基于MALDI-TOF-MS的脂质组学研究——鲫鱼受镉暴露的潜在生物标志物
以含镉(Cd)500μg/L水体中养殖0,10,20 d的3组鲫鱼为研究对象,测定鱼肉中Cd含量,借助HPLC与MALDI-TOF-MS离线联用技术得到鱼肉磷脂图谱,并采用偏最小二乘判别分析法(PLS-DA)针对图谱数据开展模式识别分析.结果表明,在20 d暴露期内,鱼肉中Cd含量呈持续上升趋势,而磷脂酰胆碱(PC)含量在暴露10 d后显著低于正常水平(未受镉暴露)(p〈0.05),暴露20 d后基本恢复到正常水平.PLS-DA分析实现了3组样本的组间判别 ...
吴仁安 +3 more
core +1 more source
[Long-term prognosis and influencing factors of anterior composite resin restoration]. [PDF]
Chen W, Wu F, Wei X.
europepmc +1 more source
[Research Progress on the Role and Regulatory Mechanisms of Lipid Metabolism in the Osteogenic/Odontogenic Differentiation of Dental Stem Cells]. [PDF]
An K, Xie J, Zhou X.
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[Extracellular matrix materials and tissue regeneration and repair]. [PDF]
Zhao L, Xie H.
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肥胖儿童血清omentin-1和vaspin水平及其与脂代谢的关系
【目的】 探讨肥胖儿童血清omentin-1?vaspin水平及其与脂代谢的关系?【方法】 59名儿童参加本研究,肥胖组30人,年龄(9.43 ± 2.02)岁,对照组29人,年龄(10.3 ± 2.2)岁,两组年龄无显著差异(P > 0.05)?采用ELISA法检测血清omentin-1和vaspin水平?采用生化检测测定空腹血脂和空腹血糖?采用化学发光法检测空腹胰岛素?计算每个个体的体质量指数(BMI)?体质量指数Z积分(BMI-SDS)及胰岛素抵抗指数(HOMA-IR)?【结果】 肥胖组的BMI ...
doaj
[Shihu Mixture alleviates diabetic cardiomyopathy in rats by Sirt3-mediated upregulation of myocardial mitochondrial mitophagy pathway]. [PDF]
Lin X, He Y, Shi H, Liu J, Hu H.
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[Exposures to volatile organic compounds are positively correlated with risks of metabolic dysfunction-associated steatotic liver disease]. [PDF]
Li K, Zeng W, Zhang Y, Zhu X, Guo B.
europepmc +1 more source
[Research progress on biomarkers for endometriosis based on lipidomics]. [PDF]
Lin C, Chen Z, Wang C, Xi Y.
europepmc +1 more source
[Research progress on extracellular vesicles derived from platelet-rich plasma in tissue repair and regeneration]. [PDF]
Han J, Cheng B.
europepmc +1 more source
[Metabolomic alterations in preterm infants with bronchopulmonary dysplasia]. [PDF]
Wu YY +10 more
europepmc +1 more source

