Results 11 to 20 of about 367,525 (161)

Glutathione imparts stress tolerance against Alternaria brassicicola infection via miRNA mediated gene regulation

Plant Signaling & Behavior, 2022
Glutathione (GSH) is well known to play a crucial role in imparting resistance against various pathogen invasions. Nevertheless, the role of GSH in regulating miRNA-mediated defense response is yet to be explored.
Riddhi Datta, Kajal Mandal, Priyanka Boro, Asma Sultana, Sharmila Chattopadhyay   +4 more
doaj   +1 more source

Astrocyte deletion of Bmal1 alters daily locomotor activity and cognitive functions via GABA signalling

Nature Communications, 2017
Core clock genes, such asBmal1, are expressed in astrocytes, but their contribution to the timekeeping system is unknown. Barca-Mayo et al. report that deletion of Bmal1in Glast+ astrocytes alters the neuronal clock through GABA signalling, leading to ...
Olga Barca-Mayo, Meritxell Pons-Espinal, Philipp Follert, Andrea Armirotti, Luca Berdondini, Davide De Pietri Tonelli   +5 more
doaj   +1 more source

The impact of plasmid on regeneration and expression efficiencies of gfp gene in tobacco (Nicotiana tabacum L.)

Acta Agriculturae Slovenica, 2014
Tobacco leaf explants were transformed by bacteria Agrobacterium tumefaciens (A. t.) and plasmid pBIN mgfp5-ER, which has a single copy of the green fluorescent gfp gene and A. t.-pART27 2mgfp5-ER, which has two copies of the gfp gene. Both plasmids have
Niko PAVLIN, Zlata LUTHAR
doaj   +1 more source

MiRNA-21 in osteoblastogenes.

, 2023
BackgroundMany researchers focused on diverse miRNAs in the progression of osteoporosis in postmenopausal women. This study aimed to evaluate the association between plasma miRNA-21-5p and miRNA-422a with osteoporosis in postmenopausal women.MethodsThis ...
Alireza Ostadrahimi (8951063), Azizeh Farshbaf-khalili (17200002), Neda Mohammadisima (17199999)   +2 more
core   +1 more source

DGCR8 Promotes Neural Progenitor Expansion and Represses Neurogenesis in the Mouse Embryonic Neocortex

Frontiers in Neuroscience, 2018
DGCR8 and DROSHA are the minimal functional core of the Microprocessor complex essential for biogenesis of canonical microRNAs and for the processing of other RNAs. Conditional deletion of Dgcr8 and Drosha in the murine telencephalon indicated that these
Nadin Hoffmann, Stefan C. Weise, Federica Marinaro, Tanja Vogel, Davide De Pietri Tonelli   +4 more
doaj   +1 more source

Dissimilar Appearances Are Deceptive–Common microRNAs and Therapeutic Strategies in Liver Cancer and Melanoma

Cells, 2020
In this review, we summarize the current knowledge on miRNAs as therapeutic targets in two cancer types that were frequently described to be driven by miRNAs—melanoma and hepatocellular carcinoma (HCC).
Lisa Linck-Paulus, Claus Hellerbrand, Anja K. Bosserhoff, Peter Dietrich   +3 more
doaj   +1 more source

In silico miRNA prediction in metazoan genomes: balancing between sensitivity and specificity [PDF]

, 2009
Background MicroRNAs (miRNAs), short ~21-nucleotide RNA molecules, play an important role in post-transcriptional regulation of gene expression. The number of known miRNA hairpins registered in the miRBase database is rapidly increasing, but recent ...
Roeland CHJ van Ham, Ham, R.C.H.J., van, van der Burgt, A., Ate van der Burgt, Jan-Peter Nap, Mark WJE Fiers, van Ham Roeland CHJ, Fiers Mark WJE, Nap Jan-Peter, van der Burgt Ate, Burgt, A., van der, Fiers, M.W.E.J., Nap, J.P.H., van Ham, R.C.H.J.   +13 more
core   +1 more source

MiRNA-21 in osteoclastogenes.

, 2023
BackgroundMany researchers focused on diverse miRNAs in the progression of osteoporosis in postmenopausal women. This study aimed to evaluate the association between plasma miRNA-21-5p and miRNA-422a with osteoporosis in postmenopausal women.MethodsThis ...
Alireza Ostadrahimi (8951063), Azizeh Farshbaf-khalili (17200002), Neda Mohammadisima (17199999)   +2 more
core   +1 more source

miREE: miRNA Recognition Elements Ensemble [PDF]

, 2011
Background Computational methods for microRNA target prediction are a fundamental step to understand the miRNA role in gene regulation, a key process in molecular biology. In this paper we present miREE, a novel microRNA target prediction tool.
Enrico Macii, Acquaviva, Andrea, Paula H Reyes-Herrera, Macii Enrico, Acquaviva Andrea, REYES HERRERA, PAULA HELENA, Andrea Acquaviva, Elisa Ficarra, Ficarra, Elisa, Reyes-Herrera Paula H, Macii, Enrico, Ficarra Elisa, Reyes Herrera Ph   +12 more
core   +1 more source

The importance of training in contemporary organizations

Mенаџмент у хотелијерству и туризму, 2019
This paper describes the concepts of training and career development for employees, level of knowledge of workers, the profit that some companies had from continuous training, and the way in which an organizational psychologist, with the support of ...
Ana Slavković, Vukan Slavković
doaj   +1 more source