Results 11 to 20 of about 1,051 (167)
脑出血是一种由脑实质血管破裂引起的严重疾病,目前尚无有效的治疗方法。研究表明炎症反应在脑出血继发性脑损伤中发挥了重要作用。在出血部位,小胶质细胞被迅速招募并激活,且在促炎型与抑炎型之间动态转变,不同的信号通路可以改变小胶质细胞极化的状态,从而对脑损伤起到调控作用,这提示了小胶质细胞在脑出血继发脑损伤的病理过程中具有复杂的作用机制。促炎型小胶质细胞释放的各种炎症因子介导神经细胞和神经组织的炎症损伤;抑炎型小胶质细胞释放趋化因子、脑源性神经营养因子、抗炎介质等诱导小胶质细胞向病变方向迁移 ...
孔德敏1,邹伟2
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Research progress in neuroimmune disorders in atopic dermatitis [PDF]
Atopic dermatitis (AD) is a chronic inflammatory skin disease with the highest incidence in the world. The main clinical manifestations are eczema-like skin lesions, pruritus and xeroderma.
CHEN Xuanyi, XUAN Zhenquan, YAO Zhirong
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Advances in stem cell therapy for sensory nerve injury [PDF]
Sensory nerves belong to the afferent nerve part of the peripheral nervous system. Their role is to accept the stimuli inside and outside the body and transmit them to the center nerve system to form sensations or reflexes.
CHEN Huidong +3 more
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目的 本国际临床指南由欧洲残疾儿童学会(the European Academy of Childhood Disability,EACD)牵头制定,旨在解决发育性协调障碍(developmental coordination disorder,DCD)的定义、诊断、评估、干预以及与社会心理方面的临床应用关键问题。 方法 本指南针对五个领域的关键问题,通过文献综述和专家团队的正式讨论达成共识。为保证指南的循证基础,以“机制”、“评估”和“干预”为检索词, 对2012年更新以来提出的最新建议以及新增的“社会心理问题”和“青少年/成人”为检索词进行检索。根据牛津大学循证医学中心证据等级 (证据水平 [level of evidence, LOE]1–4) 将结果进行分类,最终转化为指南建议。并由国际 ...
Jing Hua +6 more
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Objective To explore the clinical effect of gait motor imagination therapy on improving motor function of stroke patients with hemiplegia. Methods A total of 120 stroke patients admitted to University of Chinese Academy of Sciences Shenzhen Hospital ...
JI Danting (纪丹婷) +4 more
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Research Progress in the Application of Proteomics andMetabolomics in Bee Products [PDF]
Bee products are gaining increasing popularity among consumers for their high nutritional value and various biological activities. However, adulteration is becoming a prominent problem in the production and sale of bee products, and the mechanisms ...
Congcong LIN, Qun LU, Rui LIU, Yan ZHAO
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Research Progress on the Relationship between Genetic Polymorphism and Violent Behavior of Patients with Schizophrenia [PDF]
Schizophrenia is a common disease characterized by thinking obstructions and accompanied by cognitive, emotional and behavioral disorders. Under the control of psychiatric symptoms, patients with schizophrenia may self-injure or impulsively wound others,
XU Shuo, LIANG Yi-ying, HONG Bin-xue,et al
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菖郁逍遥方治疗慢性乙型肝炎伴抑郁症的临床疗效及作用机制探讨 [PDF]
目的观察菖郁逍遥方治疗慢性乙型肝炎(chronic hepatitis B,CHB)伴抑郁症的临床疗效,并探讨其作用机制。方法 90例慢性CHB伴抑郁症患者,采用随机数字表法分为治疗组45例,对照组45例。在恩替卡韦治疗的基础上,对照组服用氟哌噻吨美利曲辛片;治疗组服用中药复方菖郁逍遥方,疗程12周。以汉密尔顿抑郁量表17项(Hamilton depression scale,HAMD17)评分观察治疗前、治疗中(治疗4周)、治疗后(治疗12周)两组患者的抑郁状态变化;以副反应量表(treatment ...
吴春城 +9 more
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Research Progress on the Influence of Intermittent Fasting on Cardiovascular Disease Risk Factors [PDF]
In recent years, the prevalence and mortality of cardiovascular diseases in China have shown a significant upward trend, cardiovascular disease has become a major disease endangering the health of Chinese residents.
CUI Yanru, CEN Qiuyu, WEI Juanfang, WANG Wenchun, ZHANG Anren
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Progress in Research on Biomarkers of Post-Traumatic Epilepsy [PDF]
Post traumatic epilepsy (PTE) is a serious complication of traumatic brain injury and a difficult problem in forensic justice practice. In recent years, many biomarkers have been applied to the diagnosis, treatment and prognosis of injuries and diseases.
JIA Xiao, ZHOU Feng-juan, DAI Bin-bin,et al
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