Results 21 to 30 of about 7,498 (186)

Adverse neonatal outcomes in small‐for‐gestational age twins identified using twin vs singleton growth charts: systematic review and meta‐analysis

open access: yesUltrasound in Obstetrics &Gynecology, Volume 66, Issue 6, Page 706-715, December 2025.
ABSTRACT Objective To evaluate the use of twin vs singleton growth charts for detecting small‐for‐gestational‐age (SGA) twins at risk of adverse neonatal outcomes. Methods MEDLINE, EMBASE, CINAHL, Cochrane and Scopus databases were searched electronically from inception to May 2024.
S. Sorrenti   +9 more
wiley   +1 more source

牙周炎与脑小血管病相关性的初步研究

open access: yesZhongguo shiyan zhenduanxue, 2021
牙周炎是口腔内常见疾病,据统计报道,每年约7.43亿人患有重度牙周炎[1]。长期慢性的牙周炎症会破坏牙周支持组织,形成牙列缺损或牙列缺失。严重的牙周炎导致全身炎症反应,可能使脑小血管发生病理改变从而影响大脑正常功能[2]。脑小血管病是痴呆和脑卒中的主要病因,其患病率随着年龄的增长而增加,对老年人的危害极大[3]。
张继禹   +5 more
doaj  

The role of MiR-23b-3p in the epileptogenesis [PDF]

open access: yes, 2016
癫痫是指脑部持续存在能导致癫痫反复发作,并出现相应的神经生物学、认知、心理学,以及社会学等方面的后果的脑部疾患。目前miRNA在癫痫发生发展中的作用引起越来越多的重视。miR-23b-3p是具有多种生物学作用的miRNA,如调节神经元增殖、分化和凋亡等,参与多种神经退行性疾病的病理机制。 本研究通过腹腔注射海人酸(Kainicacid,KA)构建小鼠癫痫模型,发作达到Racine标准的4-5级作为实验组纳入标准,对照组注射相同剂量的生理盐水,并应用荧光定量PCR法对皮层和海马组织中miR-23b-3p ...
战连波
core  

Clip Voice: Misogyny and the Renegotiation of a Gendered Vocal Style in Chinese Digital Discourse

open access: yesJournal of Sociolinguistics, Volume 29, Issue 5, Page 348-359, November 2025.
ABSTRACT The participatory culture of social media allows women's voices to be heard but also parodied and policed. On Chinese social media platforms, where performers rapidly adopt and transform vocal trends for engagement, discourse on gendered vocal styles has proliferated.
Zichuan Yu, Rebecca Lurie Starr
wiley   +1 more source

Cloning, Expression and Immunolocalization of Aspartyl Protease Inhibitor Gene of Angiostrongylus cantonensis [PDF]

open access: yes, 2016
广州管圆线虫(Angiostrongyluscantonensis)是一种人畜共患自然疫源性寄生虫,能引起人的嗜酸性粒细胞增多性脑膜炎,也被称为广州管圆线虫病。其中间宿主是软体动物,例如福寿螺、玛瑙螺等,并以啮齿类动物等作为其终宿主。人类是广州管圆线虫的偶然宿主,因误食寄生有广州管圆线虫的第三期幼虫(L3)的福寿螺等而引起广州管圆线虫病。 寄生虫的天冬氨酸蛋白酶抑制剂(aspartylproteaseinhibitor,API)在寄生虫的寄生生活中起着重要的作用,包括寄生虫的营养摄取,组织入侵,免疫逃避,
曹斌斌
core  

Comparison of open fetal, fetoscopic and postnatal surgical repair for open spina bifida: decision analysis

open access: yesUltrasound in Obstetrics &Gynecology, Volume 66, Issue 4, Page 433-442, October 2025.
ABSTRACT Objective Currently, there are several surgical approaches to manage fetal open spina bifida (OSB), namely postnatal surgical repair, open fetal surgery and its minimally invasive alternative, fetoscopic repair. Our objective was to determine the optimal surgical approach for OSB, weighing the benefits and risks to the fetus and the pregnant ...
Y. Kunpalin   +6 more
wiley   +1 more source

Transcriptomic profiling of dorsal root ganglia in atopic and healthy dogs: A comparative RNA sequencing study with implications in cutaneous itch research

open access: yesVeterinary Dermatology, Volume 36, Issue 4, Page 401-411, August 2025.
Background – Itch is a common symptom in skin disorders. While the neural pathways of itch transmission from the skin to the brain are well‐understood in rodents, the same pathways in dogs remain unclear. The knowledge gap hinders the development of effective treatments for canine itch‐related disorders.
Chie Tamamoto‐Mochizuki   +1 more
wiley   +1 more source

实时荧光定量聚合酶链反应技术对结核性脑膜炎的诊断价值

open access: yesZhongguo shiyan zhenduanxue, 2015
目的探讨实时荧光定量聚合酶链反应技术(RT-PCR)对结核性脑膜炎的诊断价值。方法分别采用涂片法、RT-PCR法对结核性脑膜炎、疑似结核性脑膜炎以及非结核性脑膜炎患者的脑脊液标本进行检测,并对检测结果进行比较分析。结果涂片法共检出10例阳性,其中结核性脑膜炎7例(70.00%),疑似结核性脑膜炎3例(30.00%);RT-PCR法共检出46例阳性,其中结核性脑膜炎31例(67.39%),疑似结核性脑膜炎15例(32.61%)。对结核性脑膜炎患者检测,涂片法阳性率(12.28%)低于RT-PCR法阳性率 ...
杨柳   +7 more
doaj  

Roles of AC-cathB-1, a Cathepsin B-like Cysteine Protease of Angiostrongylus cantonensis, in Host Gut Invasion [PDF]

open access: yes, 2015
广州管圆线虫是引起嗜酸性粒细胞增多性脑膜炎和脑膜脑炎的主要病原生物,该病也因此被命名为广州管圆线虫病。广州管圆虫属于管圆线虫属,中间宿主为软体动物,终末宿主为啮齿类动物,人因误食未煮熟的携带其第三期幼虫(L3)的软体动物而意外感染,L3污染的其他食物或水源也可导致感染。近年来,随着人们饮食习惯的改变和水陆交通日趋发达,该病的流行呈上升趋势。然而,我们在其诊断和治疗方面仍缺乏有效手段,因此对其的进一步研究很有必要。 小肠壁作为机体防御病原体入侵的天然屏障之一 ...
龙瀛
core  

抗N-甲基-D-天冬氨酸受体脑炎与髓鞘少突胶质细胞糖蛋白抗体相关疾病并存的临床特征 [PDF]

open access: yes, 2020
【目的】探讨抗N-甲基-D-天冬氨酸受体(NMDAR)脑炎与髓鞘少突胶质细胞糖蛋白(MOG)抗体相关疾病并存患者的临床特征。【方法】回顾性分析2015 年2 月至2019 年8 月广东省中山大学附属第三医院神经内科和广州市妇女儿童医疗中心神经内科共同收治的36 例抗NMDAR 脑炎患者,其中17 例为与MOG 抗体相关疾病共存的并存组,19  例为单纯抗NMDAR  脑炎的对照组。分析总结两组患者的首发症状、影像学特征、实验室检查、治疗及预后情况。【结果】与对照组比较 ...
吴远华   +6 more
core  

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