Results 1 to 10 of about 340,419 (317)

The impact of plasmid on regeneration and expression efficiencies of gfp gene in tobacco (Nicotiana tabacum L.)

open access: yesActa Agriculturae Slovenica, 2014
Tobacco leaf explants were transformed by bacteria Agrobacterium tumefaciens (A. t.) and plasmid pBIN mgfp5-ER, which has a single copy of the green fluorescent gfp gene and A. t.-pART27 2mgfp5-ER, which has two copies of the gfp gene. Both plasmids have
Niko PAVLIN, Zlata LUTHAR
doaj   +1 more source

Astrocyte deletion of Bmal1 alters daily locomotor activity and cognitive functions via GABA signalling

open access: yesNature Communications, 2017
Core clock genes, such asBmal1, are expressed in astrocytes, but their contribution to the timekeeping system is unknown. Barca-Mayo et al. report that deletion of Bmal1in Glast+ astrocytes alters the neuronal clock through GABA signalling, leading to ...
Olga Barca-Mayo   +5 more
doaj   +1 more source

DGCR8 Promotes Neural Progenitor Expansion and Represses Neurogenesis in the Mouse Embryonic Neocortex

open access: yesFrontiers in Neuroscience, 2018
DGCR8 and DROSHA are the minimal functional core of the Microprocessor complex essential for biogenesis of canonical microRNAs and for the processing of other RNAs. Conditional deletion of Dgcr8 and Drosha in the murine telencephalon indicated that these
Nadin Hoffmann   +4 more
doaj   +1 more source

Dissimilar Appearances Are Deceptive–Common microRNAs and Therapeutic Strategies in Liver Cancer and Melanoma

open access: yesCells, 2020
In this review, we summarize the current knowledge on miRNAs as therapeutic targets in two cancer types that were frequently described to be driven by miRNAs—melanoma and hepatocellular carcinoma (HCC).
Lisa Linck-Paulus   +3 more
doaj   +1 more source

The importance of training in contemporary organizations

open access: yesMенаџмент у хотелијерству и туризму, 2019
This paper describes the concepts of training and career development for employees, level of knowledge of workers, the profit that some companies had from continuous training, and the way in which an organizational psychologist, with the support of ...
Ana Slavković, Vukan Slavković
doaj   +1 more source

NGR4 and ERBB4 as Promising Diagnostic and Therapeutic Targets for Metabolic Disorders

open access: yesFrontiers in Bioscience-Elite, 2023
Obese individuals are at high risk for developing type 2 diabetes mellitus, cardiovascular diseases, and nonalcoholic fatty liver disease. The aim of this review was to analyze the scientific literature and databases to reveal the fundamental role of ...
Maria Vulf   +10 more
doaj   +1 more source

ŽUPANČIČEVA ZAPUŠČINA IN NJEGOVA OSEBNA KNJIŽNICA

open access: yesKnjižnica, 2015
Zapuščina književnika Otona Župančiča, ki jo je Mestnemu muzeju Ljubljana leta 1985 z darilno pogodbo izročila umetnikova družina, sodi med redke tako obsežne in raznovrstne umetniške zapuščine.
Dragica Trobec Zadnik   +1 more
doaj   +1 more source

MicroRNA-6744-5p promotes anoikis in breast cancer and directly targets NAT1 enzyme

open access: yesCancer Biology & Medicine, 2020
Objective: Anoikis is apoptosis that is induced when cells detach from the extracellular matrix and neighboring cells. As anoikis serves as a regulatory barrier, cancer cells often acquire resistance towards anoikis during tumorigenesis to become ...
Sharan Malagobadan   +2 more
doaj   +1 more source

Urinary metals and maternal circulating extracellular vesicle microRNA in the MADRES pregnancy cohort

open access: yesEpigenetics, 2022
Exposure to metals increases risk for pregnancy complications. Extracellular vesicle (EV) miRNA contribute to maternal-foetal communication and are dysregulated in pregnancy complications.
Caitlin G. Howe   +8 more
doaj   +1 more source

Assessment of reporting quality of abstracts of systematic reviews with meta-analysis using PRISMA-A and discordance in assessments between raters without prior experience

open access: yesBMC Medical Research Methodology, 2019
Background Reporting quality of systematic reviews’ (SRs) abstracts is important because this is often the only information about a study that readers have. The aim of this study was to assess adherence of SR abstracts in the field of anesthesiology with
Katarina Maticic   +2 more
doaj   +1 more source

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