Results 41 to 50 of about 340,419 (317)

Construction of lncRNA-miRNA-mRNA regulatory network.

open access: yes, 2022
(A) Predicted lncRNA-miRNA-mRNA regulatory network. LncRNAs with at least 10 predicted binding sites for at least 1 miRNA associated with ALV invasion were included.
Mohammad Heidari (6617507)   +7 more
core   +1 more source

Involvement of plasma miRNAs, muscle miRNAs and mitochondrial miRNAs in the pathophysiology of frailty

open access: yesExperimental Gerontology, 2019
Frailty is a geriatric syndrome that leads not only to the loss of physical functions, but also to a generalized decline of the organism and a high risk of disability and dependency. Frailty's detection and management represent important goals for current gerontology.
Iryna, Rusanova   +7 more
openaire   +2 more sources

Mechanisms of action of cytoplasmic microRNAs. Part 5. MicroRNA-mediated silencing caused during translation initiation and post-initiation

open access: yesZdorovʹe Rebenka, 2022
The scientific review considers the mechanisms of action of cytoplasmic microRNAs, namely miRNA-mediated silencing, which is caused during the initiation and post-initiation period of translation.
A.E. Abaturov, V.L. Babуch
doaj   +1 more source

Discrimination between Cancer Cells and DNA-Damaged Cells: Pre-miRNA Region Recognition Based on Hyperbranched Hybrid Chain Reaction Amplification for Simultaneous Sensitive Detection and Imaging of miRNA and Pre-miRNA

open access: yes, 2022
Herein, a novel region recognition of precursor microRNA (Pre-miRNA) based on hyperbranched hybrid chain reaction (HB-HCR) amplification was constructed to effectively eliminate the interference of Pre-miRNA to the mature microRNA (miRNA) by establishing
Zezhou Yang (12878919)   +6 more
core   +1 more source

PIWI-interacting RNAs in neurological and neuropsychiatric disorders and potential for clinical development

open access: yesBrain Organoid and Systems Neuroscience Journal
Neural diseases, including neurological and neuropsychiatric disorders, represent a significant and growing public health burden. While the understanding of the genetic origins of these diseases has advanced considerably in recent years, the underlying ...
Silvia Beatini   +3 more
doaj   +1 more source

Psychological and family factors that influence the occurrence of juvenile delinquency [PDF]

open access: yesSinteze, 2019
In this paper, the aggressiveness and delinquent behaviour of adolescents is placed in the context of developmental turbulence that can be temporary. In the case of a young person who violates legal norms, there may be potential for a healthy personality
Slavković Ana R., Slavković Vukan R.
doaj  

Mechanisms of action of cytoplasmic microRNAs. Part 2. MicroRNA-mediated post-translational silencing

open access: yesZdorovʹe Rebenka, 2022
The scientific review presents the mechanisms of action of cytoplasmic miRNAs, namely miRNA-mediated posttranslational silencing. To write the article, information was searched ­using Scopus, Web of Science, MedLine, PubMed, Google Scho­lar, EMBASE ...
A.E. Abaturov, V.L. Babуch
doaj   +1 more source

miRNA-Seq

open access: yes, 2019
To determine if HuR regulates miRNA biogenesis, we used miRNA-seq for genome-wide miRNA profiling to compare the miRNA profiles in HuR small interfering RNA (siRNA) targeting HuR mRNA (siHuR) transfected IEC-6 intestinal epithelial cells.
Ran Zhuang (383394)
core   +1 more source

Principles of miRNA/miRNA* function in plant MIRNA processing

open access: yesNucleic Acids Research
Abstract MicroRNAs (miRNAs) are essential regulators of gene expression, defined by their unique biogenesis, which requires the precise excision of the small RNA from an imperfect fold-back precursor. Unlike their animal counterparts, plant miRNA precursors exhibit variations in sizes and shapes.
Santiago Rosatti   +6 more
openaire   +4 more sources

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

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