Results 11 to 20 of about 64,798 (151)
Zhongguo cuzhong zazhi, 2023 脑出血是一种由脑实质血管破裂引起的严重疾病，目前尚无有效的治疗方法。研究表明炎症反应在脑出血继发性脑损伤中发挥了重要作用。在出血部位，小胶质细胞被迅速招募并激活，且在促炎型与抑炎型之间动态转变，不同的信号通路可以改变小胶质细胞极化的状态，从而对脑损伤起到调控作用，这提示了小胶质细胞在脑出血继发脑损伤的病理过程中具有复杂的作用机制。促炎型小胶质细胞释放的各种炎症因子介导神经细胞和神经组织的炎症损伤；抑炎型小胶质细胞释放趋化因子、脑源性神经营养因子、抗炎介质等诱导小胶质细胞向病变方向迁移 ...
孔德敏1，邹伟2
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Zhongshan Daxue xuebao. Yixue kexue ban, 2021 炎症和免疫是脑血管病病理生理的重要部分，其动态变化影响着脑血管病的进程和预后。缺血性卒中急性期的炎症激活造成大脑病灶的炎症损伤，还参与衰老相关的脑小血管病的脑损害，引起血管性痴呆等认知功能障碍。本文就炎症和免疫与脑血管病相互作用机制的研究进展进行综述，以更好地了解和探索免疫调节在治疗中的潜力。
陆正齐
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Zhongshan Daxue xuebao. Yixue kexue ban, 2008 【目的】 探讨吞咽功能的评估对脑卒中患者发生吸入性肺炎的影响65377;【方法】 对286例脑卒中患者随机分为实验组172例和对照组112例,实验组采用床边吞水试验评估病人的吞咽功能并根据吞咽功能评估结果采取预见性护理干预措施65377;【结果】 实验组没有发生吸入性肺炎,对照组发生吸入性肺炎4例,吸入性肺炎的发生率为3.6%,实验组吸入性肺炎的发生率明显低于对照组(P < 0.05)65377;【结论】 对脑卒中病人进行吞咽功能的评估,能及早进行护理干预,减少患者发生吸入性肺炎 ...
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Mechanisms of bariatric surgery for weight loss and diabetes remission 减重手术减轻体重和缓解糖尿病的机制
Journal of Diabetes, Volume 15, Issue 9, Page 736-752, September 2023., 2023 Highlights Controversial changes in intestinal hormones after bariatric surgery (BS) were summarized. The changes of signaling proteins involved in insulin resistance and the newly proposed changes in growth differentiation factor 15, exosomes, and extracellular vesicles after BS were elucidated.
Mengsha Yin +6 more
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The Association of Retinal age gap with metabolic syndrome and inflammation 视网膜年龄差与代谢综合征和炎症的关系
Journal of Diabetes, Volume 15, Issue 3, Page 237-245, March 2023., 2023 Highlights Retinal age gap is a non‐invasive and cost‐effective aging biomarker. Retinal age gap was significantly associated with metabolic syndrome and inflammation. Retinal age gap could be potentially used as a screening tool for metabolic syndrome in large populations.
Zhuoting Zhu +13 more
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Journal of Diabetes, Volume 14, Issue 12, Page 806-814, December 2022., 2022 Highlights Metformin activates GDF15 expression, which reduces appetite with induction of weight loss in both diabetic and non‐diabetic patients. GDF15 level is linked and correlated with the progression of diabetic complications including thrombosis, diabetic nephropathy, diabetic neuropathy, and diabetic retinopathy. Abstract Type 2 diabetes mellitus
Hayder M. Al‐kuraishy +8 more
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Wireless Communications and Mobile Computing, Volume 2021, Issue 1, 2021., 2021 Clinical named entity recognition (CNER) identifies entities from unstructured medical records and classifies them into predefined categories. It is of great significance for follow‐up clinical studies. Most of the existing CNER methods fail to give enough thought to Chinese radical‐level characteristics and the specialty of the Chinese field.
Yue Wu +6 more
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Wireless Communications and Mobile Computing, Volume 2021, Issue 1, 2021., 2021 Machine reading comprehension (MRC) is a challenging natural language processing (NLP) task. It has a wide application potential in the fields of question answering robots, human‐computer interactions in mobile virtual reality systems, etc. Recently, the emergence of pretrained models (PTMs) has brought this research field into a new era, in which the ...
Changchang Zeng +2 more
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IL-18、IL-23和sRAGE在早产儿脑膜炎诊断中的应用
Zhongguo shiyan zhenduanxue, 2022 目的 探讨白细胞介素18（IL-18）、白细胞介素23（IL-23）和可溶性受体晚期糖基化终产物（sRAGE）在诊断早产儿细菌性脑膜炎中的临床价值。方法 将96例早产儿分为脑脊液（CSF）细菌培养阳性脑膜炎组（26例）、脑脊液细菌培养阴性脑膜炎组（40例）和非脑膜炎组（30例）；测量各组患儿脑脊液中的IL-18、IL-23和sRAGE水平，比较感染和未感染早产儿上述表达的差异，并采用ROC曲线分析单个标志物和标志物联合诊断的灵敏度和特异度。结果脑膜炎早产儿CSF中IL-18、IL ...
李怀玉, 王安萍, 杨萍
doaj
, 2019 目的:探讨老年隐球菌性脑膜炎发病特点和误诊原因。方法:分析6例初诊为抑郁症的老年隐球菌性脑膜炎患者的临床表现、脑脊液特点、治疗和预后表现,以明确发病特点和误诊原因。结果:6例病例初期均表现为头晕、失眠、食纳减少;后期出现颅内感染相对特异症状:认知障碍5例、头痛3例、肢体无力3例、发热2例。脑脊液隐球菌培养阳性明确诊断,抗真菌治疗有效。6例均好转,但是2例患者遗留明显后遗症:1例患者遗留明显的认知障碍和双下肢活动受限,1例双眼失明,2例确诊时间为2、4周。结论:老年患者患病后临床症状常不典型 ...
陈星宇 +6 more
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