Results 41 to 50 of about 3,531,408 (290)

Tumour inflammatory infiltrate predicts survival following curative resection for node-negative colorectal cancer [PDF]

, 2009
<b>Background</b>: A pronounced tumour inflammatory infiltrate is known to confer a good outcome in colorectal cancer. Klintrup and colleagues reported a structured assessment of the inflammatory reaction at the invasive margin scoring low ...
Roxburgh, C.S., McMillan, D.C., Horgan, P.G., Salmond, J.M., Oien, K.A.   +4 more
core   +1 more source

Impact of Radiation Therapy on Physical and Psychosocial Health of Adolescents and Young Adults: A Joint Report From the Children's Oncology Group AYA and Radiation Oncology Committees

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Rates of cancer among adolescents and young adults (AYA), age 15–39 years, are increasing. Consequently, radiation oncologists are treating more AYAs who have diagnoses spanning both pediatric and adult practices. Compared to pediatric and older adult patients, AYAs face a unique set of challenges.
Hesham Elhalawani, Rachel K. Peterson, Avani D. Rao, Laurie J. McKenzie, Ahmed Magdy Elmotayam, Leslie Chang, Michael Roth, Susan L. McGovern   +7 more
wiley   +1 more source

Family history of colorectal cancer: a determinant of advanced adenoma stage or adenoma multiplicity?

, 2009
A family history of colorectal cancer may increase colorectal cancer risk by influencing adenoma growth or enhancing the formation of new lesions. Data of men from the prospective Health Professionals Follow-Up Study who underwent an endoscopy between ...
Wu, Kana, Kana Wu, Pieter van 't Veer, Wark, P.A., Charles F. Fuchs, Veer, P., van 't, Fuchs, C.F., Fuchs, Charles F, van 't Veer, P., Fuchs, Charles F., Wu, K., Giovannucci, Edward L., Wark, Petra A, Petra A. Wark, Giovannucci, Edward L, Wark, Petra A.; id_orcid, Edward L. Giovannucci, Giovannucci, E.L., van 't Veer, Pieter   +18 more
core   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Increased colorectal cancer incidence in obligate carriers of heterozygous mutations in MUTYH

, 2002
Background & Aims: MUTYH-associated polyposis (MAP) is an autosomal recessive disorder caused by mutations in the MUTYH gene. Patients with MAP are at extremely high risk of colorectal cancer, but the risks of colorectal and other cancers in ...
Jones, Natalie, Maher, Eamonn, Sampson, Julian Roy, Edwards, Emma, Christian, Daria, Evans, D Gareth, Vasen, Hans F., Wark, Petra A., Sampson, Julian R, Eccles, Diana, Aretz, Stefan, Nielsen, Maartje, Maher, Eamonn R., Wark, Petra A, Vogt, Stefanie, Wark, Petra A.; id_orcid, Hes, Frederik J, Hes, Frederik J., Evans, D. Gareth, Sampson, Julian R., Vasen, Hans F, Maher, Eamonn R   +21 more
core   +1 more source

A cohort study of the recovery of health and wellbeing following colorectal cancer (CREW study): protocol paper [PDF]

, 2012
Background: the number of people surviving colorectal cancer has doubled in recent years. While much of the literature suggests that most people return to near pre-diagnosis status following surgery for colorectal cancer, this literature has largely ...
Foster, Claire L., Fenlon Deborah, Corner Jessica, Jessica Corner, Winter Jane, Smith, Peter, Corner, Jessica L, Richardson Alison, Smith Peter, Deborah Fenlon, Alison Richardson, Jane Winter, Winter, Jane, Foster Claire, Claire Foster, Fenlon, Deborah R., Addington-Hall, Julia M., Addington-Hall Julia, Richardson, Alison, Julia Addington-Hall, Peter Smith   +20 more
core   +2 more sources

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Alcohol consumption, alcohol dehydrogenase 3 polymorphism, and colorectal adenomas. [PDF]

, 2003
Alcohol is a probable risk factor with regard to colorectal neoplasm and is metabolized to the carcinogen acetaldehyde by the genetically polymorphic alcohol dehydrogenase 3 (ADH3) enzyme.
Ocké, Marga C, Tiemersma, Edine W, Wark, Petra A, Kampman, Ellen, Bunschoten, Annelies, Otten, Marten H, Kok, Frans J   +6 more
core   +4 more sources

Chemoprevention of colorectal cancer [PDF]

The International Journal of Biological Markers, 2003
NA
Biasco G., Di Marco M., Pantaleo M. A.
openaire   +3 more sources

Population screening for colorectal cancer means getting FIT:the past, present, and future of colorectal cancer screening using the fecal immunochemical test for hemoglobin (FIT) [PDF]

, 2014
Fecal immunochemical tests for hemoglobin (FIT) are changing the manner in which colorectal cancer (CRC) is screened. Although these tests are being performed worldwide, why is this test different from its predecessors?
Halloran, SP, Fraser, Callum G., Fraser, CG, Young, Graeme P., Halloran, Stephen P., Allison, JE, Allison, James E., Young, GP   +7 more
core   +1 more source