Results 101 to 110 of about 340,419 (317)
LncRNA A1BG-AS1 regulates the progress of diabetic foot ulcers via sponging miR-214-3p
Endocrine JournalNerve aberrations and vascular lesions in the distal lower limbs are the etiological factors for diabetic foot ulcers (DFUs). This study aimed to understand the regulatory mechanism of angiogenesis in patients with DFU by examining lncRNA, as well as to ...
Fangfang Wu +3 more
doaj +1 more source
Investigating the association of rs1951032 Polymorphism in the pre-miR-487a flanking region with incidence of breast cancer in Iranian women [PDF]
Journal of Advanced Biomedical Sciences, 2017 Background & Objective: MiRNAs are among non-coding RNAs involved in regulation of the target genes through a direct interaction with the mRNA. Therefore, any variation in the miRNA genes could be effective in modification of the functionality of miRNA ...
Reza Hashemi, Maryam Peymani
doaj
Profound effect of profiling platform and normalization strategy on detection of differentially expressed microRNAs [PDF]
, 2012 Adequate normalization minimizes the effects of systematic technical variations and is a prerequisite for getting meaningful biological changes. However, there is inconsistency about miRNA normalization performances and recommendations.
Wagner, Carola +4 more
core +1 more source
, 2022 Background: Coronary chronic total occlusion (CTO) disease is common and its specific characteristic is collateral formation. The Integrated analysis of angiogenesis related lncRNA-miRNA-mRNA network remains unclear and might provide target for future ...
Wei Gao (2085) +4 more
core +1 more source
Advanced Science, EarlyView.TRMT6‐mediated m1A modification in CDK9 mRNA enhances its mRNA stability and translation efficiency, thereby increasing the protein levels of CDK9. Upregulated CDK9 promotes the progression of HCC by elevating the levels of oncogenic factors including p‐STAT3, MCL1, and BCL‐2. On the other hand, CDK9 phosphorylates TARDBP at Ser254 to activate HBV core
Rui Zhang +12 more
wiley +1 more source
Functional analysis of miRNA regulated genes in prostate cancer as potential diagnostic molecules [PDF]
, 2016 >Magister Scientiae - MScProstate Cancer is the leading cause of cancer-related death in males in the Western world. It is a common biological disease originating from the reproductive system of the male namely, the prostate gland, usually in older ...
Abdullah, Gadija
core +1 more source
The role of miRNAs as biomarkers in heterotopic ossification
EFORT Open ReviewsFibrodysplasia ossificans progressiva and progressive osseous heteroplasia are genetic forms of heterotopic ossification (HO). Fibrodysplasia ossificans progressiva is caused by ACVR1 gene mutations, while progressive osseous heteroplasia is caused by ...
Chen Xie +5 more
doaj +1 more source
Journal of Inflammation Research, 2022 Cheng-Shyuan Rau1 *, Pao-Jen Kuo2 *, Hui-Ping Lin,2 Chia-Jung Wu,2 Yi-Chan Wu,2 Peng-Chen Chien,2 Ting-Min Hsieh,3 Hang-Tsung Liu,3 Chun-Ying Huang,3 Ching-Hua Hsieh2 1Department of Neurosurgery, Kaohsiung Chang Gung Memorial Hospital and Chang ...
Rau CS +9 more
doaj
, 2022 Background: Coronary chronic total occlusion (CTO) disease is common and its specific characteristic is collateral formation. The Integrated analysis of angiogenesis related lncRNA-miRNA-mRNA network remains unclear and might provide target for future ...
Wei Gao (2085) +4 more
core +1 more source
Paternal Circadian Disruption Impairs Offspring Cognition via Sperm microRNAs
Advanced Science, EarlyView.Paternal circadian disruption remodels the sperm small RNA payload, elevating miR‐92a‐3p/miR‐25‐3p levels and perturbing early embryonic gene regulatory programs. Microinjection experiments and single‐embryo transcriptomics reveal sex‐specific developmental vulnerabilities, ultimately impairing offspring hippocampal synaptic plasticity and cognition ...
Kexin Zou +22 more
wiley +1 more source