Results 1 to 10 of about 466,683 (254)
The expression profile of exosomal miRNAs in cervical cancer cells (HeLa) compared to normal cells and evaluating the key genes related to them [PDF]
Majallah-i Zanān, Māmā̓ī va Nāzā̓ī-i Īrān, 2023 Introduction: Cervical cancer is the fourth most common cancer among women worldwide and is a heterogeneous disease. The exosomal miRNAs could be applied as diagnostic biomarkers and therapeutic targets in cervical cancer. The present study was performed
Marzieh Naderi Boldaji +2 more
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High-throughput sequencing analysis of mirna expression in embryonic chicken breast muscle [PDF]
Kafkas Universitesi Veteriner Fakültesi Dergisi, 2021 The embryonic period is a critical period for the development of muscle and adipose tissue in chickens. MicroRNAs (miRNAs) have been shown to play important roles in various biological processes, but little is known about miRNAs in chicken embryos.
Lei ZHANG +3 more
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A Xenotransplant Model of Human Brain Tumors in Wild-Type Mice
iScience, 2020 Summary: The development of adequate model systems to study human malignancies is crucial for basic and preclinical research. Here, we exploit the “immune-privileged” developmental time window to achieve orthotopic xenotransplantation of human brain ...
Nadin Hoffmann +5 more
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Scientific Reports, 2023 In mammals, the suprachiasmatic nucleus of the hypothalamus is the master circadian pacemaker that synchronizes the clocks in the central nervous system and periphery, thus orchestrating rhythms throughout the body.
Lidia Giantomasi +6 more
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Glial Bmal1 role in mammalian retina daily changes
Scientific Reports, 2022 Visual information processing in the retina requires the rhythmic expression of clock genes. The intrinsic retinal circadian clock is independent of the master clock located in the hypothalamic suprachiasmatic nucleus and emerges from retinal cells ...
Serena Riccitelli +8 more
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A novel strategy for orthogonal genetic regulation on different RNA targeted loci simultaneously
RNA Biology, 2022 No current RNA-targeted interference tools have been reported to simultaneously up and down-regulate different gene expressions. Here we characterized an RNA-targeted genetic regulatory strategy composed of a flap endonuclease 1 (FEN1) and specific mis ...
Yongjian Guo +9 more
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The singular world of singular cardinals [PDF]
, 2014 The article uses two examples to explore the statement that, contrary to the common wisdom, the properties of singular cardinals are actually more intuitive than those of the regular ...
Dzamonja, Mirna
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miR-34 – A microRNA Replacement Therapy Is Headed to the Clinic
Frontiers in Genetics, 2012 MicroRNA-34 is a master regulator of tumor suppression. It is downregulated in numerous cancers and inhibits malignant growth by repressing genes involved in various oncogenic signaling pathways.
Andreas G Bader
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Mechanisms of non-coding RNA-modulated alternative splicing in cancer
RNA Biology, 2022 Alternative splicing (AS) is a common and pivotal process for eukaryotic gene expression regulation, which enables a precursor RNA to produce multiple transcript variants with diverse cellular functions.
Xiaolin Wang +6 more
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miRBase Tracker : keeping track of microRNA annotation changes [PDF]
, 2014 Since 2002, information on individual microRNAs (miRNAs), such as reference names and sequences, has been stored in miRBase, the reference database for miRNA annota- tion.
Anckaert, Jasper +10 more
core +2 more sources