Fan Y.
europepmc +1 more source
[Analysis of potential association of alcohol exposure with femoral head osteonecrosis and construction of a diagnostic model using machine learning]. [PDF]
Nan Fang Yi Ke Da Xue Xue BaoTao H, Liang F, Huang W, Fan S, Zeng P.
europepmc +1 more source