Decoding transcription and microRNA-mediated translation control in Drosophila development [PDF]
The spatio-temporal regulation of gene expression lies at the heart of animal development. In this article we present an overview of our recent work to apply systems biological approaches to the study of transcription and microRNA-mediated translation ...
Gaul, Ulrike
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CHO microRNA engineering is growing up : recent successes and future challenges [PDF]
microRNAs with their ability to regulate complex pathways that control cellular behavior and phenotype have been proposed as potential targets for cell engineering in the context of optimization of biopharmaceutical production cell lines, specifically of
Grillari, Johannes +12 more
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Evaluation of Stem-Loop Reverse Transcription and Poly-A Tail Extension in MicroRNA Analysis of Body Fluids [PDF]
MicroRNA has been demonstrated to be a viable tool for body fluid identification purposes in forensic casework. Stem-loop reverse transcription (slRT) is regularly used for cDNA synthesis from mature miRNA, along with poly-A tail extension.
Williams, Graham A. +3 more
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Functional microRNA high throughput screening reveals miR-9 as a central regulator of liver oncogenesis by affecting the PPARA-CDH1 pathway [PDF]
Background: Hepatocellular carcinoma (HCC) is the second leading cause of cancer-related deaths, reflecting the aggressiveness of this type of cancer and the absence of effective therapeutic regimens.
Drakaki, A +23 more
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Characterisation of body fluid specific microRNA markers by capillary electrophoresis [PDF]
The characterisation of RNA molecules for the purpose of body fluid identification is currently a major field in forensic genetics; with a great deal of effort going towards the analysis of messenger RNA (mRNA).
World, Damien +6 more
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Body fluid mixtures; resolution using forensic microRNA analysis [PDF]
Body fluid identification is a crucial aspect of forensic biology; particularly in sexual assaults which is usually characterised as a mixture of body fluids.
World, Damien +5 more
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Mechanisms of microRNA mediated gene silencing in C. elegans [PDF]
Mechanisms of microRNA mediated gene silencing in C. elegans Xavier Ding Dissertation abstract microRNAs (miRNAs) are a large family of small non-coding RNAs, which post-transcriptionally repress numerous genes; a type of regulation which is ...
Ding, Xavier
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MMpred: functional miRNA – mRNA interaction analyses by miRNA expression prediction [PDF]
Background: MicroRNA (miRNA) directed gene repression is an important mechanism of posttranscriptional regulation. Comprehensive analyses of how microRNA influence biological processes requires paired miRNA-mRNA expression datasets.
Wilson, Paul +5 more
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miREE: miRNA Recognition Elements Ensemble [PDF]
Background Computational methods for microRNA target prediction are a fundamental step to understand the miRNA role in gene regulation, a key process in molecular biology. In this paper we present miREE, a novel microRNA target prediction tool.
Enrico Macii +12 more
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RNAhybrid: microRNA target prediction easy, fast, and flexible
Krüger J, Rehmsmeier M. RNAhybrid: microRNA target prediction easy, fast, and flexible. Nucleic Acids Research.
Krüger, Jan, Rehmsmeier, Marc
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