Results 81 to 90 of about 340,419 (317)

Extracellular vesicle microRNA in early versus late pregnancy with birth outcomes in the MADRES study

Epigenetics, 2022
Circulating miRNA may contribute to the development of adverse birth outcomes. However, few studies have investigated extracellular vesicle (EV) miRNA, which play important roles in intercellular communication, or compared miRNA at multiple time points ...
Caitlin G Howe, Helen B Foley, Elizabeth M Kennedy, Sandrah P Eckel, Thomas a Chavez, Dema Faham, Brendan H Grubbs, Laila Al-Marayati, Deborah Lerner, Shakira Suglia, Theresa M Bastain, Carmen J Marsit, Carrie V Breton   +12 more
doaj   +1 more source

miRNA

miRNA ...
Luca Bianco (18332010), Fontana (18331971), Luisa Palmieri (18332488)   +2 more
core   +1 more source

Image6_Integrated Analysis of Angiogenesis Related lncRNA-miRNA-mRNA in Patients With Coronary Chronic Total Occlusion Disease.PNG

, 2022
Background: Coronary chronic total occlusion (CTO) disease is common and its specific characteristic is collateral formation. The Integrated analysis of angiogenesis related lncRNA-miRNA-mRNA network remains unclear and might provide target for future ...
Wei Gao (2085), Jie Yuan (208425), Junbo Ge (385426), Runda Wu (11464579), Jianhui Zhang (450305)   +4 more
core   +1 more source

Aptamer‐Based Delivery Systems for VEGF and NGF Modulation in Ocular Therapies

Advanced Healthcare Materials, EarlyView.
Aptamer‐based delivery systems targeting NGF and VEGF hold significant potential for precise and sustained treatment of complex diseases affecting both the anterior and posterior segments of the eye. This review critically summarizes current strategies for NGF and VEGF delivery as well as VEGF sequestration, providing a clinical perspective on how ...
Nadine Best, Gizem Karabiyik, Gerd Geerling, Sarah Barbara Zwingelberg, Gregor Lang, Martin Humenik   +5 more
wiley   +1 more source

The ribosomal protein RACK1 is required for microRNA function in both C. elegans and humans [PDF]

, 2011
Despite the importance of microRNAs (miRNAs) in gene regulation, it is unclear how the miRNA-Argonaute complex-or miRNA-induced silencing complex (miRISC)-can regulate the translation of their targets in such diverse ways.
Gyorgy Hutvagner, Guillaume Jannot, Samir Bouasker, Giguère, Nellie J., Bajan, Sarah, Simard, Martin J., Banville, Isabelle H., Giguère, NJ, Sandra Piquet, Jannot, Guillaume, Bouasker, S, Hutvagner, Gyorgy, Banville, IH, Nellie J Giguère, Bajan, S, Martin J Simard, Piquet, Sandra, Hutvagner, G, Simard, MJ, Bouasker, Samir, Jannot, G, Piquet, S, Sarah Bajan, Isabelle H Banville   +23 more
core   +1 more source

Extracellular Vesicles Modulation by an Adiponectin Receptor Agonist Provides Cardioprotection for Myocardial Ischemic Injury

Advanced Healthcare Materials, EarlyView.
This study demonstrates that ALY688, a drug mimicking the heart‐protective hormone adiponectin, reduces myocardial ischemia injury. ALY688 increases the production of extracellular vesicles, which carry protective cargo including adiponectin itself.
Jialing Tang, Wing Yan Chung, Serena M. Pulente, Yubin Lei, Khang Nguyen, Eddie Tam, Nadya M. Morrow, Ilka Lorenzen‐Schmidt, Fengxia Xiao, Augusto Zani, Dylan Burger, Hye Kyoung Sung, Erin E. Mulvihill, Gary Sweeney   +13 more
wiley   +1 more source

Profiling of miRNAs in pediatric asthma: Upregulation of miRNA-221 and miRNA-485-3p

Molecular Medicine Reports, 2012
The aim of this study was to investigate the expression profiles of microRNAs (miRNAs) in pediatric asthma and to determine candidate miRNAs responsible for the pathogenesis of this disease. Microarrays were used to detect the differences in the miRNA expression levels between asthmatic children and controls. Airway
Feng, Liu, Hou-Bing, Qin, Bing, Xu, Hui, Zhou, De-Yu, Zhao   +4 more
openaire   +3 more sources

Insights into Novel Infant Milk Formula Bioactives

Nutrition and Dietary Supplements, 2020
Jordan Skolnick,1 Claire Chou,1 John Miklavcic1,2 1Schmid College of Science and Technology, Chapman University, Orange, CA 92866, USA; 2School of Pharmacy, Chapman University, Irvine, CA 92618, USACorrespondence: John MiklavcicSchmid College of Science ...
Skolnick J, Chou C, Miklavcic J
doaj  

Image5_Integrated Analysis of Angiogenesis Related lncRNA-miRNA-mRNA in Patients With Coronary Chronic Total Occlusion Disease.PNG

, 2022
Background: Coronary chronic total occlusion (CTO) disease is common and its specific characteristic is collateral formation. The Integrated analysis of angiogenesis related lncRNA-miRNA-mRNA network remains unclear and might provide target for future ...
Wei Gao (2085), Jie Yuan (208425), Junbo Ge (385426), Runda Wu (11464579), Jianhui Zhang (450305)   +4 more
core   +1 more source

Hierarchically Engineered Multi‐Enzyme Nanoreactors for in vitro Drug Biosynthesis and Pathway Transplantation Into Cells

Advanced Materials, EarlyView.
A hierarchically structured metal–organic framework (eMIL) is shown to host the complete six‐enzyme biosynthesis pathway for the anti‐cancer pigment violacein, reshaping reaction dynamics and multiplying in vitro yields. eMIL nanoreactors deliver this reconstituted bacterial multi‐protein system into mammalian cells, where cell‐derived substrates and ...
Ainur Sharip, Somayah S. Qutub, Manar M. Farooqui, Walaa Baslyman, Nida Khalfay, Lukman O. Alimi, Patricia Lopez Sanchez, Lingyun Zhao, Milena Chernyshevskaia, Giovanni Colombo, Niveen M. Khashab, Stefan T. Arold, Raik Grünberg   +12 more
wiley   +1 more source