Results 71 to 80 of about 1,581 (147)
Development of a prediction model for acute respiratory distress syndrome in ICU patients with acute pancreatitis based on machine learning algorithms [PDF]
"Objective To develop and validate a predictive model based on machine learning algorithms to assess the risk of acute respiratory distress syndrome（ARDS）in patients with acute pancreatitis（AP）admitted to the intensive care unit（ICU）.
REN Xia*，LIU Luojie，ZHA Junjie，YE Ye，XU Xiaodan，YE Hongwei，ZHANG Yan
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降钙素原及N末端钠尿肽前体在老年脓毒性休克病情评估的临床应用研究
Zhongguo shiyan zhenduanxue, 2013 目的降钙素原（PCT）及N末端钠尿肽前体（NT-ProBNP）对老年脓毒性休克病情评估的临床应用价值。方法比较严重脓毒症（80例）及脓毒性休克（67例）PCT、NT-ProBNP差异,比较不同临床结局脓毒性休克PCT、NT-ProBNP差异,研究PCT、NT-ProBNP与急性生理与慢性健康评分（APACHEⅡ评分）相关性。结果脓毒性休克组PCT、NT-ProBNP及APACHEⅡ评分均高于严重脓毒症组,差异均有统计学意义 ...
韩根良
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Expert consensus on the precise classification and diagnosis of acute respiratory distress syndrome [PDF]
Acute respiratory distress syndrome (ARDS) is a common critical illness in clinical practice, with a high mortality rate. Given the limited traditional treatment options for ARDS and the high heterogeneity among patients, most clinical trials have failed
Expert Group for Precise Classification and Diagnosis of Acute Respiratory Distress Syndrome
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Zhongshan Daxue xuebao. Yixue kexue ban, 2013 【目的】 观察ghrelin对脓毒症大鼠肺亚硝酸化应激的影响?【方法】 采用盲肠结扎穿孔(CLP)方法制备脓毒症模型,24只雄性SD大鼠按随机区组设计方法随机分为3组:假手术组?脓毒症组(以CLP表示)和ghrelin组?ghrelin组于术后3 h及15 h腹腔注射ghrelin,各组于术后20 h采集标本?我们检测血清超氧化物歧化酶(SOD)活性?肺湿/干重?肺组织诱导型一氧化氮合成酶(iNOS)和硝基酪氨酸的表达水平?【结果】 与假手术组[(93.17 ± 0.54)%]对比,脓毒症组[(85 ...
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cTnI、CK-MB及乳酸联合检测对急诊老年严重脓毒症及脓毒症休克患者预后的评估
Zhongguo shiyan zhenduanxue, 2017 目的研究急诊老年严重脓毒症及脓毒性休克患者血浆心肌肌钙蛋白I（cTnI）、肌酸激酶同工酶（CK-MB）及动脉血乳酸水平的变化及其对预后的评估。方法收集首都医科大学宣武医院急诊老年严重脓毒症和脓毒性休克患者98例,就诊后予cTnI、CK-MB、乳酸等检查,并行APACHEⅡ评分（Acute Physiology and Chronic Health EvaluationⅡ）和SOFA（Sequential Organ Failure Assessment,SOFA）评分,早期目标导向性治疗（EGDT ...
王春源 +4 more
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微生物与人体免疫系统的互动一直是生物医学研究的焦点。新一代测序发现不仅肠道，呼吸道也存在着微生物群，且肠-肺微生物群之间通过免疫细胞及其活性因子等形成了一个相互关联的网络。本综述旨在探讨肠道和肺部微生物群如何调节免疫应答，包括其在局部和全身免疫调节中的作用；同时，解析肠-肺轴之间的免疫联系 ...
张萌, 杨正飞
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Correlation of serum activated protein C and 4⁃hydroxynonenal levels with myocardial injury in severe pneumonia and their prognostic prediction [PDF]
Objective To investigate the changes of serum activated protein C（APC）and 4 ⁃ hydroxynonenal（4 ⁃ HNE）levels in patients with severe pneumonia，and analyze their correlation with patient outcomes and myocardial injury.
GAO Tian*，WANG Wei，WANG Ling，QIAN li，HAN fei，WANG Shuo，YE Xiaoman，YIN Jie，ZHAI Aiqin
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Ghrelin对脓毒症大鼠肺泡巨噬细胞炎症信号通路Akt、NF-κB和iNOS的影响
Zhongshan Daxue xuebao. Yixue kexue ban, 2018 ： 【目的】观察生长激素释放肽（ghrelin）对脓毒症大鼠肺泡巨噬细胞（AM）炎症信号通路蛋白激酶 B （Akt）、核因子-κB（NF-κB）及诱导型一氧化氮合成酶（iNOS）的影响。【方法】24只SD雄性大鼠随机分为假手术 （Sham）组、脓毒症（CLP）组、ghrelin干预（CLP+ghrelin）组与ghrelin对照（Sham+ghrelin）组。盲肠结扎穿孔（CLP）构建 大鼠脓毒症模型，分别于术后3 h与5 h腹腔注射20 nmol/kg ghrelin进行干预 ...
郑海崇 +3 more
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Changes of serum high mobility group box 1 and soluble triggering receptor expressed on myeloid cells-1 in patients with multiple injuries and their prognostic significance [PDF]
Objective·To detect the serum levels of high mobility group box 1 (HMGB1) and soluble triggering receptor expressed on myeloid cells-1 (sTREM-1) in patients with multiple injuries at different time points, and to analyze their correlation with disease ...
DU Chuanchong +6 more
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Zhongguo shiyan zhenduanxue, 2019 目的研究血清总胆红素在烧伤伴发脓毒症患者血清中的水平变化,分析其与患者预后的关系。方法回顾性选取本院2017年2月-2018年2月收治的烧伤伴发脓毒症患者96例为研究对象,按照是否发生预后死亡分为生存组59例和死亡组37例,同时另取本院收治的烧伤非脓毒症患者50例为对照组。收集患者入院当日及健康志愿者白细胞计数(WBC)、血小板计数(PLT)、中性粒细胞比率(NE)、C-反应蛋白(CRP)、白蛋白(Alb)水平,采用全自动生化分析仪检测患者入院当日及确诊伴发脓毒症第1、3、5、7天时的血清总胆红素 ...
马常明 +5 more
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