Results 11 to 20 of about 7,359 (155)
Highlights Phosphoinositide 3‐kinase (PI3K)/Akt signaling is an emerging promising therapeutic target for diabetes. Modulation of the PI3K/Akt signaling pathway, via protein and peptide‐based biologics, parasite‐derived molecules, plant extracts, or through microRNA interactions, will regulate the processes that determine the function of β‐cells and ...
Inah Camaya +2 more
wiley +1 more source
Highlights This prospective study compares 15 patients with immune‐checkpoint induced diabetes mellitus (CPI‐DM) with a propensity score matched cohort of patients with other diabetes types. Diabetic ketoacidosis at onset and autoimmune comorbidity is more frequent in CPI‐DM patients. This can be avoided by regular glucose measurements and education on
Sascha R. Tittel +10 more
wiley +1 more source
Highlights Several psychiatric disorders were associated with levothyroxine therapy (LT4). Depression, anxiety disorders, and attention‐deficit/hyperactivity disorder showed the strongest relation to LT4. Thyroid autoimmunity itself (no LT4) was not associated with psychiatric disorders.
Alexander Eckert +9 more
wiley +1 more source
Autoimmune polyendocrine syndrome type 2 complicated with hyperthyroidism crisis and diabetic acute complications: a case report and literature review [PDF]
Objective To enhance clinicians’ diagnosis and treatment capability for autoimmune polyendocrine syndrome type 2 (APS-2),and reduce missed diagnosis and misdiagnosis.
Jian Li, Wu Qinan, Zhao Qiquan, LYU Xinlu
core +1 more source
1型糖尿病(T1DM)是一种以高血糖为主要直接表现的自身免疫性疾病。我国发病率增加明显,疾病负担重,患者身心健康及生活质量均受到严重影响,治疗现状急需改进,故倍受关注[1]。且因内分泌系统疾病与疾病自身免疫过程的密切相互作用,使得T1DM患者更易合并其他自身免疫性疾病,进而有更大可能被诊断为自身免疫性多内分泌腺病综合征(APS)。
董佳婧, 刘殿媛, 王清
doaj
桥本甲状腺炎(HT)是最常见的自身免疫性甲状腺疾病(AITD),主要表现为甲状腺功能减退,病因与自身免疫功能紊乱相关,部分患者可合并其他自身免疫性疾病,如自身免疫性肾病、系统性红斑狼疮、干燥综合征、类风湿关节炎等。当AITD伴有蛋白尿时称为AITD肾病,其病理类型多为膜性肾病,伴IgA肾病(IgAN)报道不多,本文报道1例桥本甲状腺炎伴IgA肾病的病例,以期为临床实践提供参考。
陈奕颖, 付少杰, 黄文洁, 陈志
doaj
Diagnostic thinking of renal capillary endothelial cell hyperplasia [PDF]
The diseases pathologically manifested with endothelial cell hyperplasia can present with multiple clinical manifestations, which correspond to different types of clinical diseases.
Lü Guangna, Yan Yu
core +1 more source
Ethical Reflection on Standardized Management of Intestinal Microbiota Transplantation [PDF]
肠道微生态系统是人体健康所必需的重要且复杂的生物系统。肠道微生态系统的紊乱参与人体多种疾病的发生发展过程。而肠菌移植技术可有效调节肠道菌群,修复失衡的肠道微生态,为当今多种胃肠道及胃肠以外疾病的治疗带来新的突破。然而,目前尚缺乏完整的、系统性的肠菌移植技术管理规范。就肠菌移植技术规范化管理所涉及的内容进行探讨,并从医学伦理学角度思考规范化管理中所涉及的伦理问题,以期推动肠菌移植技术的临床应用。Intestinal microecology is an important and complex ...
任建林 +4 more
core +1 more source
抗中性粒细胞胞质抗体(antineutrophil cytoplasmic autoantibody,ANCA)相关性小血管炎(ANCA associated small vessel vasculiltis,AASV)是以中性粒细胞、单核细胞胞质成分为靶抗原的一组自身免疫性系统性疾病,主要包括肉芽肿性多血管炎、显微镜下多血管炎和嗜酸性肉芽肿性多血管炎。福建省自然科学基金(No ...
彭卫华, 陈凌舟
core +1 more source

