Results 31 to 40 of about 648,498 (303)

Can the Single-stapling Technique Following Intersphincteric Resection with Transanal Total Mesorectal Excision Become the New Standard Anastomosis?

Journal of the Anus, Rectum and Colon, 2023
For transanal total mesorectal excision (TaTME), the indication for single-stapling technique (SST) has been expanded to include lower anastomosis, even in intersphincteric resection (ISR).
Daichi Kitaguchi, Hiro Hasegawa, Koji Ando, Koji Ikeda, Yuichiro Tsukada, Yuji Nishizawa, Masaaki Ito   +6 more
doaj   +1 more source

TERC polymorphisms are associated both with susceptibility to colorectal cancer and with longer telomeres. [PDF]

, 2011
Shorter telomeres have been associated with increased risk of malignancy, including colorectal cancer (CRC). Telomere length is heritable and may be an intermediate phenotype linked to genetic susceptibility to ...
Tomlinson, IP, A M Jones, Beggs, A. D., Jones, A. M., M Walker, Jones, A.M., Dunlop, MG, Beggs, A.D., Tenesa, A., A D Beggs, Kerr, D, A Zauber, A Tenesa, Hodgson, S. V., Walker, M., M Bertagnolli, R Midgley, Carvajal-Carmona, L, Dunlop, Malcolm, Tenesa, Albert, Tenesa, A, Kerr, D., Jones, AM, Beggs, AD, M G Dunlop, Kerr, David, Jones, A M, Tomlinson, IPM, Carvajal-Carmona, L., Campbell, H.; id_orcid, Tomlinson, I P M, S Ballereau, Tomlinson, I. P. M., Zauber, A., S V Hodgson, Campbell, H, H Campbell, Farrington, S., Hodgson, SV, Ballereau, S., Campbell, H., Midgley, Rachel, Walker, M, S Farrington, I P M Tomlinson, Dunlop, M G, K Howarth, Farrington, S.; id_orcid, Howarth, K., Ballereau, S, Hodgson, S.V., Bertagnolli, M., Tomlinson, I.P., Beggs, A D; id_orcid, Midgley, R., D Kerr, Bertagnolli, M, L Carvajal-Carmona, Hodgson, S V, Dunlop, M. G., Midgley, R, Zauber, A, Howarth, K, Farrington, S   +63 more
core   +1 more source

Anticipated regret to increase uptake of colorectal cancer screening (ARTICS):a randomised controlled trial [PDF]

, 2015
Screening is important for early detection of colorectal cancer. Our aim was to determine whether a simple anticipated regret (AR) intervention could increase uptake of colorectal cancer screening. A randomised controlled trial of a simple, questionnaire-
Brownlee, Linda A., Steele, Robert J. C., O'Carroll, Ronan E., Steele, Robert, Chambers, Julie A., Chambers, Julie, Brownlee, Linda, Libby, Gillian, Steele, Robert J.C., O'Carroll, Ronan   +9 more
core   +1 more source

Monitoring the effect of first line treatment in RAS/RAF mutated metastatic colorectal cancer by serial analysis of tumor specific DNA in plasma

Journal of Experimental & Clinical Cancer Research, 2018
Background Precision medicine calls for an early indicator of treatment efficiency. Circulating tumor DNA (ctDNA) is a promising marker in this setting. Our prospective study explored the association between disease development and change of ctDNA during
C. B. Thomsen, T. F. Hansen, R. F. Andersen, J. Lindebjerg, L. H. Jensen, A. Jakobsen   +5 more
doaj   +1 more source

Establishment and validation of a novel nomogram incorporating clinicopathological parameters into the TNM staging system to predict prognosis for stage II colorectal cancer

Cancer Cell International, 2020
Background Survival outcomes are significantly different in stage II colorectal cancer (CRC) patients with diverse clinicopathological features. The objective of this study is to establish a credible prognostic nomogram incorporating easily obtained ...
Shaobo Mo, Zheng Zhou, Yaqi Li, Xiang Hu, Xiaoji Ma, Long Zhang, Sanjun Cai, Junjie Peng   +7 more
doaj   +1 more source

Bevacizumab plus Irinotecan-Based Regimens in the Treatment of Metastatic Colorectal Cancer [PDF]

, 2010
Objectives: Bevacizumab is a monoclonal antibody that directly inhibits vascular endothelial growth factor, a key regulator of angiogenesis. Bevacizumab significantly improves progression-free and/or overall survival in metastatic colorectal cancer in ...
Volker Heinemann, Paulo M. Hoff, Heinemann, Volker, Hoff, Paulo M.   +3 more
core   +1 more source

Size and number of lymph nodes were risk factors of recurrence in stage II colorectal cancer

BMC Cancer, 2023
Background Size and number of lymph nodes (LNs) were reported to be associated with the prognosis of stage II colorectal cancer (CRC). The purpose of this study was to determine the prognostic role of the size of LNs (SLNs) measured by computer ...
Shanyou Tong, Menglei Li, Yichao Bao, Long Zhang, Ping Lu, Tong Tong, Junjie Peng   +6 more
doaj   +1 more source

Shorter survival in adolescent and young adult patients, compared to adult patients, with stage IV colorectal cancer in Japan

BMC Cancer, 2018
Background The incidence of colorectal cancer in adolescent and young adult patients is increasing. However, survival and clinical features of young patients, especially those with stage IV disease, relative to adult patients remain unclear. Methods This
Dai Shida, Yuka Ahiko, Taro Tanabe, Takefumi Yoshida, Shunsuke Tsukamoto, Hiroki Ochiai, Atsuo Takashima, Narikazu Boku, Yukihide Kanemitsu   +8 more
doaj   +1 more source

Completeness of case ascertainment and survival time error in English cancer registries: impact on 1-year survival estimates. [PDF]

, 2011
BACKGROUND: It has been suggested that cancer registries in England are too dependent on processing of information from death certificates, and consequently that cancer survival statistics reported for England are systematically biased and too low ...
Riaz, SP, Holmberg, L, Moller, H.; id_orcid, Hanchett, N., N Hanchett, Richards, S., Robinson, D, L Holmberg, H Møller, S Richards, Riaz, S. P., Richards, S, Holmberg, Lars,, M Lüchtenborg, Riaz, S P, Møller, H, Hanchett, N, Lüchtenborg, M, Lüchtenborg, Margreet, Holmberg, L., S P Riaz, D Robinson, Robinson, D.   +22 more
core   +1 more source

Association between TAS2R38 gene polymorphisms and colorectal cancer risk [PDF]

, 2011
Molecular sensing in the lingual mucosa and in the gastro-intestinal tract play a role in the detection of ingested harmful drugs and toxins. Therefore, genetic polymorphisms affecting the capability of initiating these responses may be critical for the ...
Stemmler, Susanne, Novotny, Jan, Steinke, Verena, Vodicka, Pavel, Morak, Monika, Hemminki, Kari, Pardini, Barbara, Engel, Christoph, Canzian, Federico, Schackert, Hans K., Naccarati, Alessio, Vodickova, Ludmila, Görgens, Heike, Propping, Peter, Barale, Roberto, Büttner, Reinhard, Försti, Asta, Carrai, Maura, Betz, Beate, Holinski-Feder, Elke, Stein, Angelika, Kloor, Matthias, Rahner, Nils, Campa, Daniele   +23 more
core   +1 more source