Results 11 to 20 of about 1,367 (104)

Comparative analysis of 2‐year outcomes in GRIT and TRUFFLE trials

Ultrasound in Obstetrics &Gynecology, Volume 55, Issue 1, Page 68-74, January 2020., 2020
ABSTRACT Objective To explore the effect on perinatal outcome of different fetal monitoring strategies for early‐onset fetal growth restriction (FGR). Methods This was a cohort analysis of individual participant data from two European multicenter trials of fetal monitoring methods for FGR: the Growth Restriction Intervention Study (GRIT) and the Trial ...
W. Ganzevoort, J. G. Thornton, N. Marlow, B. Thilaganathan, B. Arabin, F. Prefumo, C. Lees, H. Wolf, for the GRIT Study Group, the TRUFFLE Study Group, B Van Bulck, G M Kalakoutis, P Sak, K T M Schneider, S E Karpathios, T Major, T Todros, D Arduini, C Flumini, A C Tenore, N Roncaglia, T Frusca, G Ferretti, M J N Weinans, J van Roosmalen, J W van der Slikke, H van Geijn, P J M Pernet, H Wolf, R H Stigter, J Wilczynski, E Vasco, M Abdullah, Z Novak‐Antolic, P Danielian, S D Jenkinson, C R Welch, C Griffin, H Gee, D Tuffnell, J Cresswell, T Tariq, B Sengupta, G Tydeman, D Churchill, S Bewley, L Fusi, S W Lindow, W Johal, F M Fairlie, K Neales, G Mason, I Scudamore, J Konje, S A Walkinshaw, M Griffiths, A Dawson, G Mires, R Johanson, R B Fraser, P Hendy Ibbs, S A Steel, M Ramsay, J B Robins, M J Heard, H M Tonge, I T Manyonda, J Walker, M Maresh, A Yoong, P Soothill, H Cameron, D Byrne, B Beattie, S Bober, M Van Damme, S Kyriakides, P Pokorna, A Zimmerman, H Tsitsikas, E Mani, P Bosisio, E Mastritta, M Nicocia, C Fabris, P Eken, L De Vries, Z Kubicka, R Ramalho, M Rashid, L Cerar‐Kornhauser, S Thomas, A Elliman, T Sim, S Swaminathan, L Walker, D McCormick, Z Sibanda, J Hughes, J Kilding, A O'Hara, V Harpin, N Porter, S Pandey, K Murtagh, K Burton, R MacGregor, B Stewart, H Klenke, P Hallam, N Kai, M Graham, A Harrison, E Saharia, T McGhee, P Rowsell, P Howie, Max Parmar, D Field, A Grant, P Steer, G Breart, M Levene, D Torgeson, S Kitzinger, M Levene, N Marlowe, D Wolke, L De Vries, A Johnson, G Ferretti, Birgit Arabin, Caterina M Bilardo, Christoph Brezinka, Jerome M J Cornette, Jan B Derks, Anke Diemert, Johannes J Duvekot, Enrico Ferrazzi, Nicola Fratelli, Tiziana Frusca, Wessel Ganzevoort, Kurt Hecher, Aleid van Leemhuis, Christoph C Lees, Silvia Lobmaier, Neil Marlow, Pasquale Martinelli, Gianpaolo Maso, Hannah Missfelder‐Lobos, Raffaele Napolitano, Eva Ostermayer, Aris T Papageorghiou, Federico Prefumo, Dietmar Schlembach, K T M Schneider, Baskaran Thilaganathan, Tullia Todros, Adriana Valcamonico, Gerard H A Visser, Hans Wolf, John Kingdom, Karel Marsal, Jim Thornton, Herbert Valensise   +164 more
wiley   +1 more source

Outcome of monochorionic diamniotic twin pregnancy with selective fetal growth restriction and continuous or intermittent absent or reversed end‐diastolic umbilical artery flow: international multicenter cohort study

Ultrasound in Obstetrics &Gynecology, Volume 66, Issue 1, Page 41-50, July 2025.
ABSTRACT Objectives Monochorionic diamniotic (MCDA) twins with selective fetal growth restriction (sFGR) and either continuous (cAREDF) or intermittent (iAREDF) absent or reversed end‐diastolic flow in the umbilical artery face significant fetal and neonatal risks.
A. T. R. Noll, A. van Hoogstraten, K. Nulens, N. van Geloven, T. Van Mieghem, S. Shinar, P. A. Zuazagoitia, M. Bennasar, F. M. Russo, E. Tiblad, L. Herling, L. Lewi, E. J. T. (Joanne) Verweij, on behalf of the ALIGN Study Group, Femke Slaghekke, Monique C Haak, Enrico Lopriore, Lotte E van der Meeren, Johannes van der Merwe, Roland Devlieger   +19 more
wiley   +1 more source

Placental biomarker and fetoplacental Doppler abnormalities are strongly associated with placental pathology in pregnancies with small‐for‐gestational‐age fetus: prospective study

Ultrasound in Obstetrics &Gynecology, Volume 65, Issue 6, Page 749-760, June 2025.
ABSTRACT Objective Placental dysfunction can result in small‐for‐gestational age (SGA) or fetal growth restriction (FGR). The aim of this prospective cohort study was to assess the association of the cerebroplacental ratio (CPR) and other more conventional fetoplacental Doppler indices, circulating placental growth factor (PlGF) levels and soluble fms ...
J. Hong, K. Crawford, E. Cavanagh, V. Clifton, F. da Silva Costa, A. V. Perkins, S. Kumar   +6 more
wiley   +1 more source

Prenatal diagnosis and postnatal outcome of Type‐III vasa previa: systematic review of literature

Ultrasound in Obstetrics &Gynecology, Volume 63, Issue 1, Page 24-33, January 2024.
ABSTRACT Objective Type‐III vasa previa (VP) is a rare form of VP, not necessarily associated with other placental or vascular anomalies, in which aberrant vessels run from the placenta to the amniotic membranes, near the internal cervical os, before returning to the placenta. Early diagnosis of Type‐III VP is important but technically challenging. The
M. Pozzoni, C. Sammaria, R. Villanacci, C. Borgese, F. Ghisleri, A. Farina, M. Candiani, P. I. Cavoretto   +7 more
wiley   +1 more source

抗原诱导的人脐血CTL细胞活性的实验研究

Zhongguo shiyan zhenduanxue, 2008
目的因脐血干细胞增殖能力自我更新能力较强,故脐血造血干细胞生物学特性研究已经成为热点。本文探讨观察了所提抗原及其对人脐血细胞（CTL）诱导的特异性抗肿瘤作用。方法用密度梯度离心法提取人肿瘤抗原,并测定诱导的人脐血细胞CTL活性。结果小肠纤维肉瘤Ag诱导4天后,不同效价实验组CTL活性均有升高,效价1∶100的抗原诱导的CTL活性最强。乳腺癌抗原诱导8天后,效价1∶100实验组CTL活性显著提高,结论所提两种抗原效果良好,可明显诱导脐血CTL活性,以效价1∶100实验组最佳。
张健, 赵珍谊, 陈阳, 石虹, 任林广, 夏风琴   +5 more
doaj  

IL-2,TNFα激活的脐血单核细胞对K562细胞株杀伤作用的研究

Zhongguo shiyan zhenduanxue, 2003
目的　评价IL - 2 ,TNFα ,IL - 2联合TNFα激活的脐血单核细胞 （Mφ）对白血病细胞株K5 6 2的细胞毒作用。方法　将IL - 2 ,TNFα ,IL - 2联合TNFα分别激活的脐血单核细胞按效靶比 2 0 :1,5 0 :1加入白血病细胞株K5 6 2共同培养 4 8小时 ,采用MTT法检测各组的细胞毒效应。结果　IL - 2 ,TNFα分别激活的脐血单核细胞对白血病细胞株K5 6 2有杀伤作用 ,但较弱 ,而将IL - 2联合TNFα激活的单核细胞对其杀伤作用明显增强 ...
王晓波, 高强, 宋振岚
doaj  

IL-2,TNFα激活的脐血单核细胞对K562细胞株杀伤作用的研究 附视频

Zhongguo shiyan zhenduanxue, 2003
目的　评价IL - 2 ,TNFα ,IL - 2联合TNFα激活的脐血单核细胞 (Mφ)对白血病细胞株K5 6 2的细胞毒作用。方法　将IL - 2 ,TNFα ,IL - 2联合TNFα分别激活的脐血单核细胞按效靶比 2 0 :1,5 0 :1加入白血病细胞株K5 6 2共同培养 4 8小时 ,采用MTT法检测各组的细胞毒效应。结果　IL - 2 ,TNFα分别激活的脐血单核细胞对白血病细胞株K5 6 2有杀伤作用 ,但较弱 ,而将IL - 2联合TNFα激活的单核细胞对其杀伤作用明显增强 ...
王晓波, 高强, 宋振岚, 1.大连医科大学附属二院血液科, 2.吉林镍业集团职工医院, 3.大连医科大学附属二院血液科 辽宁大连116023, 4.辽宁大连116023   +6 more
doaj  

胎儿生长受限新生儿脐血血气分析及其临床意义

Zhongguo shiyan zhenduanxue, 2015
目的通过胎儿生长受限新生儿及正常新生儿不同分娩方式下新生儿脐血血气分析,研究胎儿生长受限新生儿脐血血气分析特点及临床意义。方法将2013年我院确诊为胎儿生长受限的孕产妇,顺产的28例为A组,随机选取行择期剖宫产术的30例为B组,随机选取同期适龄胎儿顺产及行择期剖宫产产妇各30例为C组、D组。分别对比各组新生儿的脐动脉血pH、PO2、PCO2、BE、HCO3水平。结果 A组的脐动脉pH、BE、HCO3均低于B组 ...
张晓茗, 折瑞莲, 高宇, 王琳
doaj  

全身麻醉对剖宫产新生儿神经退行性变生物标志物及认知功能影响的病例对照研究

Zhongguo shiyan zhenduanxue, 2022
目的 研究全身麻醉对剖宫产新生儿脐血内神经退行性变生物标志物以及生长期认知发育等功能的影响。方法 纳入在2018年9月至2019年9月间于本院行择期全麻剖宫产的产妇135名（全麻组），及同期入院行椎管内麻醉剖宫产的产妇135名（椎管内麻醉组）。在胎儿娩出后采集2组的脐动脉和脐静脉血，测定血气和神经退行性变生物标志物（S100、Tau蛋白和Activin A）。在儿童生长到12和24月龄时，通过Bayley-III评估量表随访和评估其认知、语言等发育功能情况。结果 椎管内麻醉组的低血压发生率要高于全麻组 ...
周静兰, 周瑶, 周依露, 陶伟民, 徐振东   +4 more
doaj  

Observation on curative effect and nursing care of patients with neonatal hemolytic disease underwent homochronous exchange transfusion of peripheral artery and vein

Huli yanjiu, 2005
[目的]全面了解经外围动静脉换血治疗新生儿溶血病的优缺点,探讨预防和护理并发症的方法。[方法]对采用外围动静脉同步换血的20例新生儿溶血病患儿（外围动静脉组）的临床资料进行回顾性分析,并与同期20例行脐静脉换血患儿（脐静脉组）进行对照。[结果]两组换血成功率均为100%;外围动静脉组手术时间、监护时间、住院时间均较脐静脉组明显缩短,住院费用降低,术后无疤痕及并发症发生。[结论]外围动静脉换血疗法在其适应证范围内可替代脐静脉换血法;优良的护理对提高手术成功率、减少并发症有重要作用。
高敏, 任爱玲, 张玉梅
doaj