Results 21 to 30 of about 5,919,627 (334)

Temporal trends in mode, site and stage of presentation with the introduction of colorectal cancer screening: a decade of experience from the West of Scotland [PDF]

open access: yes, 2015
background:  Population colorectal cancer screening programmes have been introduced to reduce cancer-specific mortality through the detection of early-stage disease.
A Downing   +28 more
core   +5 more sources

Favorable short-term oncologic outcomes following laparoscopic surgery for small T4 colon cancer: a multicenter comparative study

open access: yesWorld Journal of Surgical Oncology, 2020
Background Laparoscopic surgery for T4 colon cancer may be safe in selected patients. We hypothesized that small tumor size might preoperatively predict a good laparoscopic surgery outcome. Herein, we compared the clinicopathologic and oncologic outcomes
Sung Sil Park   +12 more
doaj   +1 more source

A review of 14 cases of perianal Paget’s disease: characteristics of anorectal cancer with pagetoid spread

open access: yesWorld Journal of Surgical Oncology, 2023
Background Perianal Paget’s disease (PPD) is an intraepithelial invasion of the perianal skin and is frequently associated with underlying anorectal carcinoma.
Jun Imaizumi   +5 more
doaj   +1 more source

The Consensus Molecular Subtypes of Colorectal Cancer

open access: yesNature Medicine, 2015
Colorectal cancer (CRC) is a frequently lethal disease with heterogeneous outcomes and drug responses. To resolve inconsistencies among the reported gene expression–based CRC classifications and facilitate clinical translation, we formed an international
J. Guinney   +39 more
semanticscholar   +1 more source

Wnt signaling in colorectal cancer: pathogenic role and therapeutic target

open access: yesMolecular Cancer, 2022
Background The Wnt signaling pathway is a complex network of protein interactions that functions most commonly in embryonic development and cancer, but is also involved in normal physiological processes in adults.
Hui-Ying Zhao   +7 more
semanticscholar   +1 more source

HOXD8 exerts a tumor-suppressing role in colorectal cancer as an apoptotic inducer [PDF]

open access: yes, 2017
Homeobox (HOX) genes are conserved transcription factors which determine the anterior-posterior body axis patterning. HOXD8 is a member of HOX genes deregulated in several tumors such as lung carcinoma, neuroblastoma, glioma and colorectal cancer (CRC ...
Mansour, Mohammed A., Senga, Takeshi
core   +1 more source

Controlling nutritional status (CONUT) score as a preoperative risk assessment index for older patients with colorectal cancer

open access: yesBMC Cancer, 2019
Background Assessment of preoperative general condition to predict postoperative outcomes is important, particularly in older patients who typically suffer from various comorbidities and exhibit impaired functional status.
Yuka Ahiko   +8 more
doaj   +1 more source

Transanal Total Mesorectal Excision for Rectal Cancer: Toward Standardization of the Surgical Technique

open access: yesJournal of the Anus, Rectum and Colon, 2023
Laparoscopic surgery is widely used for rectal cancer; however, this technique is challenging due to tapering of the mesorectum in the pelvis, and the forward angle of the distal rectum, which renders this part of the rectum less accessible from the ...
Daichi Kitaguchi   +6 more
doaj   +1 more source

Attitude to Secondary Prevention and Concerns about Colonoscopy Are Independent Predictors of Acceptance of Screening Colonoscopy [PDF]

open access: yes, 2010
Background: Colonoscopy in combination with endoscopic polypectomy has been shown to be an efficient measure for reducing colorectal cancer incidence.
Bühner, Markus   +3 more
core   +1 more source

A Review of Colorectal Cancer in Terms of Epidemiology, Risk Factors, Development, Symptoms and Diagnosis

open access: yesCancers, 2021
Simple Summary According to the available data, colorectal cancer (CRC) is one of the most common malignant neoplasms. Depending on the location, type of cancer or gender, it is ranked 2nd to 4th in terms of incidence in the world.
T. Sawicki   +5 more
semanticscholar   +1 more source

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