Results 11 to 20 of about 294,358 (306)
MicroRNA-34, microRNA-130, microRNA-148, microRNA-181, microRNA-194 and microRNA-605 expression in colon cancer tissue [PDF]
Южно-Российский онкологический журналPurpose of the study. Determination of the expression of microRNA‑34, microRNA‑130, microRNA‑148, microRNA‑181, microRNA‑194 and microRNA‑605 in colon tumor tissue depending on the clinical and morphological features of the tumor and the effectiveness of
D. I. Azovsky +6 more
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MMpred: functional miRNA – mRNA interaction analyses by miRNA expression prediction [PDF]
, 2012 Background: MicroRNA (miRNA) directed gene repression is an important mechanism of posttranscriptional regulation. Comprehensive analyses of how microRNA influence biological processes requires paired miRNA-mRNA expression datasets.
Wilson, Paul +2 more
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Secreted miRNAs in the tripartite neuromuscular junction [PDF]
ExRNA, 2019 microRNAs are small, non-coding, single-stranded RNAs that can suppress mRNA translation at the posttranscriptional level by binding to imperfect complementary sequences on mRNA targets and then cause their degradation or hinder protein translation ...
Liangsheng Lu +6 more
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Journal of Allergy and Clinical Immunology, 2018 MicroRNAs (miRNAs) are small endogenous RNAs that regulate gene-expression posttranscriptionally. MiRNA research in allergy is expanding because miRNAs are crucial regulators of gene expression and promising candidates for biomarker development.
Thomas X. Lu, Marc E. Rothenberg
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Initial function of microRNAs as a defence mechanism against invading organisms [PDF]
ExRNA, 2019 Background: Although microRNA (miRNA) regulation is widely considered as a mechanism to regulate gene expression in metazoans, plants and viruses, there are recent reports that show the interaction between viruses and their mammal hosts via miRNAs ...
Xiaoshuang Liu +5 more
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Stem Cell Research & Therapy, 2022 Background Anti-inflammatory polarized macrophages are reported to alleviate systemic lupus erythematosus (SLE). Our previous studies have demonstrated that exosomes from adipose-derived stem cells promote the anti-inflammatory polarization of ...
Mingchao Zhang +8 more
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Nature Communications, 2023 Renal tubular atrophy is a hallmark of chronic kidney disease. The study by Zhu et al. reveals the protective role of tubular polynucleotide phosphorylase (PNPT1) against renal atrophy by blocking the leakage of mitochondrial dsRNAs into cytoplasm where ...
Yujie Zhu +12 more
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Tumor-specific delivery of KRAS siRNA with iRGD-exosomes efficiently inhibits tumor growth [PDF]
ExRNA, 2019 Lung cancer is the major cause of cancer-related deaths globally. Mutant KRAS is a feature of 15–50% of lung cancer cases and represents one of the most prevalent oncogenic drivers in this disease.
Yu Zhou +5 more
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MicroRNA: MicroRNAs Reach out into Dendrites [PDF]
Current Biology, 2006 A recent study has shown that miR-134, a brain-specific microRNA, is present in dendrites where it represses the local synthesis of the protein kinase LimK1; this is a novel form of translational regulation in dendrites and may have important physiological implications.
Tai, H., Schuman, E.
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In vivo self-assembled siRNA as a modality for combination therapy of ulcerative colitis
Nature Communications, 2022 Management of ulcerative colitis can require a combination of treatments targeting different pathways. Here the authors design a therapy for ulcerative colitis based on a multitargeted genetic circuit to simultaneously target TNF-α, B7-1 and integrin α4,
Xinyan Zhou +10 more
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