, 2016 2005-2006 > Academic research: refereed > Publication in refereed journalVersion of ...
Hui-Chan, CWY, 燕铁斌, 郭友华
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Matrine improves neuroinflammation and diabetes-associated cognitive dysfunction in mice via mTAS2R4 activation [PDF]
Objective To investigate the effect and mechanism of matrine in improving diabetes-associated cognitive dysfunction (DACD) from activation of mouse bitter taste receptor member 4 (mTAS2R4).
Deming WANG +3 more
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The Influence of cAMP on Demyelination of Nerve Fiber after Spinal Cord Injury [PDF]
, 2012 目的：研究脊髓损伤后，在损伤局部持续应用环磷酸腺苷（cAMP）对继发性神经纤维脱髓鞘改变的影响，分析神经纤维脱髓鞘的程度及血清中髓鞘碱性蛋白含量的变化趋势及相互关系，探讨神经纤维脱髓鞘程度与脊髓功能的关系。从而为治疗脊髓损伤提供一个新的思路，并为临床应用环磷酸腺苷（cAMP）提供理论依据。 方法：选取雌性SD大鼠150只，随机分为A、B、C、D组，其中A组及B组各25只，C组及D组每组各50只。各组均行胸12椎体后路椎板切除开窗术，A组不打击脊髓，B组，C组及D组术后应用改良的Allen′s法打击脊髓 ...
李大坤
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Prognostic value of serum growth differentiation factor-15, brain natriuretic peptide and adiponectin in patients with acute myocardial infarction [PDF]
Objective To investigate the expression levels of serum growth differentiation factor-15 (GDF-15), brain natriuretic peptide (BNP), and adiponectin (APN) in patients with acute myocardial infarction (AMI) and their prognostic evaluation value.
GU Peipei*, WANG Haitao, WEI Xiaohui
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Study on the impact of noise exposure on cognitive function [PDF]
Noise, as one of the most common harmful environmental factors in our daily lives, can lead to hearing loss with prolonged exposure. More seriously, it can negatively affect cognitive function. The impact of noise exposure on cognitive abilities involves
HUANG Zhanrong +3 more
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Characterization and function of six histone deacetylase genes in Trichinella spiralis [PDF]
, 2014 旋毛形线虫（Trichinellaspiralis），简称旋毛虫，寄生于人体可以起人旋毛虫病。它不仅能威胁人类健康，还给畜牧业造成损失。分布于全世界，流行于德国、意大利、奥地利、美国、中国等。见于啮齿类动物、猪、熊、人类中。 组蛋白去乙酰化酶(histonedeacetylases，HDACs)是对染色体的结构修饰和基因表达调控发挥着重要的作用的一类蛋白酶。HDACs使组蛋白去乙酰化，导致组蛋白与带负电荷的DNA紧密结合，染色质致密卷曲，基因的转录受到抑制。 本论文研究的hdac-1，hdac-3 ...
邱衡通
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Protective effect of dihydromyricetin against hippocampal neuronal injury caused by iron overload and its mechanism [PDF]
Objective To investigate the protective effect of dihydromyricetin (DMY) against injury of primary hip-pocampal neurons caused by ferric ammonium citrate (FAC) and its mechanism.
SUI Yunjie, MA Zegang
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Two-sample Mendelian randomization study on the causal association between air pollution and Alzheimer′s disease [PDF]
Objective·To explore the causal relationship between air pollution and the risk of Alzheimer′s disease (AD) by using two-sample Mendelian randomization (MR).Methods·Based on the data from the genome-wide association study (GWAS), a two-sample MR analysis
SONG Jiwei +4 more
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Differential Proteome of Cerebral Ganglion Including Neural Connective Induced with both Saponins and Acrylamide in Aplysia [PDF]
, 2008 海兔（Aplysia）归属于腹足纲软体动物，它的中枢神经系统（centralnervoussystem,CNS）是开展分子神经生物学研究的经典模式之一。研究海兔CNS功能蛋白质和多肽结构与功能有助于科学地揭示人及高等动物神经系统的活动规律和调控机制，例如：记忆形成、神经性生理调控和神经系统疾病起因等。三七（Panaxnotoginseng,PN）是中国传统中草药之一，其主要成分为皂甙，具有促智、延缓衰老等保护神经系统功能。 采用薄层层析(TLC)、高效液相色谱(HPLC)和基质辅助激光解吸附飞行时间质谱（
冯丽剑
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