Results 31 to 40 of about 466,733 (303)
Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms, 2011 Adenovirus infection has a tremendous impact on the cellular silencing machinery. Adenoviruses express high amounts of non-coding virus associated (VA) RNAs able to saturate key factors of the RNA interference (RNAi) processing pathway, such as Exportin 5 and Dicer. Furthermore, a proportion of VA RNAs is cleaved by Dicer into viral microRNAs (mivaRNAs)
Carnero, Elena +2 more
openaire +2 more sources
ŽUPANČIČEVA ZAPUŠČINA IN NJEGOVA OSEBNA KNJIŽNICA
Knjižnica, 2015 Zapuščina književnika Otona Župančiča, ki jo je Mestnemu muzeju Ljubljana leta 1985 z darilno pogodbo izročila umetnikova družina, sodi med redke tako obsežne in raznovrstne umetniške zapuščine.
Dragica Trobec Zadnik +1 more
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MicroRNA-6744-5p promotes anoikis in breast cancer and directly targets NAT1 enzyme
Cancer Biology & Medicine, 2020 Objective: Anoikis is apoptosis that is induced when cells detach from the extracellular matrix and neighboring cells. As anoikis serves as a regulatory barrier, cancer cells often acquire resistance towards anoikis during tumorigenesis to become ...
Sharan Malagobadan +2 more
doaj +1 more source
Epigenetics, 2022 Exposure to metals increases risk for pregnancy complications. Extracellular vesicle (EV) miRNA contribute to maternal-foetal communication and are dysregulated in pregnancy complications.
Caitlin G. Howe +8 more
doaj +1 more source
Retrograde trafficking of Argonaute 2 acts as a rate-limiting step for de novo miRNP formation on endoplasmic reticulum–attached polysomes in mammalian cells [PDF]
, 2020 microRNAs are short regulatory RNAs in metazoan cells. Regulation of miRNA activity and abundance is evident in human cells where availability of target messages can influence miRNA biogenesis by augmenting the Dicer1-dependent processing of precursors ...
Barman, Bahnisikha +4 more
core
miRNA contributions to pediatric-onset multiple sclerosis inferred from GWAS. [PDF]
, 2019 ObjectiveOnset of multiple sclerosis (MS) occurs in childhood for approximately 5% of cases (pediatric MS, or ped-MS). Epigenetic influences are strongly implicated in MS pathogenesis in adults, including the contribution from microRNAs (miRNAs), small ...
Aaen, Gregory +31 more
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BMC Medical Research Methodology, 2019 Background Reporting quality of systematic reviews’ (SRs) abstracts is important because this is often the only information about a study that readers have. The aim of this study was to assess adherence of SR abstracts in the field of anesthesiology with
Katarina Maticic +2 more
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Primary cutaneous anaplastic large cell lymphoma shows a distinct miRNA expression profile and reveals differences from tumor-stage mycosis fungoides [PDF]
, 2012 Copyright @ 2012 John Wiley & SonsThe miRNA expression profiles of skin biopsies from 14 primary cutaneous anaplastic large cell lymphoma (C-ALCL) patients were analysed with miRNA microarrays using the same control group of 12 benign inflammatory ...
Ballabio, E +7 more
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Disease Models & Mechanisms, 2021 Facioscapulohumeral muscular dystrophy (FSHD) is caused by misexpression of DUX4 in skeletal myocytes. As DUX4 is the key therapeutic target in FSHD, surrogate biomarkers of DUX4 expression in skeletal muscle are critically needed for clinical trials ...
Andreia M. Nunes +3 more
doaj +1 more source
The ribosomal protein RACK1 is required for microRNA function in both C. elegans and humans [PDF]
, 2011 Despite the importance of microRNAs (miRNAs) in gene regulation, it is unclear how the miRNA-Argonaute complex-or miRNA-induced silencing complex (miRISC)-can regulate the translation of their targets in such diverse ways.
Bajan, Sarah +7 more
core +3 more sources