Results 91 to 100 of about 2,785 (150)
PBX1-SIRT1-PARP1轴调控膀胱癌细胞增殖、迁移及凋亡的机制研究
Zhongguo shiyan zhenduanxue目的探讨 PBX1-SIRT1-PARP1 轴在膀胱癌细胞中的功能及分子机制。方法采用生信分析方法预测PBX1与SIRT1基因启动子间的潜在结合位点；收集临床样本，使用qRT-PCR法比较癌旁和膀胱癌组织以及膀胱癌细胞系与正常尿路上皮细胞系中PBX1、SIRT1、PARP1基因表达水平；建立PBX1过表达和敲低细胞系，并联合使用SIRT1抑制剂，比较各组［Vector 对照组、PBX1 过表达组（PBX1-OE）、PBX1 敲低组（shPBX1）及 PBX1-OE + SIRT1 抑制组（EX-527 ...
马圣超 +4 more
doaj
Urinary Diversion in Patients Treated with Pelvic Irradiation : Transverse Colon Conduit Revisited [PDF]
, 2014 In patients receiving pelvic irradiation for gynecological or genitourinary malignancies, urinary diversion is sometimes required for complete resection of malignancies or treatment of urological complications by irradiation.
井上, 貴博 +10 more
core
Zhongguo shiyan zhenduanxue, 2011 膀胱癌在我国占泌尿系恶性肿瘤的首位,发病率占全身恶性肿瘤的4%[1]。我们已步入快速型社会,人们的生活习惯越发不规律,而膀胱癌的发病率亦随之增高。随着超声技术的不断发展,超声在膀胱癌的早期诊断上也发挥越来越重要的作用 ...
李秀昆, 刘磊, 赵萍, 于杰
doaj
Zhongguo shiyan zhenduanxue目的通过检测ARPC3在膀胱癌患者尿液中的表达情况，探究其在膀胱癌发生发展中的意义。方法应用二维液相色谱-质谱联用技术筛选膀胱癌患者尿液中的差异表达蛋白，并通过酶联免疫吸附试验加以验证。结果二维液相色谱-质谱技术共获得了11个差异表达蛋白。6个上调表达蛋白，5个下调表达蛋白，目标蛋白ARPC3为其中一个上调表达蛋白，酶联免疫吸附试验结果与其一致。结论ARPC3在膀胱癌尿液中显著高表达，ARPC3可能在膀胱癌的发生发展中起一定作用。
阿 力木·罗合曼 +3 more
doaj
Zhongguo shiyan zhenduanxue, 2015 目的探讨微小染色体维持蛋白(MCM)在膀胱肿瘤组织和尿脱落细胞中的表达及临床意义。方法收集本院2012年8月—2013年8月住院患者及健康志愿者的尿脱落细胞或膀胱组织标本,对其进行MCM5检测。结果1膀胱癌患者在不同病理分级、临床分期MCM/β-actin的差异有统计学意义 ...
曹冉华 +4 more
doaj
[Prognostic analysis of laparoscopic simultaneous radical cystectomy and nephroureterectomy]. [PDF]
Beijing Da Xue Xue Bao Yi Xue BanLi S +9 more
europepmc +1 more source
[Pirfenidone inhibits bladder cancer xenograft growth in mice by regulating regulatory T cells]. [PDF]
Nan Fang Yi Ke Da Xue Xue BaoZhang H +5 more
europepmc +1 more source
[Apelin promotes proliferation, migration, and angiogenesis in bladder cancer by activating the FGF2/FGFR1 pathway]. [PDF]
Nan Fang Yi Ke Da Xue Xue BaoSu W +6 more
europepmc +1 more source
[Risk assessment of perioperative adverse events and management of antiplatelet therapy in patients with bladder cancer and coronary atherosclerotic heart disease undergoing transurethral resection of bladder cancer]. [PDF]
Beijing Da Xue Xue Bao Yi Xue BanMiao Q +8 more
europepmc +1 more source