Results 11 to 20 of about 3,926 (133)
[Antibacterial activity and mechanism of the antiparasitic drug resorantel against <i>Staphylococcus epidermidis</i>]. [PDF]
Zhong Nan Da Xue Xue Bao Yi Xue Ban目的 表皮葡萄球菌是临床常见的机会致病菌，抗生素滥用致其耐药性不断攀升，治疗难度显著加大。药物再利用具有成本低、安全性高、周期短等优势，是应对耐药菌感染的有效策略。本研究旨在探究抗寄生虫药物雷琐太尔对表皮葡萄球菌的抗菌活性，并初步阐明其作用机制。 方法 采用微量肉汤稀释法测定雷琐太尔对表皮葡萄球菌的最低抑制浓度(minimal inhibitory concentration，MIC)和最低杀菌浓度(minimum bactericidal concentration，MBC)。采用纸片扩散法、2, 3-
Guo S +6 more
europepmc +2 more sources
Synergistic antibacterial effects of pinaverium bromide and oxacillin against <i>Staphylococcus epidermidis</i>. [PDF]
Zhong Nan Da Xue Xue Bao Yi Xue Ban目的 表皮葡萄球菌能黏附于医疗器械表面形成高耐药的生物被膜，针对表皮葡萄球菌及其生物被膜的新型抗菌药物研发已成为研究热点。本研究通过药物重新利用，探讨L型钙离子通道阻断剂匹维溴铵(pinaverium bromide，PVB)与苯唑西林(oxacillin，OXA)联合使用对表皮葡萄球菌的抗菌作用。 方法 表皮葡萄球菌临床菌株于2022年1至9月收集于中南大学湘雅三医院检验科。通过微量肉汤稀释实验检测PVB和OXA的最低抑菌浓度(minimal inhibitory concentration，MIC)。
Yuan L, She P.
europepmc +2 more sources
金黄色葡萄球菌食物中毒的多重PCR快速检测及产肠毒素耐药分析
亚洲临床医学杂志, 2020 目的：探究金黄色葡萄球菌食物中毒的多重PCR快速检测及产肠毒素耐药。方法：收集环境涂抹物7份，提取总样本DNA对14种食源性致病菌多重PCR检测，检测样品葡萄球菌肠毒素ELISA。并按照食品安全规定分离鉴定金黄色葡萄球菌，分离的菌株分析其耐药与肠毒素基因分型（SEA-SEE）。结果：多重PCR与ELISA检测台面涂抹物和病例中样本金黄色葡萄球菌与肠毒素均是阳性。经分离得出金黄色葡萄球菌3株、10株，分别带有肠毒素基因，台面涂抹物与病例样本均带有毒素基因分离株，并带有相同肠毒素基因的菌株耐药效果一致 ...
磊 刘
semanticscholar +1 more source
Veterinary Dermatology, Volume 34, Issue 6, Page 489-494, December 2023., 2023 Background – Dilute sodium hypochlorite (bleach) baths at 0.005% concentration twice weekly have been shown to markedly reduce the severity of atopic dermatitis in children, yet no tolerability and efficacy data are available for this treatment in dogs.
Frane Banovic +4 more
wiley +1 more source
Veterinary Dermatology, Volume 34, Issue 6, Page 586-596, December 2023., 2023 Background – In clinical practice, the diagnosis of otitis externa (OE) normally is based on otoscopic examination and cytological findings, followed by empirical treatment with topic drugs. Biofilm‐producing bacteria are frequently present in OE, even if its presence is often underdiagnosed. Hypothesis/Objectives – The primary aim of this study was to
Luca Luciani +6 more
wiley +1 more source
Journal of Diabetes, Volume 15, Issue 4, Page 332-337, April 2023., 2023 Abstract Background Diabetic foot infection, particularly osteomyelitis, is a major risk factor of amputation in persons with diabetes. Bone biopsy with microbial examination is considered the gold standard of diagnosis of osteomyelitis, providing information about the offending pathogens as well as their antibiotics susceptibility.
Hassan Al‐Balas +3 more
wiley +1 more source
The nose is not enough: Multi‐site sampling is best for MRSP detection in dogs and households
Veterinary Dermatology, Volume 33, Issue 6, Page 576-580, December 2022., 2022 Abstract Background Following recovery from meticillin‐resistant Staphylococcus pseudintermedius (MRSP) infection of any type, dogs may continue to carry MRSP asymptomatically on skin and mucosae, contributing to the spread of this multidrug‐resistant, veterinary hospital‐associated pathogen with zoonotic potential to others and into the environment ...
Sian‐Marie Frosini +3 more
wiley +1 more source
Veterinary Dermatology, Volume 33, Issue 1, Page 17-e6, February 2022., 2022 Background – Because of the increased incidence of multidrug‐resistant (MDR) bacteria, the use of disinfectants over antibiotics has been encouraged. However, the interactions between disinfectants and host local immunity are poorly understood. Objective – To assess the effects of chlorhexidine digluconate (Chx), with and without selected host defence ...
Domenico Santoro +3 more
wiley +1 more source
British Journal of Dermatology, 2019 特应性湿疹会导致皮肤瘙痒和失眠。它也与出现哮喘和过敏性鼻炎的风险增加相关。和这类过敏性疾病一样,特应性湿疹在西方社会很常见,但在贫穷和卫生环境较差的地区不常见。因此,在婴儿期缺乏免疫刺激(是指暴露于有助于免疫系统发育的某些虫类或“微生物”)可能是这类疾病的深层病因。金色葡萄球菌是一种寄生在皮肤上的细菌,而且通常在婴儿的肠道内定殖(生存并繁殖),在此它可以达到极高的数量。它会产生称作“超抗原”的毒素,其通常可导致“食物中毒”。但本次研究建议,让金色葡萄球菌在肠道内定殖实际上可能对幼儿有益 ...
F. Nowrouzian +5 more
semanticscholar +1 more source
特应性皮炎患者体内抗体盛行,对金黄色葡萄球菌抗原作出反应:系统性评述和元分析
British Journal of Dermatology, 2018 特应性皮炎(AD)是一种常见的湿疹。金黄色葡萄球菌(S.)是AD的致病因子之一,可以随各种细菌物质侵入人体。AD患者的身体免疫系统对这些物质作出反应时,可能会引起常见于AD的炎症反应。在本研究中,我们对现有文献(例如发布在医学期刊上的研究)进行了概述,总结了其中对照AD患者和健康对照组(非AD患者)得出的关于人体自身免疫系统对金黄色葡萄球菌物质(抗原)作出的免疫反应(抗体)的研究结论。科学文献从不同的数据库系统地获取。我们提取了有关多久可以在AD患者体内发现一次针对金黄色葡萄球菌的IgE型抗体(所谓的 ...
J. Wit +3 more
semanticscholar +1 more source