Results 61 to 70 of about 26,803 (169)
Functional Characterization of AtST39 in Stress Response and AtMPA Mediating Pollen Development [PDF]
, 2012 基因芯片显示番茄细菌性叶斑病原菌Pseudomonassyringaepv.tomatoDC3000(PstDC3000)，干旱、冷和盐等逆境处理及在开花关键基因lfy突变体中都能够上调AtST39（At3g46110）基因表达；AtMPA（At1g05577）在拟南芥单核花粉粒向三核花粉发育的过程中特异性表达。但是AtST39参与胁迫和AtMPA在介导花粉发育的分子机制知之甚少。我们主要对AtST39进行了探索研究，结果如下： （1）NCBI数据库显示YWC基因家族共有185个蛋白家族成员 ...
肖世民
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Veterinary Dermatology, Volume 37, Issue 1, Page 34-44, February 2026.Background: The chronic and multifactorial character of canine atopic dermatitis (cAD) often leads to poor disease control and treatment dissatisfaction. Environmental factors are likely to contribute to the disease development and may play a more important role than assumed previously.
Patricia Clara‐Maria Rhodius +11 more
wiley +1 more source
Zhongguo shiyan zhenduanxue, 2019 目的近年来我国的病原生物安全防护工作越来越被重视,所以在医学病原微生物肠道杆菌实验教学中,根据卫生部公布的《人间传染的病原微生物名录》,将肠道致病微生物列为第二类病原微生物,属高致病性病原微生物。方法所以在教学中肠道致病伤寒杆菌减毒株的研究迫在眉睫,特此设计了肠道伤寒杆菌的减毒株实验。结果通过肠道伤寒杆菌减毒株实验,使得肠道伤寒实验无毒性,保持生物学性状。结论避免了学生病原微生物学实验中的感染,提高了病原微生物实验教学的安全性,保证医学高校学生学习到真正的肠道致病菌的生化特性,同时保证了生物安全。
于军, 贺丹, 张灵, 李洪岩
doaj
Screening and application of aptamers to Staphylococcus aureus Toxic Shock Syndrome Toxin-1 [PDF]
, 2016 摘要 目的：金黄色葡萄球菌(Staphylococcusaureus)分泌的毒性休克综合征毒素-1(ToxicShockSyndromeToxin-1，TSST-1)引发中毒性休克综合征(ToxicShockSyndrome，TSS)，通过激活T淋巴细胞使其活化、增殖，引起强烈的免疫应答。目前针对TSST-1本身的治疗手段不多，合成寡核苷酸文库和亲和力筛选作为获得高亲和力、高特异性适配体(Aptamer)的一种方便、快捷、有效的方法。本研究利用指数富集的配体系统进化技术 ...
陈弘炜
core
Rare Metals, Volume 45, Issue 1, January 2026.ABSTRACT The escalating issue of drug‐resistant pathogens, largely driven by the overuse of conventional antibiotics, has become a significant global health threat. Developing alternative therapeutic strategies and fabricating natural biological enzyme materials that mimic the high efficiency, selectivity, and mild‐operating conditions of natural ...
Shuai He +11 more
wiley +1 more source
Zhongguo shiyan zhenduanxue, 2012 急性心肌梗死（acute myocardial infarction,AMI）是因持久而严重的心肌缺血所致的部分心肌急性坏死,缺血常由冠状动脉急性闭塞导致血流中断,是缺血性心脏病的表现之一[1],也是临床上较为常见的多发病,发病急并且病死率高,是全球性致死和严重致残的原因之一[2]。因此对急性心肌梗死早期发现、早期诊断和早期治疗就是抢救的关键。目前对AMI的预防和诊断是研究的热点问题,而临床上对AMI的诊断主要是通过心绞痛前驱症状、体征、心电图 ...
刘艳
doaj
Treatment of refractory severe dry eye with 0.1% tacrolimus eyedrops [PDF]
, 2016 目的：评估0.1%他克莫司滴眼液治疗难治性重度干眼疗效。 方法：本研究招募已使用人工泪液合并激素治疗半年或半年以上，但干眼症状及体征未见明显缓解的重度干眼患者26名。所有给予0.1%他克莫司滴眼液合并人工泪液治疗，并于治疗前、治疗后1月、2月及3月观察干眼相关临床指标，包括：干眼症状评分(OcularSurfaceDiseaseIndex，OSDI)、泪膜破裂时间(Tearbreakuptime，TBUT)、泪液分泌试验(SchirmerI)、角膜荧光素钠染色评分 ...
杨舒
core
Ultrasound in Obstetrics &Gynecology, Volume 67, Issue 1, Page 79-88, January 2026.ABSTRACT Objective To evaluate the proportion of optimal assessments of endometrial thickness (ET) achieved by transvaginal ultrasound (TVS) compared with a multimodal (MM) sonographic approach in women with abnormal uterine bleeding (AUB). Methods This prospective observational study was a subset of the EPI‐SURE study conducted between June and ...
S. Nijjar +5 more
wiley +1 more source
Ultrasound in Obstetrics &Gynecology, Volume 67, Issue 1, Page 27-33, January 2026.ABSTRACT Objective To assess the effectiveness of the first‐trimester anomaly scan (FTAS) performed as part of a centrally steered national screening program in The Netherlands by investigating false‐negative cases with a fetal structural anomaly that was not detected at the FTAS.
K. Bronsgeest +18 more
wiley +1 more source
胸腺肽α1对老年慢性阻塞性肺疾病急性发作患者细胞免疫功能的影响
Zhongguo shiyan zhenduanxue, 2012 慢性阻塞性肺疾病（COPD）是呼吸系统常见疾病,常见于老年患者,因为机体慢性缺氧、疾病全身炎症反应可致免疫功能下降,后者又使机体更容易招致感染,加速肺功能的损害,增加患者的致残率及死亡率。免疫增强剂能提高机体的免疫力,减少机体受感染的机会。本文探讨胸腺肽α1治疗后对老年慢性阻塞性肺疾病急性发作（AECOPD）患者免疫功能影响及临床疗效。
金艳坤 +5 more
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