Results 11 to 20 of about 26,968 (119)

An Organo‐Pt(II) Photosensitizer With Robust Photo‐Assisted Antibacterial and Wound Recovery Performances in Diabetic Mice Wound Model

open access: yesRare Metals, Volume 45, Issue 7, July 2026.
ABSTRACT The pathogenesis of diabetic foot ulcers is complex, often involving polymicrobial infection and persistent inflammatory responses, which lead to delayed or nonhealing wounds, posing a formidable clinical challenge. Existing photodynamic therapy reagents and traditional treatments generally address only a single pathological aspect, and the ...
Yu Zhang   +16 more
wiley   +1 more source

血清C-反应蛋白和胱抑素-C检测在2型糖尿病肾病早期诊断中的价值

open access: yesZhongguo shiyan zhenduanxue, 2020
2型糖尿病是糖尿病中最常见的一种类型,作为慢性终身代谢性疾病,其致残、致死率较高,发生2型糖尿病后若血糖未得到较好的控制,随着病情进展可导致各种并发症,糖尿病肾病是最严重的并发症之一,早期糖尿病肾病往往无明显症状、体征,其可从不同途径对肾脏造成损害,导致肾功能衰退、衰竭,是2型糖尿病患者残疾或死亡的一个主要影响因素[1]。
宋继英
doaj  

Prenatal diagnosis of cardiac rhabdomyoma: implications for predicting tuberous sclerosis complex and guiding perinatal management

open access: yesUltrasound in Obstetrics &Gynecology, Volume 68, Issue 1, Page 88-98, July 2026.
ABSTRACT Objective To identify prenatal predictors of tuberous sclerosis complex (TSC) in fetuses with one or more cardiac rhabdomyomas (CR), evaluate an integrated multimodal diagnostic workflow using fetal magnetic resonance imaging (MRI) and trio whole‐exome sequencing (trio‐WES) and characterize perinatal outcomes.
X. Cai   +8 more
wiley   +1 more source

遗传性肾脏病基因诊断和高通量测序技术在诊断中的应用进展

open access: yesLinchuang shenzangbing zazhi, 2016
一、遗传性肾脏病的诊断1.遗传性疾病概述遗传性疾病包括单基因遗传病、多基因遗传病和染色体病,单基因遗传病种类多但发生率低,大多是罕见病,大约7 000多种,是由一个基因的序列异常导致的遗传性疾病,又可以分为常染色体隐性遗传病、常染色体显性遗传病和性连锁遗传和线粒体病。多基因遗传疾病约有100多种,都是常见疾病 ...
周建华
doaj  

Risk of minor congenital heart defect in infants conceived via assisted reproductive technology: cohort study from the Copenhagen Baby Heart Study

open access: yesUltrasound in Obstetrics &Gynecology, Volume 68, Issue 1, Page 59-67, July 2026.
ABSTRACT Objective Infertility affects up to 20% of couples in high‐income countries, which has led to an increased use of assisted reproductive technology (ART). While previous studies have linked ART to a higher risk of major congenital heart defects (CHD), less is known about the associated risk of minor CHD.
F. Kyhl‐Svart   +16 more
wiley   +1 more source

1型心肾综合征的发病机制研究进展

open access: yesZhongguo shiyan zhenduanxue, 2013
1型心肾综合征(CRS)是指急性失代偿期心衰(ADHF)、急性冠脉综合征、急性心源性休克以及心脏外科手术、冠状动脉造影等相关操作引起的急性肾损伤(AKI)。实验证明,多种病理生理机制同时或续贯作用致血肌酐升高、少尿、利尿剂抵抗,使失代偿期心衰患者病情加重,导致心肾综合征的发生。而患有慢性肾脏疾病的情况下,肥胖、恶病质、高血压、糖尿病、蛋白尿、钠水潴留、贫血、重叠感染、免疫反应、脓毒血症以及医源性因素导致了1型心肾综合征的发生。氧化应激是导致心肾损伤,发生CRS的最终共同通路 ...
李明   +4 more
doaj  

Titanium Implant Abutments With Polydopamine‐Mesoporous Cerium Dioxide Coatings for Enhanced Antibacterial, Anti‐Inflammatory, and Soft Tissue Integration Properties

open access: yesRare Metals, Volume 45, Issue 6, June 2026.
ABSTRACT The poor soft tissue integration around titanium implants creates a microgap that serves as a pathway for pathogen invasion, resulting in infection, inflammation, and the progression of peri‐implantitis. As the implant’s transmucosal component, the abutment determines the degree of peri‐implant soft tissue attachment.
Xuan Li   +7 more
wiley   +1 more source

美洲红鹮源嗜水气单胞菌的分离与鉴定

open access: yes野生动物学报, 2018
为了确定导致美洲红鹮(Eudocimus ruber)肝脏血肿、出血性肠炎的病原,从美洲红鹮的肝脏、肠道和饲喂美洲红鹮的小黄鱼肠道内容物分离得到3株革兰氏阴性杆菌,并对其进行生化鉴定、药敏试验、小鼠致病性试验,同时观察死亡红鹮的组织病理学变化。结果表明,分离到的3株细菌通过生化鉴定均为嗜水气单胞菌(Aeromonas hydrophila),具有α溶血,药敏试验显示不属于耐药菌株,对小白鼠具有致病性。病理学诊断中,肝脏以血栓为主、肠道黏膜层多处出现肉芽肿。美洲红鹮因致病性嗜水气单胞菌导致死亡。
陈 蓉 周 薇 陈 楠 章小小 邓长林
doaj  

Changing trends in prenatal screening and treatment of cytomegalovirus infection in France: 7‐year national cohort study (2017–2023)

open access: yesUltrasound in Obstetrics &Gynecology, Volume 67, Issue 6, Page 756-763, June 2026.
ABSTRACT Objectives Cytomegalovirus (CMV) is the leading cause of congenital infectious neurosensory impairment. We aimed to present national epidemiological data on maternal CMV infection during pregnancy in France, focusing in particular on primary infection in the periconceptional period or first trimester, and to assess the impact of changes in ...
P. Coste‐Mazeau   +176 more
wiley   +1 more source

外伤性眼内炎的病原学诊断及相关因素分析

open access: yesZhongguo shiyan zhenduanxue, 2013
眼内炎是非常凶险的感染性致盲性眼病,常常造成视功能损害甚至导致视力丧失更有甚者眼球摘除。眼外伤特别是开放性眼外伤,因眼球壁的完整性被破坏,病原微生物易于经过开放的伤口或伴随致伤物进入眼内从而引起化脓性炎症。因眼外伤导致的眼内炎早期诊断,病原学检查,早期治疗 ...
尚彦霞
doaj  

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