Results 1 to 10 of about 245,684 (269)

Decoding transcription and microRNA-mediated translation control in Drosophila development [PDF]

open access: yes, 2010
The spatio-temporal regulation of gene expression lies at the heart of animal development. In this article we present an overview of our recent work to apply systems biological approaches to the study of transcription and microRNA-mediated translation ...
Gaul, Ulrike
core   +1 more source

CHO microRNA engineering is growing up : recent successes and future challenges [PDF]

open access: yes, 2013
microRNAs with their ability to regulate complex pathways that control cellular behavior and phenotype have been proposed as potential targets for cell engineering in the context of optimization of biopharmaceutical production cell lines, specifically of
Grillari, Johannes   +12 more
core   +1 more source

Evaluation of Stem-Loop Reverse Transcription and Poly-A Tail Extension in MicroRNA Analysis of Body Fluids [PDF]

open access: yes, 2014
MicroRNA has been demonstrated to be a viable tool for body fluid identification purposes in forensic casework. Stem-loop reverse transcription (slRT) is regularly used for cDNA synthesis from mature miRNA, along with poly-A tail extension.
Williams, Graham A.   +3 more
core   +1 more source

Functional microRNA high throughput screening reveals miR-9 as a central regulator of liver oncogenesis by affecting the PPARA-CDH1 pathway [PDF]

open access: yes, 2015
Background: Hepatocellular carcinoma (HCC) is the second leading cause of cancer-related deaths, reflecting the aggressiveness of this type of cancer and the absence of effective therapeutic regimens.
Drakaki, A   +23 more
core   +1 more source

Characterisation of body fluid specific microRNA markers by capillary electrophoresis [PDF]

open access: yes, 2013
The characterisation of RNA molecules for the purpose of body fluid identification is currently a major field in forensic genetics; with a great deal of effort going towards the analysis of messenger RNA (mRNA).
World, Damien   +6 more
core   +1 more source

Body fluid mixtures; resolution using forensic microRNA analysis [PDF]

open access: yes, 2013
Body fluid identification is a crucial aspect of forensic biology; particularly in sexual assaults which is usually characterised as a mixture of body fluids.
World, Damien   +5 more
core   +1 more source

Mechanisms of microRNA mediated gene silencing in C. elegans [PDF]

open access: yes, 2009
Mechanisms of microRNA mediated gene silencing in C. elegans Xavier Ding Dissertation abstract microRNAs (miRNAs) are a large family of small non-coding RNAs, which post-transcriptionally repress numerous genes; a type of regulation which is ...
Ding, Xavier
core   +1 more source

MMpred: functional miRNA – mRNA interaction analyses by miRNA expression prediction [PDF]

open access: yes, 2012
Background: MicroRNA (miRNA) directed gene repression is an important mechanism of posttranscriptional regulation. Comprehensive analyses of how microRNA influence biological processes requires paired miRNA-mRNA expression datasets.
Wilson, Paul   +5 more
core   +1 more source

miREE: miRNA Recognition Elements Ensemble [PDF]

open access: yes, 2011
Background Computational methods for microRNA target prediction are a fundamental step to understand the miRNA role in gene regulation, a key process in molecular biology. In this paper we present miREE, a novel microRNA target prediction tool.
Enrico Macii   +12 more
core   +1 more source

RNAhybrid: microRNA target prediction easy, fast, and flexible

open access: yes, 2006
Krüger J, Rehmsmeier M. RNAhybrid: microRNA target prediction easy, fast, and flexible. Nucleic Acids Research.
Krüger, Jan, Rehmsmeier, Marc
core   +1 more source

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