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Transdermal drug delivery in horses: An in vitro comparison of skin structure and permeation of two model drugs at various anatomical sites

open access: yesVeterinary Dermatology, Volume 34, Issue 3, Page 235-245, June 2023., 2023
Background – Oral and parenteral drug delivery in horses can be difficult. Equine‐specific transdermal drug formulations offer improved ease of treatment; development of such formulations requires a deeper understanding of the structural and chemical tissue barrier of horse skin. Hypothesis/Objectives – To compare the structural composition and barrier
Samuel C. Bizley   +3 more
wiley   +1 more source

Influence of Traditional Chinese Medicine emotion regulation on the psychological status and quality of life of patients undergoing hemodialysis for end-stage renal disease (中医情志护理干预对终末期肾病透析患者心理及生活质量的影响研究)

open access: yes中西医结合护理
Objective To investigate the influence of Traditional Chinese Medicine (TCM) emotion regulation on the psychological status and quality of life of patients undergoing hemodialysis for end-stage renal disease.
JIA Hengxia (贾恒霞)   +2 more
doaj   +1 more source

Research progress on Traditional Chinese Medicine nursing techniques for prevention and treatment of complications associated with hemodialysis in recent five years (近五年中医护理技术防治血液透析并发症的研究进展)

open access: yes中西医结合护理
With the increasing application of Traditional Chinese Medicine (TCM) nursing techniques in the field of hemodialysis, TCM nursing—leveraging its core strengths of a holistic approach and syndrome differentiation-based care—provides a significant ...
LIU Yulei (刘玉磊)   +3 more
doaj   +1 more source

External application of Xiaoding ointment in the treatment of swelling around arteriovenous fistula sites in patients with hemodialysis (消定膏对血液透析动静脉内瘘患者肿胀的临床疗效评价)

open access: yes中西医结合护理
Objective To observe the clinical effect of the external use of Xiaoding ointment in the treatment of swelling around arteriovenous fistula sites in patients with hemodialysis.
XU Xia (徐霞)   +5 more
doaj   +1 more source

Application of blood perfusion combined with hemodialysis and hemodiafiltration in preventing cardiac valvular calcification associated with maintenance hemodialysis

open access: yesLinchuang shenzangbing zazhi, 2020
目的分析血液灌流联合血液透析与血液透析滤过两种治疗方法在预防维持性血液透析心脏瓣膜钙化的中的应用效果。方法选取淮安市第一人民医院2017年1月至2018年1月期间收治的128例慢性肾衰竭血液透析患者,随机分为对照组与观察组各64例,观察组施以血液灌流联合血液透析治疗,对照组采用血液透析滤过治疗。分析两种治疗方法对维持性血液透析心脏瓣膜钙化的影响。结果两组治疗后钙化相关指标、生化指标监测结果以及不良反应发生情况对比,差异有统计学意义 ...
ZHUANG Ling   +3 more
doaj  

Clinical observations on anticoagulant efficacy of high-dose segmented citrate on high-flux hemodialysis

open access: yesLinchuang shenzangbing zazhi, 2021
目的观察高剂量枸橼酸进行分段体外抗凝高通量血液透析的抗凝效果及安全性。方法对2020年1月至2020年11月期间24例有高危出血风险的维持性血液透析患者行4%枸橼酸三钠抗凝治疗67例次,分别在透析器前后以200 mL/h的速度输入4%枸橼酸三钠,观察患者的临床不良反应、抗凝效果,比较透析前、透析2 h和透析后体内、体外血液pH值、钙离子、总钙、钠离子、碱剩余、碳酸氢根浓度的变化。结果 67例次的高剂量枸橼酸抗凝治疗各有1例分别因跨膜压、静脉压升高提前40 min和30 min结束治疗 ...
Ke Xiao-su, Li Yu-wei, Luo Li-xia
doaj  

One case of rhabdomyolysis resulting from fenofibrate in hemodialysis patients

open access: yesLinchuang shenzangbing zazhi, 2019
病例资料患者:女,59岁,2007年诊断为尿毒症并行血液透析治疗至今,目前透析方案为普通血液透析(hemodialysis,HD)4次/2周,血液透析滤过(hemodiafiltration,HDF)1次/2周,采用金宝AK96血液透析机,15 L/15 U合成膜透析器,透析液温度36.5 ℃,血流速250 mL/min,透析液流速500 mL/min,每次超滤量2~3 kg左右,无尿 ...
CHENG Li, XIONG Fei
doaj  

重组促红细胞生成素对血液透析患者铁代谢的影响

open access: yesZhongguo shiyan zhenduanxue, 2007
目的测定维持性血液透析患者血清促红细胞生成素(erythropoietin,EPO)及铁参数,探讨血液透析患者的铁代谢状况及重组EPO(recombinant human erythropoietin,rh-EPO)治疗对铁代谢的影响。方法选择单纯血液透析和接受rh-EPO治疗的血液透析患者31例,分别测定血常规及血清EPO、铁参数,并与健康对照组进行比较。结果血液透析患者和rh-EPO治疗的血液透析患者RBC、Hb、Hct、S、ITS显著低于健康对照组 ...
杜玉君, 王冠军, 窦海川, 艾清
doaj  

血液红细胞谷胱甘肽转移酶检测在维持血液透析者透析充分性评估中的临床意义研究

open access: yesZhongguo shiyan zhenduanxue, 2014
目的探讨维持血液透析患者红细胞谷胱甘肽S转移酶(GST)水平及其与透析充分性及炎症因子的相关性。方法根据单位室模型尿素指数值(spKt/V)将84例长期维持血液透析的终末期患者分为血液透析充分组(spKt/V≥1.3)33例以及血液透析不充分组(spKt ...
刘扬, 战海涛
doaj  

血清肝细胞生长因子水平与血液透析患者蛋白能量消耗的相关性研究

open access: yesZhongguo shiyan zhenduanxue, 2020
目的探讨血清肝细胞生长因子(hepatocyte growth factor,HGF)水平与血液透析患者蛋白能量消耗(protein energy wasting,PEW)的相关性。方法选取本院维持性血液透析治疗的128例终末期肾病(ESRD)患者,观察不同PEW患者临床基础资料及血清HGF水平差异,分析血HGF水平与患者年龄、透析时间、血白蛋白(albumin,Alb)、前白蛋白(proalbumin,PA)、血红蛋白(hemoglobin,Hb)、总胆固醇(total cholesterol,TC)、
史聪   +4 more
doaj  

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