Results 41 to 50 of about 381,652 (306)
Brain Organoid and Systems Neuroscience JournalNeural diseases, including neurological and neuropsychiatric disorders, represent a significant and growing public health burden. While the understanding of the genetic origins of these diseases has advanced considerably in recent years, the underlying ...
Silvia Beatini +3 more
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Zdorovʹe Rebenka, 2022 The scientific review considers the mechanisms of action of cytoplasmic microRNAs, namely miRNA-mediated silencing, which is caused during the initiation and post-initiation period of translation.
A.E. Abaturov, V.L. Babуch
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Principles of miRNA/miRNA* function in plant MIRNA processing
Nucleic Acids ResearchAbstract MicroRNAs (miRNAs) are essential regulators of gene expression, defined by their unique biogenesis, which requires the precise excision of the small RNA from an imperfect fold-back precursor. Unlike their animal counterparts, plant miRNA precursors exhibit variations in sizes and shapes.
Santiago Rosatti +6 more
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Psychological and family factors that influence the occurrence of juvenile delinquency [PDF]
Sinteze, 2019 In this paper, the aggressiveness and delinquent behaviour of adolescents is placed in the context of developmental turbulence that can be temporary. In the case of a young person who violates legal norms, there may be potential for a healthy personality
Slavković Ana R., Slavković Vukan R.
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Zdorovʹe Rebenka, 2022 The scientific review presents the mechanisms of action of cytoplasmic miRNAs, namely miRNA-mediated posttranslational silencing. To write the article, information was searched using Scopus, Web of Science, MedLine, PubMed, Google Scholar, EMBASE ...
A.E. Abaturov, V.L. Babуch
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MiRNAs and miRNA Polymorphisms Modify Drug Response [PDF]
International Journal of Environmental Research and Public Health, 2016 Differences in expression of drug response-related genes contribute to inter-individual variation in drugs’ biological effects. MicroRNAs (miRNAs) are small noncoding RNAs emerging as new players in epigenetic regulation of gene expression at post-transcriptional level.
Li, Mu-Peng +7 more
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Frontiers in ImmunologyIntroductionBovine leukemia virus (BLV) is an oncogenic retrovirus that naturally infects cattle. Once infected, the virus persists indefinitely throughout life at a transcriptionally silent stage.
Cecilia Valeria Pérez +6 more
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The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
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Clinics and PracticeBackground/Objectives: Recently, epigenetic mechanisms have been recognized as crucial in atopic dermatitis development. The emphasis of this research was on expanding existing knowledge about the epigenetic aspects of atopic dermatitis, as well as identifying new molecules that could serve as disease biomarkers.
Sanja Jakovljevic +4 more
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miREE: miRNA Recognition Elements Ensemble [PDF]
, 2011 Background Computational methods for microRNA target prediction are a fundamental step to understand the miRNA role in gene regulation, a key process in molecular biology. In this paper we present miREE, a novel microRNA target prediction tool.
Enrico Macii +12 more
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