Results 1 to 10 of about 651,129 (303)

Evaluation of the utility of a nomogram for predicting lymph node metastasis in T1 colorectal cancer in shared decision-making in clinical practice: a survey-based study [PDF]

Annals of Coloproctology
Purpose In 2019, we reported a novel nomogram to predict lymph node metastasis (LNM) in T1 colorectal cancer. Herein, we conducted a survey-based study to evaluate the clinical utility of this nomogram in determining the need for additional surgery after
Hyeon Seung Kim, Kyung Su Han, Min Wan Lee, Dae Kyung Sohn, Chang Won Hong, Dong Woon Lee, Kiho You, Sung Chan Park, Byung Chang Kim, Bun Kim, Jae Hwan Oh   +10 more
doaj   +1 more source

Programmed Death Ligand-1 expression in stage II colon cancer - experiences from a nationwide populationbased cohort

BMC Cancer, 2019
Background Patients suffering from high risk stage II colon cancer (CC) may benefit from adjuvant onco-therapy, but additional prognostic markers are needed for better treatment stratification.
Ann C. Eriksen, Flemming B. Sørensen, Jan Lindebjerg, Henrik Hager, René dePont Christensen, Sanne Kjær-Frifeldt, Torben F. Hansen   +6 more
doaj   +1 more source

Identification of PANoptosis associated lncRNAs associated with clinical prognosis and immune infiltration microenvironment in colon adenocarcinoma

Discover Oncology
Early diagnosis and disease management based on risk stratification have a very positive impact on colon adenocarcinoma (COAD) prognosis. It is of positive significance to further explore risk stratification of COAD patients and identify predictive ...
Yangyang Wang, Shihui Zhao, Songtao Du, Tianyi Xia, Liqiang Song, Mingyu Xia, Bomiao Zhang   +6 more
doaj   +1 more source

Long-term clinical outcomes after high and low ligations with lymph node dissection around the root of the inferior mesenteric artery in patients with rectal cancer [PDF]

Annals of Coloproctology
Purpose This study aimed to evaluate the long-term clinical outcomes based on the ligation level of the inferior mesenteric artery (IMA) in patients with rectal cancer.
Min Wan Lee, Sung Sil Park, Kiho You, Dong Eun Lee, Dong Woon Lee, Sung Chan Park, Kyung Su Han, Dae Kyung Sohn, Chang Won Hong, Bun Kim, Byung Chang Kim, Hee Jin Chang, Dae Yong Kim, Jae Hwan Oh   +13 more
doaj   +1 more source

A preoperative MRI pelvic multiparameter nomogram for predicting sphincter preservation and operative difficulty in laparoscopic total mesorectal excision for ultra-low rectal cancer

BMC Surgery
Background Sphincter preservation (SP) during laparoscopic total mesorectal excision (LaTME) for low rectal cancer is challenged by a deep, narrow pelvis. Robust, MRI-based predictors for both SP success and operative difficulty are lacking.
Haipeng Jin, Qian Zhang, Longhai Feng, Rongbiao Ying, Haixing Ju   +4 more
doaj   +1 more source

Multiple rapidly growing desmoid tumors that were difficult to distinguish from recurrence of rectal cancer

World Journal of Surgical Oncology, 2017
Background Intra-abdominal desmoid tumors are usually slow growing and solitary, but multifocal desmoid tumors develop on rare occasions. Diagnosing desmoid tumors before histological examination of a surgical biopsy is often difficult. In particular, if
Koki Nakanishi, Dai Shida, Shunsuke Tsukamoto, Hiroki Ochiai, Junichi Mazaki, Hirokazu Taniguchi, Yukihide Kanemitsu   +6 more
doaj   +1 more source

Effect of sex differences on the emergence of ctDNA RAS mutations in RAS wild-type colorectal cancer

Scientific Reports
In some cases of RAS wild-type metastatic colorectal cancer (mCRC), mutant RAS may emerge during chemotherapy. This study aimed to identify the clinicopathological factors associated with the emergence of RAS mutations during treatment.
Kenta Iguchi, Mamoru Uchiyama, Masahiro Asari, Koji Numata, Manabu Shiozawa   +4 more
doaj   +1 more source

Adjuvant chemotherapy for rectal cancer with complete pathological response (pCR) may not be necessary: a pooled analysis of 5491 patients

Cancer Cell International, 2019
Background It is recommended postoperative adjuvant chemotherapy for all rectal cancers undergoing neo-chemoradiotherapy regardless of the final yield pathology.
Xiang Hu, Ya-Qi Li, Xiao-ji Ma, Long Zhang, San-Jun Cai, Jun-Jie Peng   +5 more
doaj   +1 more source

FOXE1 represses cell proliferation and Warburg effect by inhibiting HK2 in colorectal cancer

Cell Communication and Signaling, 2020
Background Low expression of FOXE1, a member of Forkhead box (FOX) transcription factor family that plays vital roles in cancers, contributes to poor prognosis of colorectal cancer (CRC) patients.
Weixing Dai, Xianke Meng, Shaobo Mo, Wenqiang Xiang, Ye Xu, Long Zhang, Renjie Wang, Qingguo Li, Guoxiang Cai   +8 more
doaj   +1 more source

Neoadjuvant FOLFOXIRI chemotherapy with or without camrelizumab in the treatment of locally advanced rectal cancer: a retrospective cohort study

npj Precision Oncology
Standard neoadjuvant chemoradiotherapy for locally advanced rectal cancer (LARC) is associated with significant toxicity and limited pathological responses.
Yanlong Liu, Shihui Zhao, Fenqi Du, Songtao Du, Liqiang Song, Tianyi Xia, Bomiao Zhang, Binbin Cui   +7 more
doaj   +1 more source