Results 1 to 10 of about 9,588 (160)
[Clinical Value of Autoantibody Prognostic Markers in Tumor Immune Checkpoint Inhibitor Therapy]. [PDF]
Zhongguo Fei Ai Za Zhi, 2022 血清自身抗体标志物具有标本易获取、检测技术简便、可实现实时动态监测等优势。随着免疫检查点抑制剂在肿瘤治疗中的广泛应用，自身抗体标志物在肿瘤免疫检查点抑制剂治疗疗效、预后及免疫相关不良事件（immune related adverse events, irAEs）发生预测方面的报道逐渐增多，显示出了良好的预测潜力。本文主要探讨自身抗体标志物在肿瘤免疫治疗疗效、预后及irAE预测方面的研究进展，并对未来前景做出展望。
Dai L, Han X.
europepmc +2 more sources
Clinical research on progress of antinuclear antibody in rheumatoid arthritis [PDF]
, 2023 Rheumatoid arthritis (RA) is a common chronic, systemic autoimmune disease characterized by erosive arthritis, with a global prevalence of 0.25% to 1.00%, which may ultimately lead to joint deformity and loss of function.
LI Yuan, ZHANG Le, YIN Hanlin, ZHENG Bing, LÜ Liangjing
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Expression and clinical significance of serum complement and IL-25 in systemic lupus erythematosus [PDF]
, 2022 Objective To determine the differences in the expression of serum complement （C） and IL-25 in systemic lupus erythematosus （SLE） involved with single or multi-organ systems， and analyze the correlation between serum C3， C4， CH50， IL-25， C-reactive ...
Wang Yang, Luo Yuhong, Liao Yuan
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常在伴有肺纤维化的系统性硬化症患者中检测到抗 C1q 自身抗体
British Journal of Dermatology, 2019 系统性硬化症 (SSc) 是一种自身免疫性疾病,它意味着通常负责对抗疾病的身体免疫系统会错误地瞄准身体的健康部位,而SSc患者会产生针对自身组织的抗体(“自身抗体”)。广泛的增厚和瘢痕组织(纤维化)是这种疾病的主要特征,并且原因是胶原蛋白的过度生成。小血管也会发生变化。当纤维化发生在肺(肺纤维化)时,它可以导致高血压动脉进入肺,而这可能会危及生命。这种疾病在女性中比较常见。根据皮肤受累的程度,SSc 可能是局部的,也可能是广泛的。尽管引起 SSc 的原因还没有完全弄清楚 ...
Christos Liaskos +9 more
semanticscholar +1 more source
Zhongguo shiyan zhenduanxue, 2021 目的筛查与肝癌(HCC)相关的自身抗体并对其诊断肝癌的临床价值进行初步评估。方法制备用于自身抗体多重检测的液相芯片,对40例肝炎、32例肝硬化、48例肝癌及30例健康对照组血清进行检测,比较自身抗体IgG水平,筛选与肝癌相关的自身抗体,绘制ROC曲线评估其肝癌的诊断价值,并分析肝癌相关自身抗体与常见生化指标的相关性。结果肝炎、肝硬化、肝癌组的SSA/Ro、tTG、LC1、PR3、Scl-70、Mi-2、MPO和TIF1-γ自身抗体水平均显著高于正常对照组 ...
肖静 +8 more
doaj
Beyond conventional care : developing novel therapeutic approaches to combat arthritis [PDF]
, 2023 Rheumatoid arthritis (RA) is an autoimmune disorder without a definitive cure. Although RA is driven by systemic autoimmunity, its most pronounced manifestation is organspecific inflammation, particularly synovitis in joints.
Xu, Zhongwei
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Zhongguo shiyan zhenduanxue, 2023 目的 探究肿瘤相关抗原(TAAs)LAMR1、ENO1自身抗体在非小细胞肺癌(NSCLC)早期诊断中的价值。方法 收集220例NSCLC患者和220例健康对照者血清，用ELISA方法检测血清中LAMR1、ENO1自身抗体，分析TAAs自身抗体及联合检测的诊断价值。结果 NSCLC患者血清中LAMR1、ENO1自身抗体水平上调 ...
刘欣桐 +5 more
doaj
Evaluation of medication treatment for Alzheimer's disease on clinical evidence [PDF]
, 2014 Objective To formulate the best treatment plan for Alzheimer's disease patients by evaluating the therapeutic efficacy and side effect of various evidence-based programs.
Ling LIU +3 more
core +2 more sources
Clinical analysis of rituximab for adult refractory primary membranous nephropathy [PDF]
, 2023 Objective·To evaluate clinical efficacy and safety of rituximab (RTX) in the patients with refractory primary membranous nephropathy (PMN).Methods·A retrospective analysis was carried out on the patients with refractory PMN, who had recurred or had not ...
BAI Shoujun +4 more
core +1 more source
A Novel Method for Detecting p53 Autoantibodies in Sera of Patients with NSCLC [PDF]
, 2009 Background and objective Serum autoantibody detection is useful means for the early diagnosis and prognosis of cancer. So our objective was to synthesize peptide array to analyse p53 autoantibodies in the sera of patients with non small cell lung cancer (
Kai TANG +4 more
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