Results 21 to 30 of about 505,053 (355)

Viral MicroRNA Effects on Pathogenesis of Polyomavirus SV40 Infections in Syrian Golden Hamsters [PDF]

open access: yes, 2014
Shaojie Zhang, Vojtech Sroller, Preeti Zanwar, Steven J. Halvorson, Nadim J. Ajami, Corey W. Hecksel, Jody L. Swain, Connie Wong, Janet S. Butel, Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, Texas, United States
Ajami, Nadim J.   +10 more
core   +3 more sources

microRNA Bioinformatics

open access: yesCells, 2022
Firstly, I apologize for the delayed publication of this Special Issue in the form of a book title [...]
openaire   +3 more sources

Serum microRNA Profiles Serve as Novel Biomarkers for Autoimmune Diseases

open access: yesFrontiers in Immunology, 2018
Autoimmune diseases involve a complex dysregulation of immunity. Autoimmune diseases include many members [e.g., rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE)], and most of them are classified according to what organs and tissues are ...
Fangfang Jin   +6 more
doaj   +1 more source

YTHDF1 mitigates acute kidney injury via safeguarding m6A-methylated mRNAs in stress granules of renal tubules

open access: yesRedox Biology, 2023
Acute kidney injury (AKI) presents a daunting challenge with limited therapeutic options. To explore the contribution of N6-methyladenosine (m6A) in AKI development, we have investigated m6A-modified mRNAs within renal tubular cells subjected to injuries
Wenwen Yang   +8 more
doaj   +1 more source

MicroRNAs in the stressed heart: Sorting the signal from the noise [PDF]

open access: yes, 2014
The short noncoding RNAs, known as microRNAs, are of undisputed importance in cellular signaling during differentiation and development, and during adaptive and maladaptive responses of adult tissues, including those that comprise the heart.
Matkovich, Scot J
core   +3 more sources

The miR-125a/HK2 axis regulates cancer cell energy metabolism reprogramming in hepatocellular carcinoma

open access: yesScientific Reports, 2017
The Warburg effect is a metabolic hallmark of cancer. Tumor cells rapidly adjust their energy source to glycolysis in order to efficiently proliferate in a hypoxic environment, but the mechanism underlying this switch remains incompletely understood ...
Fangfang Jin   +8 more
doaj   +1 more source

Serum microRNA array analysis identifies miR-140-3p, miR-33b-3p and miR-671-3p as potential osteoarthritis biomarkers involved in metabolic processes. [PDF]

open access: yes, 2017
Background: MicroRNAs (miRNAs) in circulation have emerged as promising biomarkers. In this study, we aimed to identify a circulating miRNA signature for osteoarthritis (OA) patients and in combination with bioinformatics analysis to evaluate the utility
A Brazma   +59 more
core   +2 more sources

Pyruvate kinase type M2 promotes tumour cell exosome release via phosphorylating synaptosome-associated protein 23

open access: yesNature Communications, 2017
Exosomes, vesicles secreted by cancer cells, have a role in cancer progression but the mechanisms regulating their biogenesis are mostly unknown. Here the authors show that PKM2, a rate-limiting glycolytic enzyme overexpressed in cancer cells, mediates ...
Yao Wei   +14 more
doaj   +1 more source

Biogenesis and function of extracellular miRNAs

open access: yesExRNA, 2019
Mature microRNAs (miRNAs) are 18–24-nucleotide non-coding RNAs with post-transcriptional regulatory functions and have been documented as an essential cornerstone of the genetic system.
Chihao Zhao, Xinlei Sun, Limin Li
doaj   +1 more source

Regulation of brain endothelial barrier function by microRNAs in health and neuroinflammation [PDF]

open access: yes, 2016
Brain endothelial cells constitute the major cellular element of the highly specialized blood–brain barrier (BBB) and thereby contribute to CNS homeostasis by restricting entry of circulating leukocytes and blood-borne molecules into the CNS.
Arie Reijerkerk   +6 more
core   +3 more sources

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