Results 61 to 70 of about 340,419 (317)

Expressions and clinic significance of miRNA-143, miRNA- 34A, miRNA-944, miRNA-101 and miRNA-218 in cervical cancer tissues

open access: yesTropical Journal of Pharmaceutical Research, 2016
Purpose: To search for novel biomarkers for early diagnosis of cervical cancer, as well as novel therapeutic target for cervical cancer.Methods: A total of 96 cervical tissue specimens were collected from patients in the Second Affiliated Hospital of Zhengzhou University, out of which 10 were normal control.
Wang, Feng   +4 more
openaire   +3 more sources

Full - transcriptome analysis of miRNA expression in mononuclear cells in patients with acute decompensation of chronic heart failure of various etiologies [PDF]

open access: yesТерапевтический архив, 2019
It is known that micro RNAs are an important regulatory element in the pathogenesis of many diseases, including cardiovascular diseases. Different levels of expression of these molecules in various pathologies makes miRNA a potential diagnostic and ...
I V Zhirov   +7 more
doaj   +1 more source

miRNA-seq - Differential Expression Analysis

open access: yes, 2016
miRNA-seq differential expression analysis ...
Ahmet Sinan Yavuz (633993)
core   +1 more source

MiR‐513a promotes human erythroid differentiation by modulating c‐Jun

open access: yesFEBS Open Bio, EarlyView.
During early human erythropoiesis, miR‐513a promoted erythroid differentiation in primary human CD34+ hematopoietic stem‐progenitor cells and human TF‐1 erythroleukemic cells by indirectly decreasing c‐Jun and phospho‐c‐Jun expression, which are associated with increased GATA1 expression.
MinJung Kim   +11 more
wiley   +1 more source

CircRNA-miRNA-hubgene network.

open access: yes, 2019
The network consists of 10 circRNAs, 5 miRNAs, and 10 hub_genes. Vs indicate circRNAs, diamonds indicate miRNA, and round rectangles indicate mRNA.
Wei-dong Jiang (7114763)   +1 more
core   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

open access: yesFEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji   +2 more
wiley   +1 more source

miRNAs: Whys and Wherefores of miRNA-Mediated Regulation [PDF]

open access: yesCurrent Biology, 2005
MiRNAs are assumed to be important in animal development and physiology, but their specific roles in vivo are still poorly understood. New bioinformatic and genetic studies are setting the stage for unraveling the specific biological functions of miRNAs.
openaire   +2 more sources

Investigation of miRNA Functionality in Cystic Fibrosis

open access: yesمجله دانشکده پزشکی اصفهان, 2019
Cystic fibrosis (CF) is an autosomal recessive disorder caused by mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene. The irregularities in miRNA expression have been reported in many pulmonary diseases, including CF.
Maryam Hassanzad   +3 more
doaj   +1 more source

Emerging insights into CC and CXC chemokines and their receptors in Mycobacterium tuberculosis infection

open access: yesFEBS Open Bio, EarlyView.
The dual roles of CC and CXC chemokines in distinguishing active, latent, and subclinical tuberculosis were reviewed, along with an evaluation of their potential as diagnostic biomarkers and therapeutic targets to advance precision medicine in tuberculosis management. The graphical abstract was generated with AI assistance (Gemini 3.0).
Xuying Yin, Dangsheng Xiao, Jiezuan Yang
wiley   +1 more source

Associations of miRNA-146a and miRNA-223 with Rheumatoid Arthritis and Their Predictive Values

open access: yes, 2023
Haoshaqiang Zhang,1,* Hua Shang,1,2,* Zhigang Wang,1 Kun Li1 1Department of Orthopedics Surgery, People’s Hospital of Xinjiang Uygur Autonomous Region, Urumqi, People’s Republic of China; 2Department of Human Resources, People’s Hospital of ...
Zhang H, Shang H, Li K, Wang Z
core  

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