Results 21 to 30 of about 49,848 (160)

Advances in Elemene Nanodelivery Systems: From Material Design to Disease Treatment

open access: yesRare Metals, Volume 45, Issue 2, February 2026.
ABSTRACT Elemene (ELE) is a bioactive sesquiterpenoid extracted from traditional Chinese herbs, demonstrating broad‐spectrum antitumor, anti‐inflammatory, and analgesic properties with significant therapeutic potential. However, its clinical utility is constrained by inherent physicochemical limitations, including volatility and hydrophobicity, which ...
Xiao Wang   +9 more
wiley   +1 more source

初诊为抑郁症的老年隐球菌性脑膜炎6例报告 [PDF]

open access: yes, 2019
目的:探讨老年隐球菌性脑膜炎发病特点和误诊原因。方法:分析6例初诊为抑郁症的老年隐球菌性脑膜炎患者的临床表现、脑脊液特点、治疗和预后表现,以明确发病特点和误诊原因。结果:6例病例初期均表现为头晕、失眠、食纳减少;后期出现颅内感染相对特异症状:认知障碍5例、头痛3例、肢体无力3例、发热2例。脑脊液隐球菌培养阳性明确诊断,抗真菌治疗有效。6例均好转,但是2例患者遗留明显后遗症:1例患者遗留明显的认知障碍和双下肢活动受限,1例双眼失明,2例确诊时间为2、4周。结论:老年患者患病后临床症状常不典型 ...
陈星宇   +6 more
core   +1 more source

Adverse neonatal outcomes in small‐for‐gestational age twins identified using twin vs singleton growth charts: systematic review and meta‐analysis

open access: yesUltrasound in Obstetrics &Gynecology, Volume 66, Issue 6, Page 706-715, December 2025.
ABSTRACT Objective To evaluate the use of twin vs singleton growth charts for detecting small‐for‐gestational‐age (SGA) twins at risk of adverse neonatal outcomes. Methods MEDLINE, EMBASE, CINAHL, Cochrane and Scopus databases were searched electronically from inception to May 2024.
S. Sorrenti   +9 more
wiley   +1 more source

Clip Voice: Misogyny and the Renegotiation of a Gendered Vocal Style in Chinese Digital Discourse

open access: yesJournal of Sociolinguistics, Volume 29, Issue 5, Page 348-359, November 2025.
ABSTRACT The participatory culture of social media allows women's voices to be heard but also parodied and policed. On Chinese social media platforms, where performers rapidly adopt and transform vocal trends for engagement, discourse on gendered vocal styles has proliferated.
Zichuan Yu, Rebecca Lurie Starr
wiley   +1 more source

Comparison of open fetal, fetoscopic and postnatal surgical repair for open spina bifida: decision analysis

open access: yesUltrasound in Obstetrics &Gynecology, Volume 66, Issue 4, Page 433-442, October 2025.
ABSTRACT Objective Currently, there are several surgical approaches to manage fetal open spina bifida (OSB), namely postnatal surgical repair, open fetal surgery and its minimally invasive alternative, fetoscopic repair. Our objective was to determine the optimal surgical approach for OSB, weighing the benefits and risks to the fetus and the pregnant ...
Y. Kunpalin   +6 more
wiley   +1 more source

Transcriptomic profiling of dorsal root ganglia in atopic and healthy dogs: A comparative RNA sequencing study with implications in cutaneous itch research

open access: yesVeterinary Dermatology, Volume 36, Issue 4, Page 401-411, August 2025.
Background – Itch is a common symptom in skin disorders. While the neural pathways of itch transmission from the skin to the brain are well‐understood in rodents, the same pathways in dogs remain unclear. The knowledge gap hinders the development of effective treatments for canine itch‐related disorders.
Chie Tamamoto‐Mochizuki   +1 more
wiley   +1 more source

预防流行性脑脊髓膜炎 03-089

open access: yes, 2018
Slide caption: Neisseria meningitidis.标题:脑膜炎双球菌A woman observing the bacteria under a ...

core   +1 more source

Placental biomarker and fetoplacental Doppler abnormalities are strongly associated with placental pathology in pregnancies with small‐for‐gestational‐age fetus: prospective study

open access: yesUltrasound in Obstetrics &Gynecology, Volume 65, Issue 6, Page 749-760, June 2025.
ABSTRACT Objective Placental dysfunction can result in small‐for‐gestational age (SGA) or fetal growth restriction (FGR). The aim of this prospective cohort study was to assess the association of the cerebroplacental ratio (CPR) and other more conventional fetoplacental Doppler indices, circulating placental growth factor (PlGF) levels and soluble fms ...
J. Hong   +6 more
wiley   +1 more source

Combating infections under siege: Healthcare challenges amidst the military assault in Gaza

open access: yesWorld Medical &Health Policy, Volume 17, Issue 1, Page 188-213, March 2025.
Abstract The ongoing Israeli military assault on Gaza has caused a devastating collapse of healthcare infrastructure, resulting in an unprecedented surge in infectious diseases. The destruction of sanitation systems, restrictions on medical supplies, and displacement of civilians have created an environment conducive to the rapid spread of waterborne ...
Bilal Irfan   +24 more
wiley   +1 more source

无乳链球菌致儿童细菌性脑膜炎抗感染实践 [PDF]

open access: yes, 2016
目的分析药师参与的无乳链球菌致儿童细菌性脑膜炎的治疗实例,促进抗感染药物在细菌性脑膜炎的合理使用及探讨全敏感无乳链球菌抗感染治疗不佳情况下的药学思维。方法药师参与无乳链球菌致儿童细菌性脑膜炎病例治疗,对全敏感无乳链球菌抗感染治疗不佳原因进行剖析总结。结果药师对部分抗感染方案给出建议获得采纳后治疗取得进展,针对国内耐药情况对细菌性脑膜炎的经验治疗方案建议采用美罗培南联合万古霉素;对万古霉素进行血药浓度监测并在浓度指导下进行剂量调整 ...
周佳, 颜志文, 陈叶莉
core  

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