Results 21 to 30 of about 254,758 (249)

Dissimilar Appearances Are Deceptive–Common microRNAs and Therapeutic Strategies in Liver Cancer and Melanoma

open access: yesCells, 2020
In this review, we summarize the current knowledge on miRNAs as therapeutic targets in two cancer types that were frequently described to be driven by miRNAs—melanoma and hepatocellular carcinoma (HCC).
Lisa Linck-Paulus   +3 more
doaj   +1 more source

The importance of training in contemporary organizations

open access: yesMенаџмент у хотелијерству и туризму, 2019
This paper describes the concepts of training and career development for employees, level of knowledge of workers, the profit that some companies had from continuous training, and the way in which an organizational psychologist, with the support of ...
Ana Slavković, Vukan Slavković
doaj   +1 more source

NGR4 and ERBB4 as Promising Diagnostic and Therapeutic Targets for Metabolic Disorders

open access: yesFrontiers in Bioscience-Elite, 2023
Obese individuals are at high risk for developing type 2 diabetes mellitus, cardiovascular diseases, and nonalcoholic fatty liver disease. The aim of this review was to analyze the scientific literature and databases to reveal the fundamental role of ...
Maria Vulf   +10 more
doaj   +1 more source

MiRNAs and miRNA Polymorphisms Modify Drug Response [PDF]

open access: yesInternational Journal of Environmental Research and Public Health, 2016
Differences in expression of drug response-related genes contribute to inter-individual variation in drugs’ biological effects. MicroRNAs (miRNAs) are small noncoding RNAs emerging as new players in epigenetic regulation of gene expression at post-transcriptional level.
Li, Mu-Peng   +7 more
openaire   +2 more sources

Assessment of reporting quality of abstracts of systematic reviews with meta-analysis using PRISMA-A and discordance in assessments between raters without prior experience

open access: yesBMC Medical Research Methodology, 2019
Background Reporting quality of systematic reviews’ (SRs) abstracts is important because this is often the only information about a study that readers have. The aim of this study was to assess adherence of SR abstracts in the field of anesthesiology with
Katarina Maticic   +2 more
doaj   +1 more source

MicroRNA-6744-5p promotes anoikis in breast cancer and directly targets NAT1 enzyme

open access: yesCancer Biology & Medicine, 2020
Objective: Anoikis is apoptosis that is induced when cells detach from the extracellular matrix and neighboring cells. As anoikis serves as a regulatory barrier, cancer cells often acquire resistance towards anoikis during tumorigenesis to become ...
Sharan Malagobadan   +2 more
doaj   +1 more source

Urinary metals and maternal circulating extracellular vesicle microRNA in the MADRES pregnancy cohort

open access: yesEpigenetics, 2022
Exposure to metals increases risk for pregnancy complications. Extracellular vesicle (EV) miRNA contribute to maternal-foetal communication and are dysregulated in pregnancy complications.
Caitlin G. Howe   +8 more
doaj   +1 more source

ŽUPANČIČEVA ZAPUŠČINA IN NJEGOVA OSEBNA KNJIŽNICA

open access: yesKnjižnica, 2015
Zapuščina književnika Otona Župančiča, ki jo je Mestnemu muzeju Ljubljana leta 1985 z darilno pogodbo izročila umetnikova družina, sodi med redke tako obsežne in raznovrstne umetniške zapuščine.
Dragica Trobec Zadnik   +1 more
doaj   +1 more source

Using miRNA-Analyzer for the Analysis of miRNA Data [PDF]

open access: yesMicroarrays, 2016
MicroRNAs (miRNAs) are small biological molecules that play an important role during the mechanisms of protein formation. Recent findings have demonstrated that they act as both positive and negative regulators of protein formation. Thus, the investigation of miRNAs, i.e., the determination of their level of expression, has developed a huge interest in
Pietro Guzzi   +2 more
openaire   +2 more sources

Identification of candidate miRNA biomarkers for facioscapulohumeral muscular dystrophy using DUX4-based mouse models

open access: yesDisease Models & Mechanisms, 2021
Facioscapulohumeral muscular dystrophy (FSHD) is caused by misexpression of DUX4 in skeletal myocytes. As DUX4 is the key therapeutic target in FSHD, surrogate biomarkers of DUX4 expression in skeletal muscle are critically needed for clinical trials ...
Andreia M. Nunes   +3 more
doaj   +1 more source

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