Results 41 to 50 of about 466 (91)

Nurr1基因修饰人脐血间充质干细胞源性多巴胺能 神经元移植治疗帕金森病

Zhongshan Daxue xuebao. Yixue kexue ban, 2009
【目的】 探讨Nurr1基因修饰的人脐血间充质干细胞(HUCB-MSC)源性的多巴胺能神经元移植对帕金森病(PD)模型鼠的治疗作用.【方法】 SD大鼠PD模型随机分为假手术组(A组)?单纯HUCB-MSC组(B组)、Nurr1基因修饰HUCB-MSC组(C组)。将HUCB-MSC及Nurr1基因修饰后的HUCB-MSC体外分化为多巴胺能神经元,并通过立体定向的手段将其移植入毁损侧纹状体,观察移植前后PD模型大鼠旋转行为的变化和脑内多巴胺(DA)含量的改变,以及纹状体区酪氨酸羟化酶 (TH) 表达的变化。【
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[Human umbilical cord mesenchymal stem cells protect against neonatal white matter injury by activating the Nrf2/Keap1/HO-1 signaling pathway]. [PDF]

Zhongguo Dang Dai Er Ke Za Zhi
Wang C, Wang MX, Zhu YP.
europepmc   +1 more source

[Chitosan hydrogel loaded with human umbilical cord mesenchymal stem cell-derived exosomes promotes healing of chronic diabetic wounds in rats]. [PDF]

Nan Fang Yi Ke Da Xue Xue Bao
Qiu X, Wang M, Tang J, Zhou J, Jin C.
europepmc   +1 more source

[Human umbilical cord mesenchymal stem cell grafting alleviates inflammatory response in type 1 diabetic mice by suppressing M1 macrophage polarization through Chi3l1]. [PDF]

Nan Fang Yi Ke Da Xue Xue Bao
Liu X, Xu Y, Sheng H, Liu H.
europepmc   +1 more source

[Application of umbilical cord mesenchymal stem cells in the treatment of severe immune-mediated thrombocytopenia after allogeneic hematopoietic stem cell transplantation in children]. [PDF]

Zhongguo Dang Dai Er Ke Za Zhi
Zhang B, Luan Z, Tang XF, Wu NH.
europepmc   +1 more source

[Role of the nuclear factor-kappa B signaling pathway in the repair of white matter injury in neonatal rats through human umbilical cord mesenchymal stem cell transplantation]. [PDF]

Zhongguo Dang Dai Er Ke Za Zhi
Zhang SJ, Wang C, Xu QQ, Zhang J, Zhu YP.   +4 more
europepmc   +1 more source

[Immunomodulatory mechanism of umbilical cord mesenchymal stem cells modified by miR-125b-5p in systemic lupus erythematosus]. [PDF]

Beijing Da Xue Xue Bao Yi Xue Ban
Wu Z, Hu M, Zhao Q, Lv F, Zhang J, Zhang W, Wang Y, Sun X, Wang H.   +8 more
europepmc   +1 more source

[Repair effect of different doses of human umbilical cord mesenchymal stem cells on white matter injury in neonatal rats]. [PDF]

Zhongguo Dang Dai Er Ke Za Zhi
Zhang J, Li MX, Wang C, Xu QQ, Zhang SJ, Zhu YP.   +5 more
europepmc   +1 more source

[Successful treatment of a hepatitis B-related acute-on-chronic liver failure patient with adefovir dipivoxil combined with artificial liver and human umbilical mesenchymal stem cells]. [PDF]

Zhonghua Gan Zang Bing Za Zhi
Niu JJ, Wang F, Xin YN, Chen LZ.
europepmc   +1 more source

Human umbilical cord mesenchymal stem cells attenuate diabetic nephropathy through the IGF1R-CHK2-p53 signalling axis in male rats with type 2 diabetes mellitus. [PDF]

J Zhejiang Univ Sci B
Zhang H, Wang X, Hu B, Li P, Abuduaini Y, Zhao H, Jieensihan A, Chen X, Wang S, Guo N, Yuan J, Li Y, Li L, Yang Y, Liu Z, Tang Z, Wang H.   +16 more
europepmc   +1 more source