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Colorectal cancer statistics, 2017
Colorectal cancer (CRC) is one of the most common malignancies in the United States. Every 3 years, the American Cancer Society provides an update of CRC incidence, survival, and mortality rates and trends.
R. Siegel +6 more
semanticscholar +3 more sources
In the United States, colorectal cancer (CRC) is the third most common cancer diagnosed among men and women and the second leading cause of death from cancer.
B. Levin +13 more
semanticscholar +3 more sources
This article provides an update on the global cancer burden using the GLOBOCAN 2020 estimates of cancer incidence and mortality produced by the International Agency for Research on Cancer.
H. Sung +6 more
semanticscholar +1 more source
Metastatic colorectal cancer: mechanisms and emerging therapeutics.
Metastatic colorectal cancer (mCRC) remains a lethal disease with an approximately 14% 5-year survival rate. While early-stage colorectal cancer (CRC) can be cured by surgery with or without adjuvant chemotherapy, mCRC cannot be eradicated due to a large
A. Shin, F. Giancotti, A. Rustgi
semanticscholar +1 more source
This is the final version of the article. Available from the publisher via the DOI in this record. ; This is one of a series of occasional articles highlighting conditions that may be more common than many doctors realise or may be missed at first presentation.
Hamilton, W, Coleman, MG, Rubin, G
openaire +3 more sources
Activation of miR-500a-3p/CDK6 axis suppresses aerobic glycolysis and colorectal cancer progression
Background Colorectal cancer (CRC) is one of the lethal cancers with a high mortality rate worldwide and understanding the mechanisms behind its progression is critical for improving patients’ prognosis and developing therapeutics.
Yu Liu +10 more
doaj +1 more source
Effect of Colonoscopy Screening on Risks of Colorectal Cancer and Related Death.
BACKGROUND Although colonoscopy is widely used as a screening test to detect colorectal cancer, its effect on the risks of colorectal cancer and related death is unclear.
M. Bretthauer +20 more
semanticscholar +1 more source
Shanghai plan for early screening, diagnosis and treatment of colorectal cancer (2023 edition) [PDF]
Colorectal cancer is a common malignant tumor in China. At present, the incidence rate and the mortality rate of colorectal cancer in China are on the rise.
Colorectal Cancer Special Committee of Shanghai Anti-Cancer Association
doaj +1 more source
BH3 mimetic ABT-737 sensitizes colorectal cancer cells to ixazomib through MCL-1 downregulation and autophagy inhibition. [PDF]
The proteasome inhibitor MLN9708 is an orally administered drug that is hydrolyzed into its active form, MLN2238 (ixazomib). Compared with Bortezomib, MLN2238 has a shorter proteasome dissociation half-life and a lower incidence and severity of ...
Barkhouse, Darryll +7 more
core +2 more sources
Downregulation of plasma MiR-142-3p and MiR-26a-5p in patients with colorectal carcinoma [PDF]
Background: Colorectal cancer is one of the most commonly diagnosed cancers and cancer- related death worldwide. Identification of new specific biomarkers could be helpful to detection of this malignancy.
Asadi, J. +9 more
core +1 more source

